Excision

切除术
  • 文章类型: Journal Article
    导言虽然有效,传统的痔疮切除术(CEH)可能与显著的术后疼痛相关.建议采用新技术,例如经肛门痔疮去动脉化(THD),以减轻疼痛。但可能导致更高的复发率。我们的目的是在本荟萃分析中比较CEH和THD的短期和长期结果。方法进行符合PRISMA的荟萃分析,搜索PubMed,从1995年到2022年12月,用于随机对照试验(RCT)的EMBASE和CENTRAL数据库。主要目标是复发。次要目标包括并发症发生率,停留时间(LOS)手术时间和返回基线的时间。随机效应模型用于计算合并效应大小估计值。还进行了亚组分析。结果共捕获6个RCT,包括465例患者。CEH组中有142名(59%)男性,THD组中有129名(54%)男性。.关于随机效应分析,THD具有较高的复发率(OR=2.76,95%CI=1.03至7.38,p=0.04),尽管与CEH相比基线恢复较短(MD=-14.05天,95%CI=-20.38至-7.72,p<0.0001)。出血没有差异(p=0.12),尿潴留(p=0.97),失禁(p=0.41),肛门狭窄(p=0.19),血栓性残余痔疮(p=0.16),操作时间(p=0.19)或LOS(p=0.22)。亚组分析结果相似。结论CEH与THD的复发率较低,并发症发生率无差异。尽管患者术后恢复基线功能需要更长的时间。
    BACKGROUND: Although effective, conventional excisional haemorrhoidectomy (CEH) is associated with significant postoperative pain. Novel techniques such as transanal haemorrhoidal dearterialization (THD) are suggested to reduce pain but may result in higher recurrence rates. We aimed to compare short- and long-term outcomes of CEH and THD in the present meta-analysis.
    METHODS: A PRISMA-compliant meta-analysis was performed, searching PubMed, Embase, and CENTRAL databases for randomised controlled trials (RCTs) from 1995 to December 2022. The primary objective was recurrence. Secondary objectives included complication rates, length of stay (LOS), operative time, and time to return to baseline. Random-effects models were used to calculate pooled effect size estimates. Subgroup analysis was also performed.
    RESULTS: A total of 6 RCTs encompassing 465 patients were captured. There were 142 (59%) males in the CEH group and 129 (54%) in the THD group. On random-effects analysis, THD had a higher recurrence rate (odds ratio = 2.76, 95% confidence interval [CI] = 1.03-7.38, p = 0.04) albeit a shorter return to baseline compared to CEH (mean difference = -14.05 days, 95% CI = -20.38 to -7.72, p < 0.0001). There were no differences in bleeding (p = 0.12), urinary retention (p = 0.97), incontinence (p = 0.41), anal stenosis (p = 0.19), thrombosed residual haemorrhoids (p = 0.16), operating time (p = 0.19), or LOS (p = 0.22). Results remained similar on subgroup analysis.
    CONCLUSIONS: CEH is associated with lower recurrence but similar complication rates to THD, although patients take longer to return to baseline function postoperatively.
