E-liquids

电子液体
  • 文章类型: Journal Article
    背景:接触电子烟液,无论是故意的还是偶然的,可能导致不良事件。这项研究旨在描述向法国毒物控制中心报告的电子液体暴露的患病率和特征。
    方法:回顾了2019年7月1日至2020年12月31日法国毒物控制中心报告的所有电子液体暴露病例。收集了有关患者特征的信息,暴露情况,管理和结果。
    结果:报告了约919例电子液体暴露。年龄从一个月到89岁,平均年龄为16.6±18.6岁,中位年龄为4岁。接触最多的婴儿(0-4岁),占50.7%,3.1%的儿童(5-11岁),5.9%的青少年(12-17岁),40.1%的个案涉及成人。大多数病例是偶然的(95.0%)。故意暴露(4.9%)主要在12岁以上的患者中观察到(P<0.001)。73.7%的病例的暴露途径是摄入。总共455次暴露没有与中毒有关的症状或体征。电子液体中的高尼古丁浓度与医院管理的增加有关(赔率比从1.77到2.60)。
    结论:非自愿接触电子液体更常见于5岁以下的儿童,主要是通过摄入。与有意摄取不同,无意摄入很少导致严重不良事件。这些发现强调了持续监测以防止此类暴露和相关伤害的重要性,强调需要对这些产品进行有效监管。
    Exposure to e-cigarette liquids, whether intentional or accidental, might lead to adverse events. This study aimed to describe the prevalence and characteristics of exposures to e-liquids reported to French Poison Control Centers.
    All e-liquids exposure cases reported to French Poison Control Centers from July 1, 2019, to December 31, 2020, were reviewed. Information was collected about the patient\'s characteristics, exposure circumstances, management and outcome.
    About 919 cases of exposure to e-liquids were reported. Ages ranged from one month to 89 years, with a mean age of 16.6 ± 18.6 years and a median age of 4 years. The highest number of exposures-50.7%-concerned infants (0-4 years), 3.1% children (5-11 years), 5.9% adolescents (12-17 years), and 40.1% of cases concerned adults. The majority of cases were accidental (95.0%). Intentional exposures (4.9%) were mainly observed in patients older than 12 years of age (P < 0.001). The route of exposure was ingestion in 73.7% of the cases. A total of 455 exposures showed no symptoms or signs related to poisoning. High nicotine concentration in e-liquids was associated with an increase in hospital management (Odds-ratio from 1.77 to 2.60).
    Involuntary exposures to e-liquids occurred more often in children under the age of five, mainly by ingestion. Unlike intentional ingestions, unintentional ingestions rarely resulted in severe adverse events. These findings highlight the importance of ongoing surveillance to prevent such exposures and associated injuries, emphasizing the need for effective regulation of these products.
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