Curettage

刮宫术
  • 文章类型: Case Reports
    动脉瘤性骨囊肿(ABC)是骨骼系统的良性溶解性骨肿瘤,但未知来源的局部破坏性病变。它通常发生在儿童时期,通常涉及长骨的干phy端区域;因此,它在跟骨中的定位仍然很少见;在我们的案例中,它的非典型表现使其引人注目。
    方法:我们描述了一个患有慢性足跟痛的年轻患者,临床检查发现触诊时肿胀和疼痛。进行了完整的放射学评估,显示跟骨内有孤立性和扩张性溶骨性病变。治疗包括肿瘤刮治和同种异体移植和骨水泥重建。活检报告与ABC一致。术后18个月的随访具有良好的放射临床演变和无复发。
    ABCs是良性囊性扩张性肿瘤,具有反应性,局部破坏性和充满血液的,它们在跟骨发生的报告病例仅占总报告病例的1.6%。Talalgia是与肿胀相关的最常见体征。MRI上的液位图像是这些病变的病理标志,但金标准诊断仍然是组织学。他们的治疗是基于刮治-通过移植填充。
    结论:刮治联合移植使效果良好,并提高了生活质量。
    UNASSIGNED: Aneurysmal bone cyst (ABC) is a benign lytic bone tumor of the skeletal system but locally destructive lesion of unknown origin. It often occurs in childhood and usually involves the metaphyseal region of long bones; thus, its localisation in the calcaneum remains rare; its atypical presentation in our case makes it remarkable.
    METHODS: We describe a case of a young patient who suffered from chronic heel pain, in whom the clinical examination finds swelling and pain on palpation. A complete radiological assessment was carried out, which revealed a solitary and expansive osteolytic lesion within the calcaneus. Treatment included tumor curettage and reconstruction with allograft and cement. The biopsy report was consistent with an ABC. The postoperative follow-up at 18 months was marked by a good radio-clinical evolution and no recurrence.
    UNASSIGNED: ABCs are benign cystic expansive tumors that are reactive, locally destructive and blood-filled, their occurrence in the calcaneus has been reported in only 1.6 % of total reported cases. Talalgia is the most frequent sign associated with swelling. Liquid-liquid level images on MRI is a pathognomonic sign of these lesions but the gold standard diagnosis remains histology. Their treatment is based on curettage - filling by grafting.
    CONCLUSIONS: Curettage combined graft makes results butter and improves the quality of life.
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  • 文章类型: Systematic Review
    背景:骨巨细胞瘤(GCTB)的理想治疗方法仍然存在争议。在病灶内刮除后已引入各种手术佐剂以提高局部控制率。然而,相关研究的结果不一致,尚未达成共识。这项研究的目的是确定术中辅助治疗对减少GCTB的复发有效。
    方法:我们对PubMed和Embase电子数据库中发表的文章进行了系统评价和荟萃分析,这些文章评估了有或没有各种手术辅助的病灶内刮治术后GCTB的复发率。两位作者独立评估了所有出版物。使用Stata/MP(17.0版,StataCorpLLC,TX,美国)和审查经理(RevMan,版本5.4.1,Cochrane协作,2020)。集合风险比(RR)用于分析,P值小于0.05被认为具有统计学意义。
    结果:本分析包括24项涉及2,579名患者的研究。有或没有高速毛刺(HSB)治疗的患者的总复发率为11.9%(26/218)和47.7%(92/193),分别。肿瘤复发的合并RR为0.33(95%CI:0.22至0.49,P<0.001)。同时,使用或不使用化学佐剂治疗的患者的总复发率为23.5%(77/328)和26.1%(73/280),分别,合并RR为0.84(95%CI:0.63至1.10,P=0.89)。此外,使用或不使用聚甲基丙烯酸甲酯(PMMA)治疗的患者的总复发率为20.4%(205/1,006)和33.4%(314/939),分别,合并RR为0.59(95%CI:0.50至0.69,P<0.001)。
    结论:术中应用HSB或PMMA具有额外的抗肿瘤作用,而使用苯酚或H2O2不能产生任何显著差异(PROSPERO:CRD42022344262)。
    BACKGROUND: The ideal treatment for giant cell tumor of bone (GCTB) is still controversial. Various surgical adjuvants have been introduced following intralesional curettage to improve local control rates. However, findings from relevant studies are inconsistent, and no consensus has been reached. The purpose of this study is to determine what intraoperative adjuvant is effective in decreasing the recurrence of GCTB.
