Endovascular embolization

血管内栓塞
  • 文章类型: Case Reports
    在通过传统的经皮方法无法进入所涉及的静脉窦段的情况下,高级硬脑膜动静脉瘘(dAVF)的最佳血管内管理在技术上具有挑战性。在这份报告中,我们描述了经颅血管内入路治疗高级别dAVF的经验.我们还提供了经颅血管内dAVF栓塞的其他报道的文献综述。我们建议,在仅经皮途径无法进入瘘管的情况下,高等级dAVF的经颅血管内栓塞似乎是安全有效的。
    The optimal endovascular management of high-grade dural arterial-venous fistulae (dAVF) can be technically challenging in cases where the involved venous sinus segment is inaccessible through the traditional percutaneous approach. In this report, we describe our experience with the transcranial endovascular approach for the treatment of a high-grade dAVF. We also provide a literature review of other reports of transcranial endovascular dAVF embolization. We propose that transcranial endovascular embolization of high-grade dAVF appears to be safe and effective in cases where the fistula is inaccessible to percutaneous routes alone.
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  • 文章类型: Systematic Review
    目的:评估术前血管内栓塞(EE)和手术切除(SE)联合方法治疗头皮动静脉畸形(AVM)的疗效,并提供说明性病例报告。
    方法:使用在线数据库进行了系统评价(PubMed/Medline,科克伦,和Embase)于2023年2月15日。纳入标准是对头皮AVM患者进行的任何类型的研究,这些患者通过血管造影进行诊断和确认,并接受术前EE和SE的联合治疗。所有符合纳入标准的文章均纳入本研究。
    结果:共纳入49篇文献(91例患者)。患者在就诊时的年龄范围为10天至70岁。最常见的症状是搏动性肿块51例(56.04%),31例患者的肿块逐渐增加(34.06%),22例患者出现瘀伤和/或惊厥(24.17%)。术前EE和SE并发症仅在5例患者中观察到;3例患者(3.29%)收获了植皮边缘坏死,1例(1.09%)皮肤坏死,1例(1.09%)伤口感染。在12个月的中位随访期内,只有两名患者(2.19%)报告了复发或残留的肿块。
    结论:头皮AVM的管理可能具有挑战性;因此,专注,并且需要准确识别血管解剖结构的复杂性。术前EE和SE联合治疗的结果令人满意,并发症和复发率低;因此,我们推荐这种方法用于头皮AVM的管理。
    To evaluate the efficacy of the combined approach of preoperative endovascular embolization (EE) and surgical excision (SE) for scalp arteriovenous malformation (AVM) and present an illustrative case report.
    A systematic review was conducted using online databases (PubMed/Medline, Cochrane, and Embase) on February 15, 2023. The inclusion criteria were any type of study of patients with scalp AVMs who were diagnosed and confirmed through angiography and treated with combined preoperative EE and SE. All the articles that met the inclusion criteria were included in this study.
    A total of 49 articles (91 patients) were included. The patients\' age ranged from 10 days to 70 years at the time of presentation. The most common symptoms were a pulsatile mass in 51 patients (56.04%), progressively growing mass in 31 patients (34.06%), and bruits and/or thrills in 22 patients (24.17%). Complications of preoperative EE and SE were observed in only 5 patients; 3 patients (3.29%) had harvested skin graft marginal necrosis, 1 patient (1.09%) had skin necrosis, and 1 patient (1.09%) had a wound infection. Only 2 patients (2.19%) reported a recurrent or residual mass during a median follow-up period of 12 months.
    The management of scalp AVMs can be challenging; therefore, focused, and accurate identification of the complexity of the vascular anatomy is required. The combined method of preoperative EE and SE showed satisfactory outcomes with low rates of complications and recurrence; thus, we recommend this approach for the management of scalp AVMs.
