墨西哥正在迅速老龄化,这使得确定影响认知的生命过程因素成为公共卫生的优先事项。我们评估了墨西哥儿童的数量与认知的关系,一个快速老龄化的国家,在最近的老年人群中经历了生育率下降。
我们分析老年人(50岁以上,n=11,380)来自2015年墨西哥健康与老龄化研究。受访者按出生儿童数量(0-1、2-3、4-5、6+)进行分类。使用普通最小二乘回归,我们估计生育史和认知之间的独立关联,社会经济,健康,和社会心理因素。
我们观察到儿童数量(在2-3个儿童达到峰值)与认知功能之间呈倒U形关系,不分性别。在针对混杂变量进行调整的回归分析中,只有女性有0-1名(与2-3名儿童相比)与认知功能较差有关。不管性别,有6+(vs2-3名儿童)与认知功能较差相关。即使考虑到社会经济因素,这些协会仍然很重要。健康,employment,和社会心理因素。
我们的结果表明,生育史可能在晚年认知健康中起作用,并提供证据表明,低生育率和高生育率可能与认知功能较差有关。我们讨论性别差异。
Mexico is aging rapidly, which makes identification of life-course factors influencing cognition a public health priority. We evaluate how the number of children one has relates to cognition in Mexico, a rapidly aging country that experienced fertility declines across recent cohorts of older people.
We analyze older adults (age 50+, n = 11,380) from the 2015 Mexican Health and Aging Study. Respondents were categorized by number of children ever born (0-1, 2-3, 4-5, 6+). Using ordinary least squares regression, we estimate independent associations between fertility history and cognition accounting for demographic, socioeconomic, health, and psychosocial factors.
We observed an inverse U-shaped relationship between number of children (peaking at 2-3 children) and cognitive function, regardless of gender. In regression analyses adjusted for confounding variables, having 0-1 (vs 2-3 children) was associated with poorer cognitive function only for females. Regardless of gender, having 6+ (vs 2-3 children) was associated with poorer cognitive function. These associations remained significant even after accounting for socioeconomic, health, employment, and psychosocial factors.
Our results suggest fertility history may play a role in late-life cognitive health and provide evidence that both low and high fertility may relate to poorer cognitive function. We discuss differences by gender.