    METHODS: We performed a systematic review and meta-analysis of articles published in the PubMed and Embase electronic databases which assessed the recurrence rate of GCTB following intralesional curettage with or without various surgical adjuvants. Two authors independently evaluated all publications. Meta-analysis was performed with Stata/MP (Version 17.0, StataCorp LLC, TX, USA) and Review Manager (RevMan, Version 5.4.1, The Cochrane Collaboration, 2020). Pooled risk ratio (RR) was used for analysis, with P values less than 0.05 considered statistically significant.
    RESULTS: Twenty-four studies involving 2,579 patients were included in this analysis. The overall recurrence rates for patients treated with or without high-speed burring (HSB) are 11.9% (26/218) and 47.7% (92/193), respectively. The pooled RR for tumor recurrence is 0.33 (95% CI: 0.22 to 0.49, P<0.001). In the meanwhile, the overall recurrence rates for patients treated with or without chemical adjuvants are 23.5% (77/328) and 26.1% (73/280), respectively, with a pooled RR of 0.84 (95% CI: 0.63 to 1.10, P=0.89). Additionally, the overall recurrence rates for patients treated with or without polymethyl methacrylate (PMMA) are 20.4% (205/1,006) and 33.4% (314/939), respectively, with a pooled RR of 0.59 (95% CI: 0.50 to 0.69, P<0.001).
    CONCLUSIONS: Intraoperative application of HSB or PMMA has an additional antitumor effect, while the use of phenol or H2O2 fails to make any significant difference (PROSPERO: CRD42022344262).
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  • 文章类型: Journal Article
    桡骨远端巨细胞瘤(GCT)的治疗仍然具有挑战性,而最佳方法仍然是一个争论的问题。本系统评价和荟萃分析旨在比较长期刮宫术和广泛切除术的结果。治疗的支柱。
    Medline(通过PubMed),科克伦图书馆,WebofScience,谷歌学者,ClinicalTrials.gov,我们在Embase数据库中搜索了比较研究,这些研究评估了截至2023年4月桡骨远端GCT患者的长期刮宫联合辅助治疗和广泛切除联合重建治疗.收集数据并分析局部复发率,转移,整体并发症,和功能结果。纽卡斯尔-渥太华量表用于评估每项研究中的偏倚风险。
    纳入并分析了15项研究(n=373例患者)。进行刮宫的患者更有可能发生复发(风险比[RR]=3.02[95%置信区间;CI,1.87-4.89],P<.01),显示并发症较少(RR=0.32[95%CI,0.21-0.49],P<.01),并显示出视觉模拟量的较大改善和手臂的较低残疾,肩膀,和手评分(P<.00001)比接受广泛切除的患者。在转移方面没有发现显着差异(RR=1.03[95%CI,0.38-2.78],P=.95)。
    关于桡骨远端GCT的手术入路,与大范围切除重建相比,辅助治疗的刮宫复发的可能性更高。然而,刮宫法可显著降低手术并发症的发生率,疼痛评分降低,与切除组相比,功能结局更好。
    UNASSIGNED: The management of distal radius giant cell tumors (GCTs) remains challenging, and the optimal approach is still a matter of debate. This systematic review and meta-analysis aimed to compare the outcomes of extended curettage and wide resection, the mainstays of treatment.
    UNASSIGNED: Medline (via PubMed), Cochrane Library, Web of Science, Google Scholar, ClinicalTrials.gov, and Embase databases were searched for comparative studies that assessed extended curettage with adjuvant therapy and wide resection with reconstruction in patients with GCTs of the distal radius up to April 2023. Data were collected and analyzed on rates of local recurrence, metastasis, overall complications, and functional outcomes. The Newcastle-Ottawa scale was used to appraise the risk of bias within each study.
