■通过分析脊柱影像学数据，探讨青少年特发性脊柱侧凸（AIS）患者矢状面对齐与冠状畸形之间的关系。
■纳入了4154例AIS患者，这些患者接受了脊柱的前后和外侧X线摄影，脊柱的Cobb角参数,宫颈前凸,C1-C2角度,T1斜率,胸椎后凸,腰椎前凸,骶骨斜坡,骨盆倾斜(PT),骨盆发病率（PI），颈椎矢状面垂直轴(SVA),和脊柱SVA进行分析。
■根据Cobb角的大小将患者分为两组：A组（Cobb角≤45°，n=414）和B组（Cobb角>45°，n=40)。在A组中,Cobb角与颈椎前凸角呈中等负相关(r=-0.637,P<0.001),C1-C2角呈弱正相关(|r|<0.3,P<0.05),T1斜率和胸椎后凸。B组,Cobb角与PT(r=0.398)、PI(r=0.360)呈轻度正相关(P<0.05)。两组男女颈椎前凸角度差异有统计学意义(P<0.05)。A组,颈椎前凸角与T1斜率呈显著正相关(P<0.01)(r=0.586),胸椎后凸(r=0.490),和矢状垂直轴(r=0.135)，与颈椎矢状位垂直轴（r=-0.128）和C1-C2角度（r=-0.155）呈显着负相关（P<0.01）。B组,颈椎前凸角与T1斜率呈显著正相关(P<0.05)(r=0.661),胸椎后凸(r=0.608)，腰椎前凸(r=0.425),骶骨斜率（r=0.434），矢状纵轴(r=0.335)。
■在Cobb角≤45º的AIS患者中，宫颈前凸与Cobb角呈显著负相关。AIS患者颈椎矢状形态受脊柱冠状畸形的影响,在AIS的治疗中起着重要作用。
UNASSIGNED: To investigate the relationship between sagittal alignment and coronal deformity in patients with adolescent idiopathic scoliosis (AIS) through analysis of the spinal imaging data.
UNASSIGNED: Four hundred and fifty-four AIS patients who underwent anteroposterior and lateral radiography of the while spine were enrolled, and the spinal parameters of Cobb angle, cervical lordosis, C1-C2 angle, T1 slope, thoracic kyphosis, lumbar lordosis, sacral slope, pelvic tilt (PT), pelvic incidence (PI), cervical sagittal vertical axis (SVA), and spinal SVA were analyzed.
UNASSIGNED: The patients were divided into two groups according to the size of the Cobb angle: group A (Cobb angle ≤45°, n=414) and group B (Cobb angle >45°, n=40). In group A, the Cobb angle was in a medium negative correlation with the cervical lordosis angle (r=-0.637, P<0.001), a weak positive correlation (|r|<0.3, P<0.05) with C1-C2 angle, T1 slope and thoracic kyphosis. In group B, the Cobb angle was in a mild positive correlation (P<0.05) with PT (r=0.398) and PI (r=0.360). The cervical lordosis angle was significantly (P<0.05) different between male and female patients in both groups. In Group A, the cervical lordosis angle was in a significantly (P<0.01) positive correlation with the T1 slope (r=0.586), thoracic kyphosis (r=0.490), and sagittal vertical axis (r=0.135), and a significantly (P<0.01) negative correlation with cervical sagittal vertical axis (r=-0.128) and C1-C2 angle (r=-0.155). In group B, the cervical lordosis angle was in a significantly (P<0.05) positive correlation with T1 slope (r=0.661), thoracic kyphosis (r=0.608), lumbar lordosis (r=0.425), sacral slope (r=0.434), and sagittal vertical axis (r=0.335).
UNASSIGNED: In AIS patients with the Cobb angle ≤45º, a significant negative correlation exists between the cervical lordosis and the Cobb angle. The sagittal morphology of the cervical spine in AIS patients is affected by the spinal coronal deformity, which plays an important role in the treatment of AIS.
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