EAACI关于短期暴露于室外污染物对哮喘相关结果的影响的指南为预防提供了建议。患者护理和缓解是一个框架,支持医疗保健专业人员和患者的合理决策,以个性化和改善哮喘管理,并为决策者和监管机构提供循证参考,以帮助在国际上制定具有法律约束力的室外空气质量标准和目标。国家和地方层面。该指南是使用GRADE方法制定的,并评估了世界卫生组织当前空气质量指南中引用的室外污染物,即单一或混合污染物和室外农药。短期暴露于所有评估的污染物会增加哮喘相关不良结局的风险,尤其是住院和急诊科就诊(在特定的滞后日有适度的证据确定性)。与交通有关的空气污染和室外农药暴露的影响以及减少排放的干预措施的证据有限。由于证据的质量,为所有污染物和减少室外空气污染的干预措施制定了有条件的建议。目前的EAACI指南建议的哮喘管理可以改善哮喘相关的结果,但需要采取全球清洁空气措施才能取得显著影响。
The EAACI
Guidelines on the impact of short-term exposure to outdoor pollutants on asthma-related outcomes provide recommendations for prevention, patient care and mitigation in a framework supporting rational decisions for healthcare professionals and patients to individualize and improve asthma management and for policymakers and regulators as an evidence-informed reference to help setting legally binding standards and goals for outdoor air quality at international, national and local levels. The
Guideline was developed using the GRADE approach and evaluated outdoor pollutants referenced in the current Air Quality
Guideline of the World Health Organization as single or mixed pollutants and outdoor pesticides. Short-term exposure to all pollutants evaluated increases the risk of asthma-related adverse outcomes, especially hospital admissions and emergency department visits (moderate certainty of evidence at specific lag days). There is limited evidence for the impact of traffic-related air pollution and outdoor pesticides exposure as well as for the interventions to reduce emissions. Due to the quality of evidence, conditional recommendations were formulated for all pollutants and for the interventions reducing outdoor air pollution. Asthma management counselled by the current EAACI
guidelines can improve asthma-related outcomes but global measures for clean air are needed to achieve significant impact.