Determining sources and spatial distributions of potentially toxic elements (PTEs) is a crucial issue of soil pollution survey. However, uncertainty estimation for source contributions remains lack, and accurate spatial prediction is still challenging. Robust Bayesian multivariate receptor model (RBMRM) was applied to the soil dataset of Qingzhou City (8 PTEs in 429 samples), to calculate source contributions with uncertainties. Multi-task convolutional neural network (MTCNN) was proposed to predict spatial distributions of soil PTEs. RBMRM afforded three sources, consistent with US-EPA positive matrix factorization. Natural source dominated As, Cr, Cu, and Ni contents (78.5 %∼86.1 %), and contributed 37.1 %, 61.0 %, and 65.9 % of Cd, Pb, and Zn, exhibiting low uncertainties with uncertainty index (UI) < 26.7 %. Industrial, traffic, and agricultural sources had significant influences on Cd, Pb, and Zn (30.2 %∼61.9 %), with UI < 39.3 %. Hg originated dominantly from atmosphere deposition (99.1 %), with relatively high uncertainties (UI=87.7 %). MTCNN acquired satisfactory accuracies, with R2 of 0.357-0.896 and nRMSE of 0.092-0.366. Spatial distributions of As, Cd, Cr, Cu, Ni, Pb, and Zn were influenced by parent materials. Cd, Hg, Pb, and Zn showed significant hotspot in urban area. This work conducted a new approach exploration, and practical implications for soil pollution regulation were proposed.

In this study, a novel approach is introduced, merging in silico prediction with a Convolutional Neural Network (CNN) framework for the targeted screening of in vivo metabolites in Liquid Chromatography-High Resolution Mass Spectrometry (LC-HRMS) fingerprints. Initially, three predictive tools, supplemented by literature, identify potential metabolites for target prototypes derived from Traditional Chinese Medicines (TCMs) or functional foods. Subsequently, a CNN is developed to minimize false positives from CWT-based peak detection. The Extracted Ion Chromatogram (EIC) peaks are then annotated using MS-FINDER across three levels of confidence. This methodology focuses on analyzing the metabolic fingerprints of rats administered with \"Pericarpium Citri Reticulatae - Fructus Aurantii\" (PCR-FA). Consequently, 384 peaks in positive mode and 282 in negative mode were identified as true peaks of probable metabolites. By contrasting these with \"blank serum\" data, EIC peaks of adequate intensity were chosen for MS/MS fragment analysis. Ultimately, 14 prototypes (including flavonoids and lactones) and 40 metabolites were precisely linked to their corresponding EIC peaks, thereby providing deeper insight into the pharmacological mechanism. This innovative strategy markedly enhances the chemical coverage in the targeted screening of LC-HRMS metabolic fingerprints.

BACKGROUND: Synthetic computed tomography (sCT) can be created from magnetic resonance imaging (MRI) utilizing newer software. sCT is yet to be explored as a possible alternative to routine CT (rCT). In this study, rCT scans and MRI-derived sCT scans were obtained on a cadaver. Morphometric analysis was performed comparing the 2 scans. The ExcelsiusGPS robot was used to place lumbosacral screws with both rCT and sCT images.
METHODS: In total, 14 screws were placed. All screws were grade A on the Gertzbein-Robbins scale. The mean surface distance difference between rCT and sCT on a reconstructed software model was -0.02 ± 0.05 mm, the mean absolute surface distance was 0.24 ± 0.05 mm, and the mean absolute error of radiodensity was 92.88 ± 10.53 HU. The overall mean tip distance for the sCT versus rCT was 1.74 ± 1.1 versus 2.36 ± 1.6 mm (p = 0.24); mean tail distance for the sCT versus rCT was 1.93 ± 0.88 versus 2.81 ± 1.03 mm (p = 0.07); and mean angular deviation for the sCT versus rCT was 3.2° ± 2.05° versus 4.04°± 2.71° (p = 0.53).
CONCLUSIONS: MRI-based sCT yielded results comparable to those of rCT in both morphometric analysis and robot-assisted lumbosacral screw placement in a cadaver study.