    UNASSIGNED: Fifteen studies (n = 373 patients) were included and analyzed. Patients who underwent curettage were more likely to develop recurrence (risk ratio [RR] = 3.02 [95% confidence interval; CI, 1.87-4.89], P < .01), showed fewer complications (RR = 0.32 [95% CI, 0.21-0.49], P < .01), and showed greater improvement in Visual Analog Scale and lower Disabilities of the Arm, Shoulder, and Hand scores (P < .00001) than those who underwent wide resection. No significant difference was found regarding metastasis (RR = 1.03 [95% CI, 0.38-2.78], P = .95).
    UNASSIGNED: Regarding the surgical approach to GCT of the distal radius, curettage with adjuvant therapy was associated with a higher likelihood of recurrence compared with wide resection with reconstruction. Nevertheless, the curettage approach resulted in significantly lower rates of operative complications, decreased pain scores, and better functional outcomes in comparison to the resection group.
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  • 文章类型: Journal Article
    疣是由人乳头瘤病毒(HPV)感染引起的,可累及皮肤和粘膜的多个部位,其中甲周和甲下疣是最难治疗的。指甲周围或指甲下疣是在指甲周围或指甲下生长的寻常疣,破坏和变形指甲和甲床。目前,液氮冷冻疗法和CO2激光通常用于治疗。临床上,很少有医生常规使用光动力疗法(PDT)来治疗病毒性疣.我们使用PDT结合液氮冷冻疗法和刮宫术成功治疗了1例顽固性甲周和甲下疣。
    Warts are caused by human papillomavirus (HPV) infection and can involve multiple parts of skin and mucosa, of which periungual and subungual warts are the most difficult to treat. Periungual or subungual wart is verruca vulgaris growing around or under the fingernail, destroying and deforming the nail and nail bed. Currently, liquid nitrogen cryotherapy and CO2 laser are often used for the treatment. Clinically, few doctors routinely use photodynamic therapy (PDT) to treat viral warts. We used PDT combined with liquid nitrogen cryotherapy and curettage to successfully treat a case of intractable periungual and subungual warts.
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  • 文章类型: Journal Article
    巨细胞瘤(GCT)是具有侵袭性潜力的良性肿瘤,会破坏局部骨结构,这在关节周围位置尤其成问题。我们的目的是评估接受切除而不进行重建的尺骨远端GCT患者的预后。
    该研究包括21例尺骨远端GCT患者,这些患者接受了切除而不进行重建。有12名男性和9名女性,平均年龄30.4岁(范围14-45岁)。患者平均随访时间为4.4年,至少随访两年。
    疼痛的肿胀是所有病例的表现。19例患者为Campanacci3级,2例患者为Campanacci2级。尺骨远端的平均切除长度为6.8cm(范围4-10)cm。肌肉骨骼肿瘤协会评分(MSTS)为26.1。(范围22-28)。受影响的手的握力平均降低了10.5%。(范围0%-16%)。两名患者在就诊时患有多中心疾病,没有一例在就诊时患有病理性骨折。1例局部复发,经手术治疗。
    根据目前的研究,尺骨远端GCT,对于Campanacci2级和3级肿瘤,推荐不进行重建的整块切除作为一种有价值的治疗选择.切除尺骨远端而不进行重建可获得出色的功能结果,与前臂旋转运动和手的功能保存。根据文献综述,这是最大的GCTUlna系列,我们建议对该主题进行多中心和比较研究。
    UNASSIGNED: Giant Cell Tumours (GCT) are benign tumours with aggressive potential that disrupt the local bony architecture, which can be especially problematic in peri-articular locations. Our aim was to assess the outcomes of patients with GCT of the distal ulna who were treated by resection without reconstruction.