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  • 文章类型: Journal Article
    背景:目前的文献缺乏比较足底和背侧方法治疗Civinini-Morton综合征的临床结果的全面信息,也被称为莫顿神经瘤。进行了系统评价和荟萃分析,以评估和比较Morton神经瘤的神经切除术的临床结果。重点研究足底入路和背侧入路的差异。
    方法:我们的综合文献综述遵循了系统评价和荟萃分析(PRISMA)指南的首选报告项目,并利用了包括PubMed,Embase,WebofScience,还有Cochrane图书馆.这项研究中调查的数据包括术后感觉丧失,疤痕压痛,再操作,组织病理学,并发症,疼痛评分,患者满意度,功能分数,和负重时间。
    结果:本研究共纳入8项研究。总的来说,使用足底入路切除237例神经瘤,而312个神经瘤通过背侧入路治疗。在背侧组中发现术后感觉降低的比率明显更高:48.5%(64/132)Vs。62.0%(80/129),相对比率(RR)为0.79(95%CI,0.64-0.97)。足底组术后瘢痕压痛的发生率明显更高:16.7%(32/192)Vs。6.2%(14/225),RR为2.27(95%CI,1.28-4.04)。关于组织病理学,足底入路和背侧入路的准确率分别为99.3%(143/144)和97.1%(134/138),分别,RR为1.02(95%CI,0.98-1.07)。两组之间的总体再手术和并发症没有差异,足底组为5.3%(10/189)和8.8%(19/216),背侧组为6.1%和12.0%(35/291)。
    结论:我们建议在手术前与患者进行详细讨论,以权衡每种方法的优缺点。
    BACKGROUND: Current literature lacks comprehensive information comparing the clinical outcomes of plantar and dorsal approaches for Civinini-Morton syndrome, also known as Morton\'s neuroma. This systematic review and meta-analysis was conducted to evaluate and compare the clinical outcomes of neurectomy for Morton\'s neuroma, focusing on the differences between the plantar and dorsal approach.
    METHODS: Our comprehensive literature review adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and utilized databases including PubMed, Embase, Web of Science, and the Cochrane Library. Data investigated in this study included postoperative sensory loss, scar tenderness, reoperation, histopathology, complications, pain score, patient satisfaction, functional scores, and time to weight bearing.
    RESULTS: Total eight studies were included in this study. In aggregate, 237 neuromas underwent excision using the plantar approach, while 312 neuromas were treated via the dorsal approach. A significantly higher rate of postoperative reduced sensory was found in the dorsal group: 48.5 % (64/132) Vs. 62.0 % (80/129) with the relative ratio (RR) of 0.79 (95 % CI, 0.64-0.97). A significantly higher rate of postoperative scar tenderness was noted in the plantar group: 16.7 % (32/192) Vs. 6.2 % (14/225) with the RR of 2.27 (95 % CI, 1.28-4.04). Regarding the histopathology, 99.3 % (143/144) and 97.1 % (134/138) accuracy rate was confirmed in the plantar approach and dorsal approach, respectively, with the RR of 1.02 (95 % CI, 0.98-1.07). Overall reoperations and complications were not different between groups at 5.3 % (10/189) and 8.8 % (19/216) in the plantar group versus 6.1 % and 12.0 % (35/291) in dorsal group.
    CONCLUSIONS: We recommend detailed discussions with patients prior to surgery to weigh the advantages and disadvantages of each approach.
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  • 文章类型: Case Reports
    背景:支气管源性囊肿是一种罕见的发育异常,属于先天性肠源性囊肿。它们来自肺芽,并在出生时存在。胚胎前肠是它们的起源。通常,它们位于胸腔内,特别是在胸腔的腔内纵隔或滞留在肺实质中,被认为是一种肺芽畸形。
    方法:一名49岁男性患者因体格检查中发现腹膜后肿块而入院。入院前两周,患者接受了体格检查和常规实验室检查,显示腹膜后区域有一个占位性肿块。患者未报告任何症状(如腹痛,胀气,恶心,呕吐,高烧,或发冷)。计算机断层扫描(CT)显示腹膜后占位性病变,增强最小,CT值为约36Hounsfield单位。病变未从胰体边界划定,与腹膜后局部密切相关。
    结论:经过一系列测试,确认了一个腹部肿块,提示实施腹腔镜腹膜后肿块切除术。在调查过程中,在胰腺的上后部区域发现了一个8cm×7cm的囊性圆形肿块,有明显的分界。随后,对肿块进行了完全切除.术后病理检查发现囊性肿块,其特征是内壁光滑。发现囊性肿块含有白色,其胶囊内的粘性液体。
    BACKGROUND: Bronchogenic cysts are rare developmental anomalies that belong to the category of congenital enterogenous cysts. They arise from lung buds and are present at birth. The embryonic foregut is their origin. Typically, they are located within the chest cavity, particularly in the cavum mediastinale of the thoracic cavity or lodged in the pulmonary parenchyma, and are considered a type of lung bud malformation.