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  • 文章类型: Systematic Review
    脑脊液(CSF)-静脉瘘可引起自发性颅内低血压(SIH),并提出了重大的诊断和管理挑战。本研究旨在全面概述血管内栓塞作为SIH患者CSF-静脉瘘的新治疗方法的临床和放射学结果。本系统审查符合2020年系统审查和荟萃分析的首选报告项目声明。主要结果是栓塞术在CSF-静脉瘘闭塞中的疗效,次要结局包括手术并发症以及临床症状和放射学结果的改善.由77名患者组成的总共9项研究符合纳入标准。直立和/或Valsalva头痛是最常见的症状。患者的平均年龄为57±8.9岁,女性占59.7%(46/77)。65例(84.4%)患者报告症状完全缓解或显著改善。伯尔尼的比分,头痛影响测试-6和患者总体变化印象量表显示放射学发现和患者生活质量的显着改善。按照程序,22例患者(28.6%)经历了反跳性颅内高压,27例患者(35.1%)在栓塞部位出现了短暂的局部疼痛。我们的研究表明,血管内栓塞是SIH患者CSF-静脉瘘安全有效的治疗方法,提供临床症状和放射学发现的完全解决或显着改善,以及对患者生活质量的积极影响。
    Cerebrospinal fluid (CSF)-venous fistula can cause spontaneous intracranial hypotension (SIH) and poses a significant diagnostic and management challenge. This study aims to provide a comprehensive overview of the clinical and radiological outcomes of endovascular embolization as a novel treatment approach for CSF-venous fistula in patients with SIH. This systematic review adheres to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 statement. The primary outcome was the efficacy of the embolization procedure in occlusion of the CSF-venous fistula, and secondary outcomes included procedural complications and improvement of clinical symptoms and radiological findings. A total of nine studies consisting of 77 patients met the inclusion criteria. Orthostatic and/or Valsalva headache was the most common symptom. The mean age of the patients was 57 ± 8.9 years, and females accounted for 59.7% (46/77) of the cases. Sixty-five (84.4%) patients reported complete resolution or significant improvement in symptoms. The Bern score, Headache Impact Test-6, and the Patient Global Impression of Change scales demonstrated significant improvements in radiological findings and patients\' quality of life. Following the procedure, 22 patients (28.6%) experienced rebound intracranial hypertension and 27 patients (35.1%) had transient local pain at the site of the embolization. Our study showed that endovascular embolization is a safe and effective treatment for CSF-venous fistula in patients with SIH, providing complete resolution or significant improvement of clinical symptoms and radiological findings, and positive impacts on patients\' quality of life.
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  • 文章类型: Case Reports
    由于发病率低,小儿脑和脊柱的脑动静脉分流具有挑战性,变量表示,以及与遗传综合征的关联。关于他们的自然历史的知识来自小系列的评论。为了更好地了解自然历史和干预作用,介绍了两个案例,然后回顾了文献。在第一种情况下,1例既往有颅内瘘破裂出血史的婴儿返回择期栓塞治疗2周后发现自发形成血栓的第二个静脉瘘.在第二种情况下,一个患有脊椎-脊椎瘘的5岁孩子,确定了心脏杂音的工作,并记录了诊断血管造影,6周后进行选择性栓塞,确定自发性血栓形成。在回顾有关小儿单孔脑和脊柱瘘的文献时,作者提供了一些形态学考虑因素,以确定哪些高流量瘘可能发生自发性血栓形成,从而降低与幼儿干预相关的潜在不必要风险.
    Pediatric pial arteriovenous shunts in the brain and spine are challenging to understand because of low incidence, variable presentation, and associations with genetic syndromes. What is known about their natural history comes from reviews of small series. To better understand the natural history and role for intervention, two cases are presented followed by a review of the literature. In the first case, an infant with a prior history of intracranial hemorrhage from a ruptured pial fistula returns for elective embolization for a second pial fistula which was found to be spontaneously thrombosed 2 weeks later. In the second case, a 5-year-old with a vertebro-vertebral fistula, identified on work up for a heart murmur and documented with diagnostic angiography, is brought for elective embolization 6 weeks later where spontaneous thrombosis is identified. In reviewing the literature on pediatric single-hole fistulae of the brain and spine, the authors offer some morphologic considerations for identifying which high-flow fistulae may undergo spontaneous thrombosis to decrease the potentially unnecessary risk associated with interventions in small children.
