背景:费氏大肠杆菌是人类和动物中一种罕见的机会性病原体,尤其是生物膜。
方法:在一种情况下,在胆汁中检测到具有生物膜的E.Fergusonii,并用银染证明它有生物膜。并对文献检索到的8例E.ergusonii的临床特点及药敏情况进行了总结。
结果:这是一例带有生物膜的E.Fergusonii,这在中国还没有报道。从文献中检索到的8例没有说明它们是否有生物膜,但我们分析了他们的临床特点和药物敏感性。所有患者均接受抗菌药物治疗。8例患者对哌拉西林/他唑巴坦和亚胺培南敏感6例(75%),但对左氧氟沙星和环丙沙星敏感性差。
结论:在这种情况下,银染法证明了生物膜,这是中国首例带有生物膜的E.Fergusonii。
BACKGROUND: Escherichia fergusonii is a rare opportunistic pathogen in humans and animals, especially with biofilm.
METHODS: In one case, E. fergusonii with biofilm was detected in the bile, and silver staining was used to prove it had biofilm. The clinical characteristics and drug susceptibility of eight cases of E. fergusonii retrieved from the literature were also summarized.
RESULTS: This is a case of E. fergusonii with biofilm, which has not been reported in China. The 8 cases retrieved from the literature did not specify whether they had biofilm, but we analyzed their clinical characteristics and drug susceptibility. All patients were treated with antimicrobial drugs. 8 cases showed sensitivity to piperacillin/tazobactam and imipenem in 6 cases (75%), but poor sensitivity to levofloxacin and ciprofloxacin.
CONCLUSIONS: The silver staining method proved biofilm in this case, which is the first case of E. fergusonii with biofilm in China.