一些HIV(PWH)患者在没有开始抗逆转录病毒治疗(ART)的情况下多次检测呈阳性。我们在Soweto和Gugulethu的三家诊所进行了常规HIV检测后,对496个符合ART标准的PWH进行了调查,2014-2015年南非在该队列中的重复阳性测试者(RPT)中,我们比较了按既往治疗资格划分的治疗开始率,并在logistic回归模型中评估了治疗开始的心理社会预测因素.RPT在该队列中占PWH的33.8%。在先前的测试中报告有资格接受ART的人中,不到一半在重新测试后开始治疗,与2/3以前不符合治疗条件的RPT在得知符合治疗条件后即开始治疗形成对比.与不使用物质的人相比,那些报告通过物质使用应对的人更有可能拒绝治疗。反复测试的PWH代表处于非启动ART风险中的弱势群体,他们可能会从解决个性化应对策略的干预措施中受益。
Some people with HIV (PWH) test positive multiple times without initiating antiretroviral therapy (ART). We surveyed 496 ART-eligible PWH following routine HIV testing at three clinics in Soweto and Gugulethu, South Africa in 2014-2015. Among repeat positive testers (RPTs) in this cohort, we compared rates of treatment initiation by prior treatment eligibility and assessed psychosocial predictors of treatment initiation in logistic regression models. RPTs represented 33.8% of PWH in this cohort. Less than half of those who reported eligibility for ART on prior testing started treatment upon retesting, in contrast to two thirds of RPTs who were previously ineligible for treatment who started treatment once they learned of their eligibility. Those who reported
coping through substance use were more likely to decline treatment versus those not using substances. PWH who test repeatedly represent a vulnerable population at risk for ART non-initiation who may benefit from interventions addressing individualized
coping strategies.