UNASSIGNED:很少有病例报告显示药物涂层球囊(DCB)作为颈动脉支架内再狭窄(CAISR)的新兴治疗方法有希望的结果。在这里,我们报告了6例CAISR,这些CAISR采用DCB治疗,有或没有新的支架展开。
UNASSIGNED:颈动脉支架内再狭窄是一种高危疾病,估计发病率在6%至40%之间差异很大。现在有几种策略可用于CAISR的管理,包括常规的球囊血管成形术,斑块改良球囊血管成形术,和新的支架放置。
UNASSIGNED:对2011年至2021年在贝勒斯科特和怀特普莱诺心脏医院诊断为严重CAISR的连续患者进行了回顾性研究。这项研究得到了贝勒斯科特和怀特研究所机构审查委员会的批准。
UNASSIGNED:6名患者接受了DCB血管成形术,在栓塞保护装置下放置或不放置支架。CAISR的分辨率在所有病例中都实现了0%至10%的残余狭窄。按照程序,1例患者出现短暂的晕厥发作,并伴有球囊充气,球囊放气后立即恢复。出院前没有明显的神经或心脏事件。所有患者在随访时无症状,术后12、24和36个月无神经或心脏事件报告。
未经批准:虽然CAISR治疗仍然是一个具有挑战性的条件,我们的研究表明,与其他常规治疗方案相比,使用有或没有支架置入的DCB是一种可行且有前景的治疗方案.
结论:颈动脉支架内再狭窄治疗仍然是一个具有挑战性的条件。我们的研究表明,与当前的常规治疗方案相比,使用有或没有支架放置的药物涂层球囊是可行且有前途的治疗方案。
Few
case reports have demonstrated promising results of drug-coated balloons (DCBs) as an emerging management for carotid artery in-stent restenosis (CAISR). Herein, we report 6 cases of CAISR which were treated with a DCB with or without new stent deployment.
Carotid artery in-stent restenosis is a high-risk condition with an estimated incidence rate that varies widely from 6% to 40%. Several strategies are available now for the management of the CAISR including conventional balloon angioplasty, plaque modification balloon angioplasty, and new stent placement.
A retrospective review of consecutive patients with a diagnosis of severe CAISR at Baylor Scott & White The Heart Hospital Plano from 2011 to 2021 was performed. This study was approved by the Baylor Scott & White Research Institute institutional review board.
Six patients underwent DCB angioplasty with or without stent placement under an embolic protection device. Resolution of CAISR was achieved in all cases with 0% to 10% residual stenosis in all cases. Following the procedure, 1 patient had a brief episode of syncope with balloon inflation with immediate recovery on deflation of the balloon. There were otherwise no significant neurological or cardiac events prior to discharge. All patients were asymptomatic at their follow-up visit with no neurological or cardiac events reported at 12, 24, and 36 months following the procedure.
While CAISR treatment remains a challenging condition, our study shows that the use of DCB with or without stent placement is a feasible and promising treatment option when compared with other conventional treatment options.
Carotid artery in-stent restenosis treatment remains a challenging condition. Our study shows that the use of drug coated balloon with or without stent placement is a feasible and promising treatment option when compared with current conventional treatment options.