身心干预(MBIs)包括基于正念的干预(MiBIs),基于冥想和口头禅的干预措施(MMI),和基于运动的干预(MoBI)。这些方法已证明在改善创伤后应激障碍(PTSD)症状方面具有初步功效。然而,以前的系统评价和荟萃分析已经指出,这一研究领域受到比较条件不足的限制,测量的异质性,缺乏客观的结果衡量标准。由于这些原因,有必要对现有的最高质量证据进行更新审查.我们使用医疗保健研究和质量机构(AHRQ)资助的PTSD-Repository证据表来识别相关研究并评估偏倚风险如下:搜索于2018年6月至2022年6月进行,数据库包括PTSDpubs(以前称为PILOTS),Ovid®MEDLINE®,科克伦中部,Embase®,护理和相关健康文献累积指数(CINAHL®),Scopus,和PsycINFO®。26项随机对照试验符合我们的纳入标准。在确定研究并从PTSD-Repository证据表中检索偏见信息的风险之后,我们提取了额外的数据并综合了证据。MIBIs和MMI的证据强度被评为较低,主要是由于矛盾的结果,有源和无源比较器的使用不一致,和高风险的偏见。MoBI的证据强度被评为中等,因为个别研究始终支持干预措施,并且有相对大量的研究和参与者。在26项纳入的研究中,只有两项包括客观结果衡量标准。讨论了未来MBI研究和治疗PTSD的临床应用的意义。
Mind-body interventions (MBIs) include mindfulness-based interventions (MiBIs), meditation- and mantra-based interventions (MMIs), and movement-based interventions (MoBIs). These approaches have demonstrated preliminary efficacy in improving posttraumatic stress disorder (PTSD) symptoms. However, previous systematic reviews and meta-analyses have noted that this area of research is limited by inadequate comparator conditions, heterogeneity of measurement, and absence of objective outcome measures. For these reasons, an updated
review of the highest-quality evidence available is warranted. We used the Agency for Healthcare Research and Quality (AHRQ)-funded evidence tables for the PTSD-Repository to identify relevant studies and assess the risk of bias as follows: The search was conducted between June 2018 and June 2022, and databases included PTSDpubs (formerly PILOTS), Ovid® MEDLINE®, Cochrane CENTRAL, Embase®, the Cumulative Index to Nursing and Allied Health Literature (CINAHL®), SCOPUS, and PsycINFO®. Twenty-six randomized controlled trials met our inclusion criteria. After identifying studies and retrieving risk of bias information from the PTSD-Repository evidence tables, we extracted additional data and synthesized the evidence. The strength of evidence was rated as low for MiBIs and MMIs, largely due to contradicting results, inconsistent use of active versus passive comparators, and high risk of bias. The strength of evidence for MoBIs was rated as moderate due to individual studies consistently favoring the intervention and a relatively large number of studies and participants. Of the 26 included studies, only two included objective outcome measures. Implications for future MBI research and clinical applications for treating PTSD are discussed.