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  • 文章类型: Review
    背景:动静脉瘘是动脉和静脉之间的异常连通。创伤性阴茎动脉自发性瘘是一种罕见的并发症,已被描述为勃起功能障碍的原因。阴茎外伤后勃起功能障碍患者的临床评估包括全面的病史,体检,血管评估,和其他补充考试。治疗包括血管内栓塞,手术结扎,或两种技术的组合。
    方法:一名40岁男子出现勃起功能障碍,几个月前遭受钝性创伤后,该患者一直存在。他报告了勃起时间短和阴茎肿胀不足的问题。由于高度怀疑动静脉瘘,他接受了血管造影检查,这证实了阴部血管之间异常连接的诊断。患者采用线圈栓塞技术治疗,经血管内治疗后症状成功缓解。
    结论:创伤后动脉自发性瘘的出现是一种罕见的并发症,几乎没有文献报道。血管内技术的快速发展,我们使用栓塞剂来阻断异常的血流,允许安全,有效且侵入性较小的替代手术。我们的病例表明,由于症状得到解决,血管内途径是创伤后动脉自发性瘘的成功治疗方法。干预后勃起功能恢复正常。
    BACKGROUND: An arteriovenous fistula is an abnormal communication between an artery and a vein. Traumatic penile arteriospongious fistula is a rare complication and has been described as a cause of erectile dysfunction. Clinical evaluation of patients with erectile dysfunction after penile trauma includes a thorough history, physical examination, vascular assessment, and other complementary exams. Treatment consists of endovascular embolization, surgical ligation, or a combination of both techniques.
    METHODS: A 40-year-old man presented with erectile dysfunction that had persisted since suffering blunt trauma a few months ago. He reported problems with short duration of erection and insufficient penile tumescence. Due to high suspicion of an arteriovenous fistula, he was referred to angiography, which confirmed the diagnosis of an abnormal connection between the pudendal vessels. The patient was treated with the coil embolization technique and the symptoms were successfully resolved after endovascular treatment.
    CONCLUSIONS: The appearance of a post-traumatic arteriospongious fistula is a rare complication with almost non-existent literature reported. Rapid development in endovascular techniques, in which we use embolic agents to block anomalous blood flow, has allowed safe, effective and less invasive alternative to surgery. Our case demonstrates that endovascular approach is a successful treatment for post-traumatic arteriospongious fistula since the symptoms were resolved, and normal erectile function was regained after the intervention.
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  • 文章类型: Journal Article
    盆腔静脉疾病(PeVD),以前已知的各种不精确的术语,包括盆腔淤血综合征,历史上一直被低估为慢性盆腔疼痛(CPP)的原因,与生活质量下降相关的重大健康问题。然而,该领域的进展有助于提高与PeVD有关的定义的清晰度,以及PeVD检查和治疗算法的发展伴随着对盆腔静脉储库原因和相关症状的新见解。目前,卵巢和盆腔静脉栓塞,以及髂总静脉压迫的血管内支架置入术,两者都应被视为PeVD的管理选项。两种治疗方法都被证明对静脉来源的CPP患者是安全有效的,不管年龄。由于有限的前瞻性随机数据和对驱动成功结果的因素的不断发展的理解,目前对PeVD的治疗方案表现出明显的异质性;预计即将进行的临床试验将提高对静脉起源的CPP以及PeVD管理算法的理解。本AJR专家小组叙事审查提供了与PeVD有关的当代更新,汇总实体的当前分类,诊断检查,血管内治疗,持续或复发症状的管理,以及未来的研究方向。
    Pelvic venous disorders (PeVD), previously known by various imprecise terms including pelvic congestion syndrome, have historically been underdiagnosed as a cause of chronic pelvic pain (CPP), a significant health problem associated with reduced quality of life. However, progress in the field has helped to provide heightened clarity with respect to definitions relating to PeVD, and evolution in algorithms for PeVD workup and treatment has been accompanied by new insights into the causes of a pelvic venous reservoir and associated symptoms. Ovarian and pelvic vein embolization, as well as endovascular stenting of common iliac vein compression, should be considered as management options for PeVD. Both treatments have been shown to be safe and effective for patients with CPP of venous origin, regardless of age. Current therapeutic protocols for PeVD exhibit significant heterogeneity owing to limited prospective randomized data and evolving understanding of the factors driving successful outcomes; forthcoming clinical trials are anticipated to improve understanding of CPP of venous origin as well as algorithms for PeVD management. This Expert Panel Narrative Review provides a contemporary update relating to PeVD, summarizing the entity\'s current classification, diagnostic workup, endovascular treatments, management of persistent or recurrent symptoms, and future research directions.
