Facial growth

面部生长
  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    目的:回顾支持颊脂肪垫(BFP)在原发性和继发性腭裂修复中的应用及其短期和长期临床结果的证据。
    方法:根据PRISMA指南,由2名独立审核员进行系统审查。
    文章是从三个数据库(Pubmed/Medline,Embase和WebofScience)。搜索词包括“腭裂”,\"腭成形术\",\"腭修复\",“颊脂肪垫”。
    方法:在原发性和继发性腭裂成形术中使用BFP。
    方法:主要结果是术后即刻并发症,术后瘘,和上颌生长。次要结果是腭长度,演讲,和供体部位发病率。
    结果:排除重复后,检索到91份报告。纳入23项研究(13项病例系列和10项比较研究)。总体证据水平较低。随机和非随机研究存在较高的偏倚风险。在原发性腭成形术中,BFP更常用于填充外侧松弛切口(57.4%),或在硬-软腭交界处和覆盖粘膜缺损(30.1%)。在这些患者中,术后瘘发生率为2.8%。两项研究发现,使用BFP后,上颌横尺寸更宽。没有较高的出血发生率,感染,开裂,或皮瓣坏死。在二次腭成形术中,在接受BFP治疗瘘管修复的患者中,未发现复发性瘘管.
    结论:BFP似乎与瘘管预防和管理的有利影响相关,以及上颌骨的横向生长。然而,研究之间存在高度异质性,偏倚风险高,总体证据质量低。有必要进行更多高质量的研究和长期随访。
    OBJECTIVE: To review the evidence supporting the use of buccal fat pad (BFP) in primary and secondary cleft palate repair and its short- and long- term clinical outcomes.
    METHODS: Systematic review conducted by 2 independent reviewers following PRISMA guidelines.
    UNASSIGNED: Articles were identified from three databases (Pubmed/Medline, Embase and Web of Science). Search terms included \"cleft palate\", \"palatoplasty\", \"palate repair\", \"buccal fat pad\".
    METHODS: Use of BFP in primary and secondary cleft palatoplasty.
    METHODS: Primary outcomes were immediate postoperative complications, postoperative fistula, and maxillary growth. Secondary outcomes were palatal length, speech, and donor site morbidity.
    RESULTS: Ninety-one reports were retrieved after excluding duplicates. Twenty-three studies were included (13 case series and 10 comparative studies). Overall level of evidence was low. Randomized and non-randomized studies had a high risk of bias. In primary palatoplasty, BFP was more frequently used filling lateral relaxing incisions(57.4%), or in the hard-soft palate junction and covering mucosal defects(30.1%). In these patients, post operative fistula incidence was 2.8%. Two studies found wider transverse maxillary dimensions after BFP use. No higher incidence of bleeding, infection, dehiscence, or flap necrosis was reported. In secondary palatoplasty, no recurrent fistulas were reported for patients undergoing BFP for fistula repair.
    CONCLUSIONS: BFP appears to be associated with a favorable impact in fistula prevention and management, as well as in transverse maxillary growth. However, there is a high heterogeneity among studies, high risk of bias and overall low quality of evidence. More high-quality research with long-term follow-up is warranted.
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  • 文章类型: Meta-Analysis
    The term « adenoid facies » suggests a causal relationship between nasopharyngeal obstruction and facial hyperdivergence in growing subjects. The strength of this association is controversial and few « quantified » values exist.
    A rapid electronic search was conducted on PubMed and Embase to find the main cephalometric studies involving patients with nasal/nasopharyngeal obstruction compared to a control sample. A meta-analysis was carried out to quantify the effect of obstruction (1) and intervention to relieve the obstruction (2) on mandibular divergence (SN/Pmand angle), maxillo-mandibular divergence (PP/Pmand angle), inclination of the occlusal plane (SN/Poccl) and the gonial angle (ArGoMe).
    Qualitatively, the studies\' bias level ranged from moderate to high. Results were concordant about the significant effect of the obstruction on facial divergence (1) with an increase in SN/Pmand (+3.6° on average, +4.1° in children <6 years), PP/Pmand (+5.4° on average, +7.7° <6 years), ArGoMe (+3.3°) and SN/Pocc (+1.9°). Surgical interventions to remove the respiratory obstacle in children (2) generally did not normalize the direction of growth, with the exception, with a very low level of evidence, of adenoidectomies/adeno-tonsillectomies, performed at an age less than 6-8 years.
    Early detection of respiratory obstacles and postural abnormalities associated with oral breathing appears to be decisive in order to hope for management at a young age and normalization of the direction of growth. However, the effects on mandibular divergence remain limited, requiring caution, and cannot be considered a surgical indication.
    Le terme « faciès adénoïdien » suggère une relation de causalité entre l’obstruction nasopharyngée et l’hyperdivergence chez le sujet en croissance. La force de cette association est controversée et peu de valeurs « chiffrées » existent.