UNASSIGNED: This study examines the performance of active learning-aided systematic reviews using a deep learning-based model compared to traditional machine learning approaches, and explores the potential benefits of model-switching strategies.
UNASSIGNED: Comprising four parts, the study: 1) analyzes the performance and stability of active learning-aided systematic review; 2) implements a convolutional neural network classifier; 3) compares classifier and feature extractor performance; and 4) investigates the impact of model-switching strategies on review performance.
UNASSIGNED: Lighter models perform well in early simulation stages, while other models show increased performance in later stages. Model-switching strategies generally improve performance compared to using the default classification model alone.
UNASSIGNED: The study\'s findings support the use of model-switching strategies in active learning-based systematic review workflows. It is advised to begin the review with a light model, such as Naïve Bayes or logistic regression, and switch to a heavier classification model based on a heuristic rule when needed.

In the digital transformation of Chinese pharmaceutical industry, how to efficiently govern and analyze industrial data and excavate the valuable information contained therein to guide the production of drug products has always been a research hotspot and application difficulty. Generally, the Chinese pharmaceutical technique is relatively extensive, and the consistency of drug quality needs to be improved. To address this problem, we proposed an optimization method combining advanced calculation tools(e.g., Bayesian network, convolutional neural network, and Pareto multi-objective optimization algorithm) with lean six sigma tools(e.g., Shewhart control chart and process performance index) to dig deeply into historical industrial data and guide the continuous improvement of pharmaceutical processes. Further, we employed this strategy to optimize the manufacturing process of sporoderm-removal Ganoderma lucidum spore powder. After optimization, we preliminarily obtained the possible interval combination of critical parameters to ensure the P_(pk) values of the critical quality properties including moisture, fineness, crude polysaccharide, and total triterpenes of the sporoderm-removal G. lucidum spore powder to be no less than 1.33. The results indicate that the proposed strategy has an industrial application value.

The development of ecological restoration projects is unsatisfactory, and soil erosion is still a problem in ecologically restored areas. Traditional soil erosion studies are mostly based on satellite remote sensing data and traditional soil erosion models, which cannot accurately characterize the soil erosion conditions in ecological restoration areas (mainly plantation forests). This paper uses high-resolution unmanned aerial vehicle (UAV) images as the base data, which could improve the accuracy of the study. Considering that traditional soil erosion models cannot accurately express the complex relationships between erosion factors, this paper applies convolutional neural network (CNN) models to identify the soil erosion intensity in ecological restoration areas, which can solve the problem of nonlinear mapping of soil erosion. In this study area, compared with the traditional method, the accuracy of soil erosion identification by applying the CNN model improved by 25.57%, which is better than baseline methods. In addition, based on research results, this paper analyses the relationship between land use type, vegetation cover, and slope and soil erosion. This study makes five recommendations for the prevention and control of soil erosion in the ecological restoration area, which provides a scientific basis and decision reference for subsequent ecological restoration decisions.

The formation of urban districts and the appeal of densely populated areas reflect a spatial equilibrium in which workers migrate to locations with greater urban vitality but diminished environmental qualities. However, the pandemic and associated health concerns have accelerated remote and hybrid work modes, altered people\'s sense of place and appreciation of urban density, and transformed perceptions of desirable places to live and work. This study presents a systematic method for evaluating the trade-offs between perceived urban environmental qualities and urban amenities by analysing post-pandemic urban residence preferences. By evaluating neighbourhood Street View Imagery (SVI) and urban amenity data, such as park sizes, the study collects subjective opinions from surveys on two working conditions (work-from-office or from-home). On this basis, several Machine Learning (ML) models were trained to predict the preference scores for both work modes. In light of the complexity of work-from-home preferences, the results demonstrate that the method predicts work-from-office scores with greater precision. In the post-pandemic era, the research aims to shed light on the development of a valuable instrument for driving and evaluating urban design strategies based on the potential self-organisation of work-life patterns and social profiles in designated neighbourhoods.