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  • 文章类型: Review
    目的:肝动静脉瘘(HAPF)是肝外伤的罕见并发症,伤后数月至数年可表现为腹痛和门脉高压后遗症。这项研究的目的是介绍我们繁忙的城市创伤中心的HAPF病例,并提出管理建议。
    方法:回顾性分析了2019年1月至2022年10月期间的127例高度穿透性肝损伤(美国创伤外科协会[AAST]-IV-V级)患者。从我们经ACS验证的成人1级创伤中心,腹部创伤后有5例患者被确定为急性肝动静脉瘘。描述了整体手术管理的机构经验,并结合当前文献进行了回顾。
    结果:我们的4例患者出现失血性休克,需要紧急手术干预。第一例患者进行了HAPF的术后血管造影和线圈栓塞。2至4例患者接受了损伤控制性剖腹手术,暂时关闭腹部,然后用明胶海绵颗粒(明胶海绵)或明胶海绵/氰基丙烯酸正丁酯联合进行术后动脉栓塞。最终患者在鉴定HAPF后直接进行血管造影和明胶海绵栓塞。所有5例患者在随访影像学检查中均有HAPF的消退,并继续对外伤进行后处理。
    结论:肝动静脉瘘可表现为肝损伤的并发症,并表现为显著的血流动力学异常。尽管在几乎所有病例中都需要手术干预以实现出血控制,使用现代血管内技术成功实现了在高度肝损伤背景下HAPF的管理。必须对此类损伤采取多学科方法,以优化创伤后急性环境中的护理。
    OBJECTIVE: Hepatic arterioportal fistula (HAPF) is an uncommon complication of hepatic trauma, which can manifest with abdominal pain and the sequelae of portal hypertension months to years after injury. The purpose of this study is to present cases of HAPF from our busy urban trauma center and make recommendations for management.
    METHODS: One hundred and twenty-seven patients with high-grade penetrating liver injuries (American Association for the Surgery of Trauma [AAST] - Grades IV-V) between January 2019 and October 2022 were retrospectively reviewed. Five patients were identified with an acute hepatic arterioportal fistula following abdominal trauma from our ACS-verified adult Level 1 trauma center. Institutional experience with overall surgical management is described and reviewed with the current literature.
    RESULTS: Four of our patients presented in hemorrhagic shock requiring emergent operative intervention. The first patient had postoperative angiography and coil embolization of the HAPF. Patients 2 through 4 underwent damage control laparotomy with temporary abdominal closure followed by postoperative transarterial embolization with gelatin sponge particles (Gelfoam) or combined Gelfoam/n-butyl cyanoacrylate. The final patient went directly for angiography and Gelfoam embolization after identification of the HAPF. All 5 patients had resolution of HAPF on follow-up imaging with continued post management for traumatic injuries.
    CONCLUSIONS: Hepatic arterioportal fistula can present as a complication of hepatic injury and manifest with significant hemodynamic aberrations. Although surgical intervention was required to achieve hemorrhage control in almost all cases, management of HAPF in the setting of high-grade liver injuries was achieved successfully with modern endovascular techniques. A multidisciplinary approach to such injuries is necessary to optimize care in the acute setting following traumatic injury.
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  • 文章类型: Journal Article
    作为脑出血的重要原因,癫痫发作,和神经衰退,脑动静脉畸形(bAVM)是一组罕见的复杂血管病变,对患者的生活质量具有破坏性影响。尽管科学界的共同努力提高了我们对bAVM生物学的理解,确切的机制仍在阐明。此外,直到今天,由于bAVM的高度异质性以及缺乏评估和比较研究带来的客观数据的缺乏,对于这种危及生命的动态疾病的治疗尚无明确共识.因此,患者往往无法获得最佳治疗。血管内栓塞是多学科bAVM管理的固有部分,可用于各种临床情况,每个人都有不同的目标。训练有素的神经介入中心精通治疗小于3厘米的bAVM;位于非雄辩区域的表面;较大,和不那么曲折的喂养动脉。
    As a significant cause of intracerebral hemorrhages, seizures, and neurological decline, brain arteriovenous malformations (bAVMs) are a rare group of complex vascular lesions with devastating implications for patients\' quality of life. Although the concerted effort of the scientific community has improved our understanding of bAVM biology, the exact mechanism continues to be elucidated. Furthermore, to this day, due to the high heterogeneity of bAVMs as well as the lack of objective data brought by the lack of evaluative and comparative studies, there is no clear consensus on the treatment of this life-threatening and dynamic disease. As a consequence, patients often fall short of obtaining the optimal treatment. Endovascular embolization is an inherent part of multidisciplinary bAVM management that can be used in various clinical scenarios, each with different objectives. Well-trained neuro-interventional centers are proficient at curing bAVMs that are smaller than 3 cm; are located superficially in noneloquent areas; and have fewer, larger, and less tortuous feeding arteries. The transvenous approach is an emerging effective and safe technique that potentially offers a chance to cure previously untreatable bAVMs. This review provides the state of the art in all aspects of endovascular embolization in the management of bAVMs.