    METHODS: A 49-year-old male patient was admitted to the hospital due to the detection of a retroperitoneal mass during a physical examination. Two weeks before admission, the patient underwent a physical examination and routine laboratory tests, which revealed a space-occupying mass in the retroperitoneal region. The patient did not report any symptoms (such as abdominal pain, flatulence, nausea, vomiting, high fever, or chills). The computed tomography (CT) revealed a retroperitoneal space-occupying lesion with minimal enhancement and a CT value of approximately 36 Hounsfield units. The lesion was not delineated from the boundary of the pancreatic body and was closely related to the retroperitoneum locally.
    CONCLUSIONS: Following a series of tests, an abdominal mass was identified, prompting the implementation of a laparoscopic retroperitoneal mass excision procedure. During the investigation, an 8 cm × 7 cm cystic round-shaped mass with a distinct demarcation was identified in the upper posterior region of the pancreas. Subsequently, full resection of the mass was performed. Postoperative pathological examination reveled a cystic mass characterized by a smooth inner wall. The cystic mass was found to contain a white, viscous liquid within its capsule.
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  • 文章类型: Journal Article
    用于治疗黑色素瘤的Mohs显微手术(MMS)比广泛的局部切除术(WLE)具有多种优势,包括完整的组织学边缘评估,当天切除和闭合,并在关键解剖部位保留健康组织。最近,大量的临床数据证明了MMS治疗黑色素瘤的有效性,导致新出现的患者安全考虑发生的治疗费用,肿瘤分期的风险,前哨淋巴结活检(SLNB)的护理协调失败。彩信提供保险箱,有效,以及基于价值的原位黑色素瘤(MIS)和侵袭性黑色素瘤(IM)治疗,特别是在冷冻切片上使用免疫组织化学。与WLE相比,MMS治疗显示类似或改善局部肿瘤复发的结果,黑色素瘤特异性生存率,和长期随访的总生存率。肿瘤分期风险低,如果存在,对临床管理的改变是最小的。对于符合条件的头颈部IM病例,应在MMS之前进行SLNB的讨论。虽然具有挑战性,已经证明了SLNB与MMS的成功多学科协调。在这里,我们对MMS治疗皮肤黑色素瘤的证据进行了详细的临床回顾,并就解决目前围绕MIS和IM外科治疗模式不断发展的争议提出了建议.
    Mohs Micrographic Surgery (MMS) for treatment of melanoma offers several advantages over wide local excision (WLE), including complete histologic margin evaluation, same-day resection and closure, and sparing of healthy tissue in critical anatomic sites. Recently, a large volume of clinical data demonstrating efficacy in MMS treatment of melanoma was published, leading to emerging patient safety considerations of incurred treatment costs, risk of tumor upstaging, and failure of care coordination for sentinel lymph node biopsy (SLNB). MMS offers a safe, effective, and value-based treatment for both melanoma in situ (MIS) and invasive melanoma (IM), particularly with immunohistochemistry use on frozen sections. Compared to wide local excision, MMS treatment demonstrates similar or improved outcomes for local tumor recurrence, melanoma-specific survival, and overall survival at long-term follow-up. Tumor upstaging risk is low, and if present, alteration to clinical management is minimal. Discussion of SLNB for eligible head and neck IM cases should be done prior to MMS. Though challenging, successful multidisciplinary coordination of SLNB with MMS has been demonstrated. Herein, we provide a detailed clinical review of evidence for MMS treatment of cutaneous melanoma and offer recommendations to address current controversies surrounding the evolving paradigm of surgical management for both MIS and invasive melanoma (IM).
