Corneal sensitivity

角膜敏感度
  • 文章类型: English Abstract
    目的:评估黑人糖尿病患者的角膜敏感性,并确定与角膜敏感性变化相关的因素。
    方法:我们于2022年3月1日至7月31日在雅温得中心医院和Djoungolo区医院的国家肥胖中心进行了一项横断面比较病例对照研究。使用Cochet-Bonnet美学仪对所有18岁以上的糖尿病患者进行角膜敏感性测量,年龄和性别与临床健康对照人群相匹配。数据采用SPSS23.0版软件进行分析。小于5%的P值被认为是显著的。
    结果:共有111名糖尿病患者和111名非糖尿病患者参与了这项研究。糖尿病患者的平均年龄为53.46±12.74岁,非糖尿病患者为52.85±11.77岁(P=0.901)。糖尿病的平均病程为6.4±5.30年。糖尿病患者的角膜敏感性(44.56±9.59mm)低于非糖尿病患者(53.59±6.30mm),差异有统计学意义(P=0.000)。与糖尿病患者角膜敏感性降低相关的因素是糖尿病持续时间和血糖控制不良。
    结论:在糖尿病患者的眼科随访中,与糖尿病相关的角膜敏感性降低是一种需要系统筛查的并发症。
    OBJECTIVE: To evaluate the corneal sensitivity of black diabetic patients and identify factors associated with changes in corneal sensitivity.
    METHODS: We conducted a cross-sectional comparative case-control study at the National Obesity Center of the Yaounde Central Hospital and the Djoungolo District Hospital from March 1 to July 31, 2022. Corneal sensitivity was measured using the Cochet-Bonnet esthesiometer in all diabetic patients over 18 years of age, matched for age and sex to a clinically healthy control population. Data were analyzed using SPSS version 23.0 software. A P-value of less than 5% was considered significant.
    RESULTS: A total of 111 diabetic and 111 non-diabetic patients participated in the study. The mean age was 53.46±12.74 years for diabetics and 52.85±11.77 years for non-diabetics (P=0.901). The mean duration of diabetes was 6.4±5.30 years. Corneal sensitivity in diabetics was lower (44.56±9.59mm) compared to non-diabetics (53.59±6.30mm) with a statistically significant difference (P=0.000). Factors associated with decrease in corneal sensitivity in diabetics were duration of diabetes and poor glycemic control.
    CONCLUSIONS: Decrease in corneal sensitivity related to diabetes is a complication to be systematically screened for during the ophthalmologic follow-up of diabetic patients.
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  • 文章类型: Journal Article
    BACKGROUND: Traumatic dislocation of laser-assisted in situ keratomileusis (LASIK) corneal flaps is an uncommon postoperative complication that could occur any time after LASIK, and could be visually devastating. We evaluated the visual outcomes, corneal sensation, tear function, and dry eye questionnaire results of patients with traumatic dislocation of LASIK flaps, including one LASIK flap amputation.
    METHODS: This is a retrospective case series. Seven patients who were diagnosed with traumatic displacement of the LASIK flap and underwent flap replacement surgery between August 2014 and January 2019 were included.Patient\'s visual acuity, refraction, corneal sensitivity, non-invasive tear breakup time (NIBUT), tear meniscus height (TMH), and ocular surface disease index (OSDI) results were evaluated.
    RESULTS: The patients\' mean age was 35.86 ± 5.84 years, and 42.9 % (3/7) were male. The mean duration from LASIK to trauma was 8.86 ± 2.48 years.The mean preoperative and postoperative six-month corrected distance visual acuity (CDVA) were 0.55 ± 0.34 and 0.02 ± 0.03, respectively. The mean spherical equivalent and astigmatism at six months postoperatively was - 1.0 ± 0.95 D and - 0.5 ± 0.25 D, respectively. The corneal flap was clear and well-positioned at the final follow-up (mean: 28.57 ± 6.9 months). 85.71 % (6/7) of the patients showed worse corneal sensation in the injured eye. Interocular OSDI discrepancy was less in those whose last visit was more than 30 months after the trauma.
    CONCLUSIONS: Postoperative CDVAat six months was improved, and the refractive data also showed some improvement. The corneal nerve and tear function recovery peaked before 30 months, while the OSDI continued to show a strong trend of improvement beyond 30 months.
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