    Une recherche électronique rapide a été menée sur PubMed et Embase pour retrouver les principales études céphalométriques impliquant des patients avec obstruction nasale/nasopharyngée comparés à une population témoin. Une métanalyse a été réalisée pour quantifier l’effet de l’obstruction (1) et de la désobstruction (2) sur la divergence mandibulaire (angle SN/Pmand), la divergence maxillo-mandibulaire (angle PP/Pmand), l’inclinaison du plan occlusal (SN/Poccl) et l’angle goniaque (ArGoMe).
    Qualitativement, le niveau de biais des études allait de modéré à élevé. Les résultats étaient concordants sur l’effet significatif de l’obstruction sur la divergence faciale (1) avec une augmentation de SN/Pmand (+3,6° en moyenne, +4,1° chez les enfants < 6 ans), PP/Pmand (+5,4° en moyenne, +7,7° < 6 ans), ArGoMe (+3,3°) et SN/Pocc (+1,9°). Les interventions chirurgicales pour lever l’obstacle respiratoire chez l’enfant (2) ne permettaient généralement pas une normalisation de la direction de croissance, à l’exception, avec un très faible niveau de preuve, des adénoïdectomies/adéno-amygdalectomies, réalisées à un âge inférieur à 6-8 ans.
    Le dépistage précoce des obstacles respiratoires et des anomalies posturales associées à la ventilation orale apparaît déterminant pour espérer une prise en charge en jeune âge et une normalisation de la direction de croissance. Les effets sur la divergence mandibulaire restent cependant limités, imposant la prudence et ne constituant pas une indication chirurgicale.
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  • 文章类型: Meta-Analysis
    目标:罗宾序列(RS),以微下颌畸形为特征,舌下垂,和上呼吸道阻塞,是一种越来越被认可的诊断。下颌骨牵张成骨(MDO)是一种有效的手术干预措施。这项研究分析了已发表的与MDO相关的面神经功能障碍(FND)的证据。
    方法:根据PRISMA指南,对2019年6月使用MESH术语查询的数据库进行了系统审查,或等效术语,如下:“牵张成骨”和“罗宾序列”。西班牙语和英语原文的评论,包括在内。结果指标包括FND的患病率;受影响的分支机构;永久性与永久性的比率瞬态FND;使用内部与外部设备;每日分心率;最后,总的分心长度。随后,我们进行了一项荟萃分析,对FND的患病率及其相关因素的结果进行了整理.
    结果:在确定的239项独特研究中,有729例患者的19项研究符合纳入标准;52例患者在MDO后发展为FND。随机效应荟萃分析得出FND的汇总患病率为6.40%,中等异质性研究(I2=41%,τ2=0.006)。下颌缘神经受累最常见。九项研究报告了暂时性FND,六个永久性的,一个都是,和两个未指定。在8项研究中使用了内部干扰物,在3项研究中使用了外部干扰物,在2项研究中均使用了外部干扰物。分心率为1.00至2.00毫米/天,总分心长度为13.00至22.3毫米。样本量是与FND速率成反比的唯一参数(p=0.04)。
    结论:对RS患者与MDO相关的FND分析显示缺乏一致的文献。MDO相关的FND似乎并不罕见,和永久性功能障碍可能发生。这篇评论强调了彻底的文档以阐明FND机制的重要性。
    Robin Sequence (RS), characterized by micrognathia, glossoptosis, and upper airway obstruction, is an increasingly recognized diagnosis. An effective surgical intervention is mandibular distraction osteogenesis (MDO). This study analyzes published evidence regarding facial nerve dysfunction (FND) associated with MDO.
    According to PRISMA guidelines, a systematic review was carried out with databases queried in June 2019 using MESH terms, or equivalent terms, as follows: \"distraction osteogenesis\" and \"Robin Sequence\". A review of original Spanish and English articles, were included. Outcome measures included the prevalence of FND; the affected branches; the rate of permanent vs. transient FND; the use of an internal vs. external device; the daily distraction rate; and finally, the overall distraction length. Subsequently, a meta-analysis was conducted to collate results regarding the prevalence of FND and the factors associated with it.
    Of 239 unique studies identified, 19 studies with 729 patients met inclusion criteria; 52 patients developed FND after MDO. A random-effects meta-analysis yielded a pooled prevalence of FND of 6.40%, with moderately heterogeneous studies (I2 = 41%, τ2 = 0.006). Marginal mandibular nerve involvement was most commonly noted. Nine studies reported transient FND, six permanent, one both, and two unspecified. Internal distractors were used in 8 studies and external in 3 and both in 2. Distraction rate was 1.00 to 2.00 mm/day and total distraction length ranged from 13.00 to 22.3 mm. Sample size was the only parameter inversely associated with rate of FND (p = 0.04).
    This analysis of FND associated with MDO for patients with RS demonstrates a lack of consistent documentation. MDO-associated FND does not appear to be uncommon, and permanent dysfunction can occur. This review underscores the importance of thorough documentation to elucidate the mechanism of FND.