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  • 文章类型: Case Reports
    背景:Bowen病(BD)代表一种原位鳞状细胞癌,无需治疗即可发展为浸润性鳞状细胞癌。已经描述了鲍恩病的各种选择,每一个都有它的优点和缺点。
    方法:我们报告了一例60岁患者,有慢性吸烟史,有多个伴侣和复发性尿道炎的背景。患者表现为阴茎外侧有斑丘疹性病变,进化了5年。活检证实了Bowen病的诊断。该患者接受了病变切除,组织学显示为浸润性基底鳞状细胞癌。
    结论:Bowen病的诊断需要活检和组织学检查。只有手术治疗才能进行鉴定,通过对切除标本的组织学分析,活检中可能未发现的任何潜在侵入性区域。非手术疗法也是一种高复发率的选择。
    结论:Bowen的疾病管理需要个性化的方法,考虑到病变特征等因素,患者相关变量和治疗效果。由于与各种治疗相关的复发风险,建议进行适应性随访。
    BACKGROUND: Bowen\'s disease (BD) represents an in situ squamous cell carcinoma that can progress to an invasive one without treatment. Various options for Bowen\'s disease have been delineated, each with its set of advantages and disadvantages.
    METHODS: We report the case of a 60-year-old patient with a history of chronic smoking and a background of multiple partners and recurrent urethritis. The patient presented with a maculopapular lesion on the lateral aspect of the penis, evolving for 5 years. A biopsy confirmed the diagnosis of Bowen\'s disease. The patient underwent an excision of the lesion which the histology showed an infiltrating basosquamous cell carcinoma.
    CONCLUSIONS: The diagnosis of Bowen\'s disease requires a biopsy and is based on histological examination. Only surgical treatment allows for the identification, through histological analysis of the excised specimen, of any potential invasive area that may not have been identified in the biopsy. Nonsurgical therapies are also an option with high recurrence rates.
    CONCLUSIONS: Bowen\'s disease management requires a personalized approach, considering factors like lesion characteristics, patient-related variables and treatment efficacy. An adapted follow-up is recommended due to the recurrence risk associated with various treatments.
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  • 文章类型: Journal Article
    虽然大多数摩擦烧伤在门诊得到了充分的管理,许多人可能需要住院,手术切除,和扩展护理。直到今天,摩擦烧伤管理存在很大差异。我们的目标是回顾病因,管理,以及此类烧伤的结果需要住院治疗。我们对所有承认的摩擦烧伤进行了回顾性审查,2016年1月1日至2020年12月31日,由美国烧伤协会验证的烧伤中心。共有28名(34%)患者因摩擦烧伤而需要手术,最终有15名(18%)患者需要进行分层厚度的皮肤移植。平均手术次数为2.4(95%CI1.6-3.1)。总的来说,手术组年轻(29.9岁vs38.3岁,P=.026),更有可能伴随创伤性脑损伤(25%对7%,P=.027),住院时间更长(17.5天vs3.9天,P<.001)。两组总体TBSA相似(8.5%vs10.0%,P=.35),但是手术组的表面积更大,包括三度烧伤(3.05%vs0.2%,P<.001)。总的来说,导致入院的摩擦烧伤与高能量创伤机制和伴随损伤有关。需要对烧伤进行手术干预的患者通常需要进行多次手术,通常最终进行厚度分裂的皮肤移植。虽然使用局部药物对摩擦烧伤的非手术治疗已被发现是成功的,损伤严重程度评分较高的患者应密切监测,因为他们可能需要手术切除.
    While most friction burns are adequately managed in an outpatient setting, many may require hospital admission, operative excision, and extended care. To this day, there is a wide variance in friction burn management. Our goal is to review the etiology, management, and outcomes of such burns warranting hospitalization. We conducted a retrospective review of all friction burns admitted to a single, American Burn Association-verified burn center from January 1, 2016 to December 31, 2020. A total of 28 (34%) patients required surgery for their friction burns and 15 (18%) ultimately required a split-thickness skin graft. The mean number of operations was 2.4 (95% CI 1.6-3.1). Overall, the operative group was younger (29.9 vs 38.3 years, P = .026), more likely to have a concomitant traumatic brain injury (25% vs 7%, P = .027), and had a longer hospital length of stay (17.5 vs 3.9 days, P < .001). Both groups had a similar overall TBSA (8.5% vs 10.0%, P = .35), but the operative group had a larger surface area comprised of third-degree burns (3.05% vs 0.2%, P < .001). Overall, friction burns resulting in hospital admission are associated with high-energy traumatic mechanisms and concomitant injuries. Patients who need operative intervention for their burns typically require multiple procedures often culminating in a split-thickness skin graft. While non-operative management of friction burns with topical agents has been found to be successful, patients with higher injury severity scores should be monitored very closely as they may require surgical excision.
