Abstract：
OBJECTIVE: To evaluate the corneal sensitivity of black diabetic patients and identify factors associated with changes in corneal sensitivity.
METHODS: We conducted a cross-sectional comparative case-control study at the National Obesity Center of the Yaounde Central Hospital and the Djoungolo District Hospital from March 1 to July 31, 2022. Corneal sensitivity was measured using the Cochet-Bonnet esthesiometer in all diabetic patients over 18 years of age, matched for age and sex to a clinically healthy control population. Data were analyzed using SPSS version 23.0 software. A P-value of less than 5% was considered significant.
RESULTS: A total of 111 diabetic and 111 non-diabetic patients participated in the study. The mean age was 53.46±12.74 years for diabetics and 52.85±11.77 years for non-diabetics (P=0.901). The mean duration of diabetes was 6.4±5.30 years. Corneal sensitivity in diabetics was lower (44.56±9.59mm) compared to non-diabetics (53.59±6.30mm) with a statistically significant difference (P=0.000). Factors associated with decrease in corneal sensitivity in diabetics were duration of diabetes and poor glycemic control.
CONCLUSIONS: Decrease in corneal sensitivity related to diabetes is a complication to be systematically screened for during the ophthalmologic follow-up of diabetic patients.
METHODS: We conducted a cross-sectional comparative case-control study at the National Obesity Center of the Yaounde Central Hospital and the Djoungolo District Hospital from March 1 to July 31, 2022. Corneal sensitivity was measured using the Cochet-Bonnet esthesiometer in all diabetic patients over 18 years of age, matched for age and sex to a clinically healthy control population. Data were analyzed using SPSS version 23.0 software. A P-value of less than 5% was considered significant.
RESULTS: A total of 111 diabetic and 111 non-diabetic patients participated in the study. The mean age was 53.46±12.74 years for diabetics and 52.85±11.77 years for non-diabetics (P=0.901). The mean duration of diabetes was 6.4±5.30 years. Corneal sensitivity in diabetics was lower (44.56±9.59mm) compared to non-diabetics (53.59±6.30mm) with a statistically significant difference (P=0.000). Factors associated with decrease in corneal sensitivity in diabetics were duration of diabetes and poor glycemic control.
CONCLUSIONS: Decrease in corneal sensitivity related to diabetes is a complication to be systematically screened for during the ophthalmologic follow-up of diabetic patients.
摘要：
目的：评估黑人糖尿病患者的角膜敏感性，并确定与角膜敏感性变化相关的因素。
方法：我们于2022年3月1日至7月31日在雅温得中心医院和Djoungolo区医院的国家肥胖中心进行了一项横断面比较病例对照研究。使用Cochet-Bonnet美学仪对所有18岁以上的糖尿病患者进行角膜敏感性测量，年龄和性别与临床健康对照人群相匹配。数据采用SPSS23.0版软件进行分析。小于5%的P值被认为是显著的。
结果：共有111名糖尿病患者和111名非糖尿病患者参与了这项研究。糖尿病患者的平均年龄为53.46±12.74岁，非糖尿病患者为52.85±11.77岁（P=0.901）。糖尿病的平均病程为6.4±5.30年。糖尿病患者的角膜敏感性（44.56±9.59mm）低于非糖尿病患者（53.59±6.30mm），差异有统计学意义（P=0.000）。与糖尿病患者角膜敏感性降低相关的因素是糖尿病持续时间和血糖控制不良。
结论：在糖尿病患者的眼科随访中，与糖尿病相关的角膜敏感性降低是一种需要系统筛查的并发症。
方法：我们于2022年3月1日至7月31日在雅温得中心医院和Djoungolo区医院的国家肥胖中心进行了一项横断面比较病例对照研究。使用Cochet-Bonnet美学仪对所有18岁以上的糖尿病患者进行角膜敏感性测量，年龄和性别与临床健康对照人群相匹配。数据采用SPSS23.0版软件进行分析。小于5%的P值被认为是显著的。
结果：共有111名糖尿病患者和111名非糖尿病患者参与了这项研究。糖尿病患者的平均年龄为53.46±12.74岁，非糖尿病患者为52.85±11.77岁（P=0.901）。糖尿病的平均病程为6.4±5.30年。糖尿病患者的角膜敏感性（44.56±9.59mm）低于非糖尿病患者（53.59±6.30mm），差异有统计学意义（P=0.000）。与糖尿病患者角膜敏感性降低相关的因素是糖尿病持续时间和血糖控制不良。
结论：在糖尿病患者的眼科随访中，与糖尿病相关的角膜敏感性降低是一种需要系统筛查的并发症。
