单氟兰(L.)DC。(syn.Leuzeauniflora(L.)Holub)是菊科(菊科)科的一种植物物种,广泛用于中国的亚洲传统药物中,西伯利亚,和蒙古作为抗炎和兴奋剂的补救措施。目前,R.uniflorum对化学家具有科学意义,生物学家,和药理学家,这篇综述包括1991年至2022年的科学文献中的信息。对R.uniflorum的化学多样性的研究揭示了225种化合物的存在,包括倍半萜,蜕皮类固醇,三萜,固醇,噻吩,羟基肉桂酸酯,黄酮类化合物,木脂素,核苷和维生素,烷烃,脂肪酸,和碳水化合物。研究最多的物质组是酚类(76种化合物)和三萜类(69种化合物)。有关所选化合物的色谱分析方法的信息,以及一氟菌各个器官中某些成分的定量含量,在这项工作中进行了总结。研究表明,单氟菌的提取物和部分化合物具有广泛的生物活性,包括消炎药,抗肿瘤,免疫刺激,抗焦虑药,压力保护,行动保护,抗缺氧,合成代谢,保肝,抑制PPARγ受体,抗动脉粥样硬化,和降血脂。已发表的关于R.uniflorum的代谢物和生物活性的研究不包括提取物和纯化合物的临床研究;因此,需要对这种传统药用植物进行准确的研究。
Rhaponticum uniflorum (L.) DC. (syn. Leuzea uniflora (L.) Holub) is a plant species of the Compositae (Asteraceae) family that is widely used in Asian traditional medicines in China, Siberia, and Mongolia as an anti-inflammatory and stimulant remedy. Currently, R. uniflorum is of scientific interest to chemists, biologists, and pharmacologists, and this
review includes information from the scientific literature from 1991 to 2022. The study of the chemodiversity of R. uniflorum revealed the presence of 225 compounds, including sesquiterpenes,
ecdysteroids, triterpenes, sterols, thiophenes, hydroxycinnamates, flavonoids, lignans, nucleosides and vitamins, alkanes, fatty acids, and carbohydrates. The most studied groups of substances are phenolics (76 compounds) and triterpenoids (69 compounds). Information on the methods of chromatographic analysis of selected compounds, as well as on the quantitative content of some components in various organs of R. uniflorum, is summarized in this work. It has been shown that the extracts and some compounds of R. uniflorum have a wide range of biological activities, including anti-inflammatory, antitumor, immunostimulatory, anxiolytic, stress-protective, actoprotective, antihypoxic, anabolic, hepatoprotective, inhibition of PPARγ receptors, anti-atherosclerotic, and hypolipidemic. Published research on the metabolites and bioactivity of R. uniflorum does not include clinical studies of extracts and pure compounds; therefore, an accurate study of this traditional medicinal plant is needed.