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  • 文章类型: Case Reports
    脂肪瘤是由间充质前脂肪细胞引起的生长缓慢的良性软组织肿瘤。组织学上它们由成熟的脂肪细胞组成。它们通常在体内有类似披肩的分布,从皮下空间到骨头的任何地方,但很少出现在手中。当>5厘米时,它们被称为“巨大脂肪瘤”,由于神经血管压迫和手功能受损,可能有症状。
    方法:一位51岁的法医分析师在他的惯用右手的大鱼间隆起和手掌上出现了一个逐渐扩大的肿块,持续了2年。虽然最初无症状,他在radial骨21/2手指上逐渐麻木,并且由于其大小导致职业性损害而导致手功能受损。检查发现手掌上有一个5x5cm无痛的小叶肿块。NCS显示正中神经受压的证据。MR成像显示一个巨大的脂肪瘤,涉及鱼际和中掌空间。进行了整块手术切除,组织学证实。
    手部脂肪瘤可能是浅表或深空。它们生长缓慢,最初无症状,由于美容问题而引起注意,神经压迫或机械手损伤伴扩大。由于脂肪肉瘤和肉瘤改变的风险,必须怀疑巨大脂肪瘤。
    结论:手部巨大的多室脂肪瘤是罕见的。提倡手术切除怀疑是恶性肿瘤,神经压迫和功能限制。无碎裂的整块切除术具有最小的复发和并发症风险。
    UNASSIGNED: Lipomas are slow growing benign soft tissue tumors that arise from mesenchymal preadipocytes. Histologically they are composed of mature adipocytes. They typically have a shawl like distribution in the body, anywhere from the subcutaneous space to bone, but are seen only rarely in the hand. When >5 cm, they are referred to as \'giant lipoma\' and can be symptomatic due to neurovascular compression and impaired hand function.
    METHODS: A 51-year-old forensic analyst presented with a progressively enlarging lump over the thenar eminence and palm of his dominant right hand for 2 years duration. Although initially asymptomatic, he developed progressive numbness over the radial 21/2 fingers and impaired hand function due to its size resulting in occupational impairment. Examination revealed a 5x5cm painless lobulated lump over palm. NCS showed evidence of median nerve compression. MR imaging revealed a giant lipoma involving the thenar and midpalmar space. Enbloc surgical excision was performed and histology was confirmatory.
    UNASSIGNED: Lipomas of the hand could be superficial or deep space. They are slow growing and asymptomatic initially and are brought to attention due to cosmetic concerns, nerve compression or mechanical hand impairment with enlargement. Giant lipomas must be treated with suspicion due to denovo liposarcoma and risk of sarcomatous change.
    CONCLUSIONS: Giant multi-compartment lipomas of the hand are rare. Surgical excision is advocated for suspicion of malignancy, nerve compression and functional limitation. Enbloc resection without fragmentation has minimal risk of recurrence and complications.