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  • 文章类型: Journal Article
    简介急性上消化道出血(UGIB)是一种医疗紧急情况,也是全球住院的常见原因。传统上,以复苏和内窥镜介入作为一线治疗。在这项研究中,我们评估了经导管动脉栓塞术(TAE)在UGIB未控制患者内镜介入治疗后的辅助作用.材料和方法对2018年至2021年在BronxCare卫生系统中需要UGIBTAE的患者进行了回顾性图表回顾,该患者未受到内镜干预的控制。研究中包括年龄超过18岁并在研究期间需要TAE的患者。对患者的人口统计数据进行了患者图表审查,合并症,医院课程,影像学发现,食管胃十二指肠镜检查结果和干预,介入放射学干预和临床结果。结果共纳入10例患者。大多数患者是男性。10例患者经导管心房栓塞均成功。在七名患者中使用线圈,而在两名患者中使用微粒聚乙烯醇500微米颗粒,在两名患者中使用血管塞。在10个病人中,四个在医院期间过期。没有患者继发于UGIB而死亡。其中三名患者因严重败血症并继发于肺炎的败血症性休克而死亡,而一名患者因支气管内病变继发的肺塌陷而死于呼吸衰竭。结论难治性急性UGIB与显著的发病率和死亡率相关。TAE是一种微创措施,应在常规内镜治疗难以治疗的UGIB早期考虑。我们的病例强调了TAE在内镜介入后难治性UGIB患者中的重要性。
    Introduction Acute upper gastrointestinal bleeding (UGIB) is a medical emergency and a common cause of hospital admissions worldwide. It has traditionally been treated with resuscitation and endoscopic intervention as the first-line therapy. In this study, we assessed the adjunctive role of transcatheter arterial embolization (TAE) in patients with uncontrolled UGIB after an endoscopic intervention. Material and methods A retrospective chart review of patients requiring TAE of UGIB which was not controlled by endoscopic intervention in BronxCare Health System from 2018 to 2021 was done. Patients who were more than 18 years of age and required TAE during the time period of the study were included in the study. Patients\' charts were reviewed for patients\' demographics, comorbidities, hospital course, imaging findings, esophagogastroduodenoscopy findings and intervention, and interventional radiology intervention and clinical outcome. Results A total of 10 patients were included in the study. A majority of the patients were male. Transcatheter atrial embolization was successful in all the 10 patients. Coils were used in seven patients while particulate polyvinyl alcohol 500 micron particle was used in two patients and vascular plug was used in two patients. Out of the 10 patients, four expired during the hospital course. None of the patients died secondary to UGIB. Three of the patients expired due to severe sepsis with septic shock secondary to pneumonia while one patient died because of respiratory failure due to lung collapse secondary to endobronchial lesion. Conclusion Refractory acute UGIB is associated with significant morbidity and mortality. TAE is a minimally invasive measure that should be considered early in the treatment of UGIB which is refractory to conventional endoscopic management. Our case highlights the importance of TAE in a patient with refractory UGIB after endoscopic intervention.
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  • 文章类型: Journal Article
    背景:孤立的真菌性髂内动脉动脉瘤很少见,这些患者的治疗可能很复杂。
    方法:我们介绍了一例罕见的由肠炎沙门氏菌引起的真菌性右髂内动脉瘤。这是分阶段管理的-静脉注射抗生素,然后血管内支架置入术和栓塞术,和随后的残余收集经皮引流。患者无围手术期并发症,并且在术后超过18个月时仍保持良好状态,没有支架感染的证据。
    结论:在治疗真菌性髂内动脉瘤时,结合血管内动脉瘤修复和经皮引流的微创方法是一种可行的选择。
    BACKGROUND: Isolated mycotic internal iliac artery aneurysms are rare and management of these patients can be complex.
    METHODS: We present a rare case of isolated mycotic right internal iliac artery aneurysm caused by Salmonella enteritides. This was managed in stages - with intravenous antibiotics, followed by endovascular stenting and embolization, and subsequent percutaneous drainage of the remnant collection. The patient had no perioperative complications, and has remained well at more than 18 months post-operatively with no evidence of stent infection.
    CONCLUSIONS: A minimally-invasive approach combining endovascular aneurysm repair and percutaneous drainage is a viable option in the management of a mycotic internal iliac artery aneurysm.
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