Coronavirus Disease-2019 (COVID-19) causes Severe Acute Respiratory Syndrome-Corona Virus-2 (SARS-CoV-2) and has opened several challenges for research concerning diagnosis and treatment. Chest X-rays and computed tomography (CT) scans are effective and fast alternatives to detect and assess the damage that COVID causes to the lungs at different stages of the disease. Although the CT scan is an accurate exam, the chest X-ray is still helpful due to the cheaper, faster, lower radiation exposure, and is available in low-incoming countries. Computer-aided diagnostic systems based on Artificial Intelligence (AI) and computer vision are an alternative to extract features from X-ray images, providing an accurate COVID-19 diagnosis. However, specialized and expensive computational resources come across as challenging. Also, it needs to be better understood how low-cost devices and smartphones can hold AI models to predict diseases timely. Even using deep learning to support image-based medical diagnosis, challenges still need to be addressed once the known techniques use centralized intelligence on high-performance servers, making it difficult to embed these models in low-cost devices. This paper sheds light on these questions by proposing the Artificial Intelligence as a Service Architecture (AIaaS), a hybrid AI support operation, both centralized and distributed, with the purpose of enabling the embedding of already-trained models on low-cost devices or smartphones. We demonstrated the suitability of our architecture through a case study of COVID-19 diagnosis using a low-cost device. Among the main findings of this paper, we point out the performance evaluation of low-cost devices to handle COVID-19 predicting tasks timely and accurately and the quantitative performance evaluation of CNN models embodiment on low-cost devices.

In the present contribution, a novel approach based on multivariate curve resolution and deep learning (DL) is proposed for quantitative mass spectrometry imaging (MSI) as a potent technique for identifying different compounds and creating their distribution maps in biological tissues without need for sample preparation. As a case study, chlordecone as a carcinogenic pesticide was quantitatively determined in mouse liver using matrix-assisted laser desorption ionization-MSI (MALDI-MSI). For this purpose, data from seven standard spots containing 0 to 20 picomoles of chlordecone and four unknown tissues from the mouse livers infected with chlordecone for 1, 5, and 10 days were analyzed using a convolutional neural network (CNN). To solve the lack of sufficient data for CNN model training, each pixel was considered as a sample, the designed CNN models were trained by pixels in training sets, and their corresponding amounts of chlordecone were obtained by multivariate curve resolution-alternating least-squares (MCR-ALS). The trained models were then externally evaluated using calibration pixels in test sets for 1, 5, and 10 days of exposure, respectively. Prediction R2 for all three data sets ranged from 0.93 to 0.96, which was superior to support vector machine (SVM) and partial least-squares (PLS). The trained CNN models were finally used to predict the amount of chlordecone in mouse liver tissues, and their results were compared with MALDI-MSI and GC-MS methods, which were comparable. Inspection of the results confirmed the validity of the proposed method.

Prediction of the energy, active production from the PV solar plant is a challenge in cloudy weather or with clouds over the solar plant; therefore, it has impact in the planning of the power system, especially in the season analysis and prediction accuracy adjustments, for example in holidays. In 2022, some authors published some analysis associated to horizontal pyranometers and the limits in the evaluation of the data, the Mean Bias Error of Daily Solar Irradiation average (MIEave) ranges from 0.17% to 2.86% associated a sudden change in the weather, it increases the \"risk of misestimating the potential electricity generation\" with short-term error of more than 50% and the Global Horizontal Irradiance (GHI) has a mean bias error (MBE) of at least ±8% [1]. In this research article, a novel proposal for short-term forecasting combines the satellite with meteorological station data and statistical model associated to the new seasonality analysis by using two approaches: i) NeuralProphet, Ridge regression, ii) Long Short-Term Memory with convolutional neural networks. Besides, it requires three KPI as feedback, it is the mean absolute error (MAE), relative Root mean square error (RMSE), and mean absolute percentage error (MAPE). The results demonstrate a MAPE of 5.93% and a computational time 852.10 s and the comparison with new predictions methods from 2019 to 2021. This research article illustrates the new approach with the forecasting method in a case of the PV solar plant in Peru and proves the robustness and seasonality results, and new short-terms improvements associated to external influence as cloudy conditions and resource availability. Our findings are an improvement of the model MAPE 12.14%-5.93%; even compared with the literature and currently models as ARIMA-LSTM with 10.57%, LSTM with NN and G, SARIMA and SVM considering Gaussian White Noise with 8.14% and Prophet with SVM with 8.81%.