背景:本研究将研究氧化苦参碱对人肝癌Bel-7404细胞(HLCBC)增殖的影响。
方法:本研究将搜索PUBMED中可用的电子书目数据库,EMBASE,科克伦图书馆,Scopus,护理和相关健康文献的累积指数,中国生物医学,和中国国家知识基础设施。我们尝试搜索从开始到2020年2月29日与HLCBC有关的病例对照研究(CCS)或随机对照研究(RCS),不受语言和发表时间的限制。我们将包括任何关于探索氧化苦参碱对HLCBC增殖的CCS或RCS。我们将通过纽卡斯尔-渥太华量表评估CCS的方法学质量,和RCS通过Cochrane偏差风险工具。将使用ReviewManager5.3软件进行统计分析。
结果:本研究将总结最新的合格研究,以研究氧化苦参碱对HLCBC增殖的影响。
结论:其结果为氧化苦参碱对HLCBC增殖的影响提供了可靠的科学依据。
背景:INPLASY202040026。
BACKGROUND: This study will examine the effects of oxymatrine on the proliferation of human liver cancer Bel-7404 cells (HLCBC).
METHODS: This study will search electronic bibliographic databases available in PUBMED, EMBASE, Cochrane Library, Scopus, Cumulative Index to Nursing and Allied Health Literature, China Biology Medicine, and China National Knowledge Infrastructure. We attempt to search case-controlled studies (CCSs) or randomized controlled studies (RCSs) pertaining to HLCBC from their inception to the February 29, 2020 without limitations of language and publication time. We will include any CCSs or RCSs on exploring oxymatrine on the proliferation of HLCBC. We will assess the methodological quality of CCSs by Newcastle-Ottawa Scale, and RCSs by Cochrane risk of bias tool.
Review Manager 5.3 software will be utilized for statistical analysis.
RESULTS: The current study will summarize most recent eligible studies to investigate the effects of oxymatrine on the proliferation of HLCBC.
CONCLUSIONS: Its results may provide reliable scientific evidence on effects of oxymatrine on the proliferation of HLCBC.
BACKGROUND: INPLASY202040026.