■目前,脊髓电刺激对脑外伤后严重意识障碍患者的使用仍然有限,而且长期的后续研究甚至更少。迄今为止,很少有报道使用近红外光谱法评估脊髓电刺激治疗严重意识障碍的临床效果和最佳参数。本报告描述了一例脑外伤后严重意识障碍的患者,该患者接受了脊髓电刺激植入。采用先进的近红外光谱法监测和评估术后疗效。该病例报告的结果将为严重意识障碍的临床治疗提供参考。
■一名诊断为脑外伤后意识严重障碍的患者出现昏迷和缺乏自愿活动的症状。治疗方案包括常规方法(药物结合康复训练)和脊髓电刺激参数的调整。使用高级功能近红外光谱(fNIRS)来探索脑功能连接强度的变化并评估临床疗效。
■常规治疗和连续修改脊髓电刺激参数的整合,结合fNIRS监测,结果表明,常规治疗和脊髓电刺激对增加脑功能强度连接显示出积极作用。格拉斯哥昏迷量表(GCS)评分较基线显著改善。在4.5V振幅的脊髓刺激设置下观察到最佳结果,210μs脉冲宽度,和70Hz频率,从8:00-20:00以15分钟开15分钟关的循环模式运行,意识的改善非常明显。
■脑外伤后出现严重意识障碍的患者恢复缓慢。常规治疗联合脊髓电刺激能改善患者意识障碍程度,促进病情恢复。
UNASSIGNED: Currently, the use of spinal cord electrical stimulations for patients with severe disorders of consciousness after traumatic brain injury remains limited, and long-term follow-up studies are even scarcer. To date, there have been few
reports using near-infrared spectroscopy to evaluate the clinical effects and optimal parameters of spinal cord electrical stimulation for severe consciousness disorders. This report describes a
case of a patient with severe disturbance of consciousness after traumatic brain injury who underwent spinal cord electrical stimulation implantation. Advanced near-infrared spectroscopy was employed to monitor and evaluate postoperative efficacy. The findings of this
case report will provide a reference for the clinical treatment of severe consciousness disturbances.
UNASSIGNED: A patient diagnosed with a severe disturbance of consciousness following traumatic brain injury presented symptoms of coma and lack of voluntary activity. The treatment regimen included conventional approaches (medication combined with rehabilitation training) and adjustments to the spinal cord electrical stimulation parameters. Advanced functional near-infrared spectroscopy (fNIRS) was used to explore changes in brain functional connectivity strength and assess clinical efficacy.
UNASSIGNED: The integration of conventional treatment and continuous modification of spinal cord electrical stimulation parameters, combined with fNIRS monitoring, demonstrated that conventional treatment and spinal cord electrical stimulation displayed a positive effect on increasing brain functional strength connection. The Glasgow Coma Scale(GCS) score significantly improved from the baseline. Optimal results were observed with spinal cord stimulation settings at 4.5 V amplitude, 210 μs pulse width, and 70 Hz frequency, operating from 8:00-20:00 in a cycling mode of 15 min on and 15 min off, where improvements in consciousness were markedly evident.
UNASSIGNED: Patients with severe disturbances of consciousness after traumatic brain injury recover slowly. Conventional treatment combined with spinal cord electrical stimulation can improve the degree of disturbance of consciousness and promote recovery from the condition.