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  • 文章类型: Journal Article
    The aim of the systematic review is to evaluate the effects of gingivoperiosteoplasty (GPP) on alveolar bone quality and facial growth in patients with cleft lip and palate (CLP).
    Electronic and manual search was done up to October 2017.
    Clinical and observational studies that compared GPP to control; patients without GPP evaluated either before or after the age for secondary bone graft (SBG).
    Studies selection was done by 2 authors independently. Risk ratio and mean difference with 95% confidence intervals (CIs) were calculated using random-effects models.
    Thirteen articles were included in the review. All studies were at high risk of bias. Poorer alveolar bone quality was found in the GPP group compared to the SBG group. The pooled data showed a statistically significant increase in the incidence of Bergland type III in the GPP group compared to SBG (risk ratio: 11.51, 95% CI: 3.39-35.15). As for facial growth, GPP group resulted in a more retruded maxillary position (as indicated by \"Sella-Nasion-Subspinale\" angle [SNA value]) compared to control group by -1.36 (CI: -4.21 to 1.49) and -1.66 (CI: -2.48 to -0.84) when evaluated at 5 and 10 years, respectively. The protocol for presurgical infant orthopedics used in conjunction with the GPP procedure might have affected the results of the alveolar bone and facial growth outcomes.
    Definitive conclusions about the effectiveness of GPP cannot be drawn. Very weak evidence indicated that GPP might not be an efficient method for alveolar bone reconstruction for patients with unilateral and bilateral CLP. Gingivoperiosteoplasty surgery could lead to maxillary growth inhibition in patients with CLP.
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  • 文章类型: Journal Article
    It is widely accepted that all dentists should have a thorough understanding of the muscles involved in moving or stabilizing the mandible. However, there is still much discussion regarding the influence of the mandibular muscles on normal facial growth and dental development, as well as on orthodontic treatment and post-treatment stability. Potential patients with different underlying vertical muscle patterns will have differences in the expected directions of future mandibular growth, lateral profile shape, facial and arch widths and vertical occlusal relationships. In turn, thorough diagnoses are likely to lead to differences in individual aims and objectives, treatment plans, timing of commencement, mechanical design, lateral profile and smile-aesthetics outcomes, choice of retention and plans for long-term maintenance. The potential influence of the mandibular muscles on normal morphologic variation and the soft tissue implications on contemporary orthodontic treatment and stability will be addressed in this review.
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  • 文章类型: Journal Article
    There is a lack of high-level evidence on the surgical management of cleft palate. An appreciation of the differences in the complication rates between different surgical techniques and timing of repair is essential in optimizing cleft palate management.
    A comprehensive electronic database search will be conducted on the complication rates associated with cleft palate repair using MEDLINE, EMBASE, and the Cochrane Central Register of Controlled Trials. Two independent reviewers with expertise in cleft pathology will screen all appropriate titles, abstracts, and full-text publications prior to deciding whether each meet the predetermined inclusion criteria. The study findings will be tabulated and summarized. The primary outcomes will be the rate of palatal fistula, the incidence and severity of velopharyngeal insufficiency, and the rate of maxillary hypoplasia with different techniques and also the timing of the repair. A meta-analysis will be conducted using a random effects model.
    The evidence behind the optimal surgical approach to cleft palate repair is minimal, with no gold standard technique identified to date for a certain type of cleft palate. It is essential to appreciate how the complication rates differ between each surgical technique and each time point of repair, in order to optimize the management of these patients. A more critical evaluation of the outcomes of different cleft palate repair methods may also provide insight into more effective surgical approaches for different types of cleft palates.
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  • 文章类型: Journal Article
    The vomer flap technique for repair of the hard palate is assumed to improve maxillary growth because it causes less scarring in growth-sensitive areas of the palate. The aim of this systematic review was to investigate the effect of techniques using the vomer flap compared with the palatal flap on facial growth in patients with cleft lip and palate. All papers published before 21 July 2012 were sought in the databases PubMed and MEDLINE. Search terms included \"facial growth\", \"cleft lip and palate\", \"palatal repair technique\", and \"vomer flap\". Additional studies were identified by hand searching the reference lists of the papers retrieved from the electronic search. Two independent reviewers assessed the eligibility of studies for inclusion, extracted the data, and assessed the quality of the methods. Six studies met the selection criteria. Outcomes assessed in 4 studies were dentofacial morphology after vomer or palatal flap, maxillary dental arch in 1 study, and dental arch relations in 2 studies. The quality of the methods used in 3 studies was poor. Contradictory results and a lack of high-quality and long-term outcomes of reviewed studies provided no conclusive scientific evidence about whether the vomer flap technique has more or less of an adverse effect on maxillary growth than the palatal flap. Further well-designed, well-controlled, and long-term studies particularly of the vomer flap (2-stage) and palatal flap (von Langenbeck or two-flap, 1-stage) are needed.
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