    UNASSIGNED: The study included 21 patients with distal ulna GCT that were treated with resection without reconstruction. There were 12 males and 9 females, with a mean age of 30.4years (range 14-45 years). The patients mean follow-up period was 4.4 years, with a two-year minimum follow-up.
    UNASSIGNED: Painful swelling was the presenting symtom in all cases. Nineteen patients had Campanacci grade 3 and two had Campanacci grade 2. The mean resected length of the distal ulna was 6.8 cm (range 4-10) cm. The Musculoskeletal Tumor Society score (MSTS) was 26.1. (range 22-28). Grip strength of the affected hand was reduced by 10.5% on average. (range 0%-16%). Two patients were having multi-centric disease on presentation and none of the cases had pathological fracture on presentation. One case had a local recurrence which was treated with surgery.
    UNASSIGNED: Based on current study, GCT of the distal ulna, en bloc resection without reconstruction can be recommended as a valuable treatment option for Campanacci grades 2 and 3 tumours. Resection of the distal end of the ulna without reconstruction results in excellent functional outcomes, with forearm rotational movement and hand function preserved. According to review of literature this is the largest series of GCT Ulna and we recommend a multicentre and comparitive studies on this topic.
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  • 文章类型: Case Reports
    Brodie的arsal角状脓肿是这种疾病的相对罕见表现。在这项研究中,我们介绍了一例20岁的男性,他患有创伤后Brodie的骨长方体脓肿,在创伤后未治疗三年(用一块锋利的木头进行穿透性损伤)。病人在受伤部位表现出疼痛,一瘸一拐的,而平足X光片显示长方体中有一个小的溶血性空洞区域。磁共振成像显示,在长方体骨的2厘米直径腔中存在脓肿,并且周围足底肌肉组织有慢性炎症。治疗方案包括刮宫,清创术的炎症组织,和抗生素的管理,根据术中收获的培养物,六个星期.在此期间,症状完全解决。
    Brodie\'s abscess of the tarsal cuboid is a relatively rare presentation of this disease. In this study, we present the case of a 20-year-old male with post-traumatic Brodie\'s abscess of the tarsal cuboid that was left untreated for three years after the traumatic episode (penetrating injury with a sharp piece of wood). The patient presented pain over the injured area, limping, while plain foot radiographs showed a small lytic cavitary area in the cuboid. The magnetic resonance imaging revealed the presence of the abscess in a 2-cm diameter cavity in the cuboid bone and chronic inflammation of the surrounding plantar musculature. The treatment regime included curettage of the cavity, debridement of the inflammatory tissues, and administration of antibiotics, according to the cultures harvested intraoperatively, for six weeks. During this period, symptoms completely resolved.
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  • 文章类型: Journal Article
    本研究的目的是确定有关复发性非典型分枝杆菌颈面部淋巴结炎的现有文献,以增强我们对一位特殊患者的认识,该患者在治疗5年后出现刮宫复发,并出现在我们的三级护理中心。
    OVIDMedline,Scopus,和WebofScience。
    进行了文献检索,产生了49篇原创文章,由两名独立评审员进行了两次筛选,结果有14项研究符合Covidence软件数据提取的纳入标准。两名独立评审员提取了非典型分枝杆菌颈面部淋巴结炎复发的数据,并就所有纳入研究的数据点达成共识。
    本研究揭示了关于非典型分枝杆菌淋巴结炎的文献中很少有复发报告。在我们的审查中确定的16项研究包括关于复发的讨论,除了复发率之外,很少详细说明它们的管理。16项研究中有14项提供了其队列的复发率,14个中有11个指定了初始治疗方式,8项研究中只有5项描述了手术的初始治疗,将完全切除和不完全切除的复发率区分开来。纳入研究的平均随访时间为20个月。以前曾报道过一例5年晚期复发病例。
    我们发现很少有关于非典型分枝杆菌颈面部淋巴结炎复发处理的报告。关于手术治疗方式之间复发率的数据很少。我们研究中讨论的病例表明,刮宫治疗有可能出现晚期复发。
    UNASSIGNED: The purpose of this study is to identify existing literature on recurrent atypical mycobacterial cervicofacial lymphadenitis to augment our understanding of a unique patient who presented to our tertiary-care center 5-years posttreatment with recurrence following curettage.