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  • 文章类型: Journal Article
    手术广泛局部切除术(WLE)仍然是原发性皮肤黑色素瘤的当前护理标准。WLE是一种选择性程序,旨在实现局部疾病控制,同时减少功能和美容损害。尽管有几项前瞻性随机试验,切除边缘的最佳范围仍然存在争议,这反映在全球准则持续缺乏共识。此外,现在,在手术在黑色素瘤治疗中不断演变的作用的背景下,解释现有的试验数据存在额外的困难,随着我们对临床病理和基因组预后标志物的了解增加,导致经常常规使用前哨淋巴结活检(SNB)作为分期程序,除了针对高危疾病的辅助系统疗法的开发。正在进行的审判,MelMarT-II,设计的目的是获得一个明确的答案来指导这一基本的手术决定。
    Surgical wide local excision (WLE) remains the current standard of care for primary cutaneous melanoma. WLE is an elective procedure that aims to achieve locoregional disease control with minimal functional and cosmetic impairment. Despite several prospective randomised trials, the optimal extent of excision margin remains controversial, and this is reflected in the persistent lack of consensus in guidelines globally. Furthermore, there is now the added difficulty of interpreting existing trial data in the context of the evolving role of surgery in the management of melanoma, with our increased understanding of clinicopathologic and genomic prognostic markers leading to the often routine use of sentinel node biopsy (SNB) as a staging procedure, in addition to the development of adjuvant systemic therapies for high-risk disease. An ongoing trial, MelMarT-II, has been designed with the aim of achieving a definitive answer to guide this fundamental surgical decision.
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  • 文章类型: Journal Article
    血管脂肪瘤是一种良性间叶性肿瘤,在头颈部发生非常罕见。医学文献中仅报道了2例喉血管脂肪瘤。我们在一名32岁的男性中出现了一例罕见病例,该男性自过去9个月以来一直抱怨喉咙的声音和异物感发生变化,并伴有阻塞性睡眠呼吸暂停和吞咽困难的特征。颈部对比增强CT扫描显示,右心室向上延伸直至瓣膜,引起囊性病变,部分阻塞气道。怀疑是声门上囊肿,计划经口显微喉镜KTP-532激光辅助切除,术中遇到实体瘤。我们在此讨论这种罕见肿瘤的临床表现和治疗,并回顾文献。
    Angiolipoma is a benign mesenchymal tumor and its occurrence in head and neck region is very rare. Only 2 cases of Laryngeal angiolipomas have been reported in the medical literature. We present one such rare case in a 32-year-old male who presented with complaints of change in voice and foreign body sensation in the throat since past 9 months along with features suggestive of obstructive sleep apnoea and dysphagia. Contrast enhanced CT scan of the neck showed a cystic lesion arising from right ventricle extending superiorly till the vallecula, partially obstructing the airway. Suspecting a supraglottic cyst, trans-oral microlaryngoscopic KTP-532 laser assisted excision was planned, intraoperatively a solid tumor was encountered. We discuss herein the clinical presentation and management of this rare neoplasm with review of literature.
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  • 文章类型: Case Reports
    胫骨远端的骨间部分是骨软骨瘤可能发生的区域之一。骨软骨瘤通常发生在成长中的儿童中,并通过其对腓骨的压力作用引起逐渐的踝关节畸形。我们介绍了6例胫骨远端骨间骨软骨瘤患者(5名男孩和1名女孩,中位年龄为13岁)。他们在病变的近端和远端通过围绕其纵轴的180腓骨截骨术进行治疗。所有患者均接受治疗,除一例发生腓骨截骨部位骨不连外,均无任何并发症。在最后的后续行动中,所有的病人都没有痛苦,无复发报告。已经描述了用于切除胫骨远端骨间骨软骨瘤的各种方法。有或没有腓骨截骨术,切除手术期间有或没有踝关节畸形的急性矫正。尽管如此,对于切除此类病变的最佳方法尚无共识。
    The interosseous part of the distal tibia is one of the regions in which osteochondroma can occur. Osteochondroma typically occurs among growing children and causes gradual ankle deformity by its pressure effect on the fibula. We presented six patients (Five boys and one girl with median age of 13 years old) with distal tibial interosseous osteochondroma. They were treated by a 180̊ fibular osteotomy around its longitudinal axis just proximal and distal to the lesion. All patients were treated without any complication except for one who developed non-union of the site of the fibular osteotomy. In the last follow-up, all the patients were pain-free, and no recurrence was reported. Various methods have been described for resecting interosseous osteochondroma of the distal tibia, with or without fibular osteotomy and with or without acute correction of ankle deformity during resection surgery. Still, there is no consensus over the best method for resecting such lesions.
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