PDF(Pubmed)
Abstract：
UNASSIGNED: Giant Cell Tumours (GCT) are benign tumours with aggressive potential that disrupt the local bony architecture, which can be especially problematic in peri-articular locations. Our aim was to assess the outcomes of patients with GCT of the distal ulna who were treated by resection without reconstruction.
UNASSIGNED: The study included 21 patients with distal ulna GCT that were treated with resection without reconstruction. There were 12 males and 9 females, with a mean age of 30.4years (range 14-45 years). The patients mean follow-up period was 4.4 years, with a two-year minimum follow-up.
UNASSIGNED: Painful swelling was the presenting symtom in all cases. Nineteen patients had Campanacci grade 3 and two had Campanacci grade 2. The mean resected length of the distal ulna was 6.8 cm (range 4-10) cm. The Musculoskeletal Tumor Society score (MSTS) was 26.1. (range 22-28). Grip strength of the affected hand was reduced by 10.5% on average. (range 0%-16%). Two patients were having multi-centric disease on presentation and none of the cases had pathological fracture on presentation. One case had a local recurrence which was treated with surgery.
UNASSIGNED: Based on current study, GCT of the distal ulna, en bloc resection without reconstruction can be recommended as a valuable treatment option for Campanacci grades 2 and 3 tumours. Resection of the distal end of the ulna without reconstruction results in excellent functional outcomes, with forearm rotational movement and hand function preserved. According to review of literature this is the largest series of GCT Ulna and we recommend a multicentre and comparitive studies on this topic.
UNASSIGNED: The study included 21 patients with distal ulna GCT that were treated with resection without reconstruction. There were 12 males and 9 females, with a mean age of 30.4years (range 14-45 years). The patients mean follow-up period was 4.4 years, with a two-year minimum follow-up.
UNASSIGNED: Painful swelling was the presenting symtom in all cases. Nineteen patients had Campanacci grade 3 and two had Campanacci grade 2. The mean resected length of the distal ulna was 6.8 cm (range 4-10) cm. The Musculoskeletal Tumor Society score (MSTS) was 26.1. (range 22-28). Grip strength of the affected hand was reduced by 10.5% on average. (range 0%-16%). Two patients were having multi-centric disease on presentation and none of the cases had pathological fracture on presentation. One case had a local recurrence which was treated with surgery.
UNASSIGNED: Based on current study, GCT of the distal ulna, en bloc resection without reconstruction can be recommended as a valuable treatment option for Campanacci grades 2 and 3 tumours. Resection of the distal end of the ulna without reconstruction results in excellent functional outcomes, with forearm rotational movement and hand function preserved. According to review of literature this is the largest series of GCT Ulna and we recommend a multicentre and comparitive studies on this topic.
摘要：
■巨细胞瘤（GCT）是具有侵袭性潜力的良性肿瘤，会破坏局部骨结构，这在关节周围位置尤其成问题。我们的目的是评估接受切除而不进行重建的尺骨远端GCT患者的预后。
■该研究包括21例尺骨远端GCT患者，这些患者接受了切除而不进行重建。有12名男性和9名女性，平均年龄30.4岁（范围14-45岁）。患者平均随访时间为4.4年,至少随访两年。
■疼痛的肿胀是所有病例的表现。19例患者为Campanacci3级，2例患者为Campanacci2级。尺骨远端的平均切除长度为6.8cm（范围4-10）cm。肌肉骨骼肿瘤协会评分（MSTS）为26.1。（范围22-28）。受影响的手的握力平均降低了10.5％。（范围0%-16%）。两名患者在就诊时患有多中心疾病，没有一例在就诊时患有病理性骨折。1例局部复发，经手术治疗。
■根据目前的研究，尺骨远端GCT,对于Campanacci2级和3级肿瘤,推荐不进行重建的整块切除作为一种有价值的治疗选择.切除尺骨远端而不进行重建可获得出色的功能结果，与前臂旋转运动和手的功能保存。根据文献综述，这是最大的GCTUlna系列，我们建议对该主题进行多中心和比较研究。
■该研究包括21例尺骨远端GCT患者，这些患者接受了切除而不进行重建。有12名男性和9名女性，平均年龄30.4岁（范围14-45岁）。患者平均随访时间为4.4年,至少随访两年。
■疼痛的肿胀是所有病例的表现。19例患者为Campanacci3级，2例患者为Campanacci2级。尺骨远端的平均切除长度为6.8cm（范围4-10）cm。肌肉骨骼肿瘤协会评分（MSTS）为26.1。（范围22-28）。受影响的手的握力平均降低了10.5％。（范围0%-16%）。两名患者在就诊时患有多中心疾病，没有一例在就诊时患有病理性骨折。1例局部复发，经手术治疗。
■根据目前的研究，尺骨远端GCT,对于Campanacci2级和3级肿瘤,推荐不进行重建的整块切除作为一种有价值的治疗选择.切除尺骨远端而不进行重建可获得出色的功能结果，与前臂旋转运动和手的功能保存。根据文献综述，这是最大的GCTUlna系列，我们建议对该主题进行多中心和比较研究。