    UNASSIGNED: OVID Medline, Scopus, and Web of Science.
    UNASSIGNED: A literature search was conducted yielding 49 original articles which were screened twice by two independent reviewers resulting in 14 studies meeting inclusion criteria for data extraction using Covidence software. Two independent reviewers extracted data on recurrence of atypical mycobacterial cervicofacial lymphadenitis and consensus was reached on data points from all included studies.
    UNASSIGNED: This study illuminated the paucity of recurrence reporting in the literature regarding atypical mycobacterial lymphadenitis. Sixteen studies identified in our review included discussions on recurrence with few elaborating beyond the rate of recurrence to describe their management. Fourteen out of sixteen studies provided recurrence rates for their cohort, 11 out of 14 specified the initial treatment modality, and only five out of eight studies that described initial treatment with surgery differentiated recurrence rates between complete and incomplete excision. The mean length of follow-up in the included studies was 20 months. There was one previously reported case of late recurrence at 5-years.
    UNASSIGNED: We identified few reports that discussed the management of recurrence of atypical mycobacterial cervicofacial lymphadenitis. There was minimal data on recurrence rates between surgical treatment modalities. The case discussed in our study showcases that treatment with curettage has the potential to present with late recurrence.
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  • 文章类型: Review
    背景:肺栓塞(PE)是心血管死亡的常见原因,其主要获得性危险因素包括术后状态,怀孕,恶性肿瘤,和年龄。我们报告了一例诊断性刮宫后发生的异常子宫出血的PE,有子宫腺肌病和子宫肌瘤病史。
    方法:一名31岁的汉族女性因月经失调被转诊到我院,月经量增加,和严重的贫血。入院后,病人接受了输血治疗,补铁,和促红细胞生成素,第二天进行诊断性刮宫。术后第一天,患者出现肺栓塞,经CT肺动脉造影诊断为呼吸困难和发热,D-二聚体显著升高.
    结果:分子量肝素用于PE2周,治疗2天后,呼吸困难显著缓解,子宫出血未增加;为减少出血,在抗凝治疗1周后,对子宫腺肌病患者给予促性腺激素释放激素激动剂.我们跟踪了6个月,患者无血栓复发,子宫出血好转。
    结论:我们推测肺栓塞的发生与子宫腺肌病密切相关。子宫肌瘤,还有这个病人的刮宫.治疗月经出血和血栓栓塞的存在是具有挑战性的,精心管理是避免治疗矛盾的必要条件。
    BACKGROUND: Pulmonary embolism (PE) is a common cause of cardiovascular death whose major acquired risk factors include postoperative states, pregnancy, malignancy, and age. We report a case of PE that occurred after diagnostic curettage for abnormal uterine bleeding, with a medical history of adenomyosis and hysteromyoma.
    METHODS: A 31-year-old Han Chinese female was referred to our hospital with menstrual disorders, increased menstrual flow, and severe anemia. After admission, the patient was treated with a blood transfusion, iron supplementation, and erythropoietin, and diagnostic curettage was performed the following day. On the first postoperative day, the patient developed pulmonary embolism with dyspnea and fever diagnosed by CT pulmonary angiography and significantly elevated D-dimer.
    RESULTS: Molecular weight heparin was administered for PE for 2 weeks, dyspnea was relieved significantly after 2 days of treatment and the uterine bleeding did not increase; and gonadotropin-releasing hormone agonists were administered for adenomyosis after 1 week of anticoagulant therapy to reduce bleeding. We followed up for 6 months, and the patient had no recurrence of thrombosis and uterine bleeding had improved.
    CONCLUSIONS: We speculate that the occurrence of pulmonary embolism was closely related to adenomyosis, hysteromyoma, and curettage in this patient. Treating the presence of both menstrual bleeding and thromboembolism is challenging, and careful management is necessary to avoid therapeutic contradictions.
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