Carotid Artery Injuries

颈动脉损伤
  • 文章类型: Case Reports
    背景:颅外颈内动脉(ICA)创伤性假性动脉瘤(PSA)的最佳支架置入方法仍未得到充分研究。我们介绍了一例颅外ICA的创伤性假性动脉瘤,并通过支架置入治疗,并回顾了先前发表的类似病例。
    方法:系统评价遵循PRISMA-S指南,包括研究通过支架置入治疗颅外ICA的创伤性假性动脉瘤的研究。统计分析评估了损伤类型和支架类型之间的关联,双重抗血小板治疗(DAPT)持续时间,和临床表现,以及支架类型和DAPT持续时间之间的关联。
    结果:我们的搜索得出了82篇出版物,其中135例颅外ICAPSA患者接受支架置入治疗。穿透性而非钝性损伤患者出现颈部血肿的几率是其12.2倍(P=0.000002)。与裸金属支架相比,覆盖支架使用穿透性而不是钝性损伤的几率要高2.02倍。(P=0.0029)。与覆盖相比,裸金属支架的DAPT持续时间较短,DAPT持续时间少于一个月的几率高1.25(P=0.001)。
    结论:在外伤性颅外ICA假性动脉瘤中,与钝器损伤相比,覆膜支架更常用于穿透性损伤。与钝性损伤相比,穿透性损伤与血肿的表现更密切相关。支架类型可能会影响推荐的DAPT持续时间。外科医生在选择外伤性颅外ICA假性动脉瘤患者的支架类型和DAPT持续时间时应考虑这些发现。
    The optimal stenting approach for traumatic pseudoaneurysms (PSA) of the extracranial internal carotid artery (ICA) remains underinvestigated. We present a case of a traumatic pseudoaneurysm of the extracranial ICA managed with stenting and review of prior published similar cases.
    The systematic review followed PRISMA-S guidelines and included studies that investigated traumatic pseudoaneurysms of the extracranial ICA managed by stent placement. Statistical analysis assessed the association between the type of injury and stent type, dual antiplatelet therapy (DAPT) duration, and clinical presentation, and the association between stent type and DAPT duration.
    Our search yielded 82 publications with 135 patients with extracranial ICA PSA treated with stenting. The odds of neck hematoma presentation was 12.2 times greater for patients with penetrating rather than blunt injuries (P = 0.000002). Covered stents had 2.02 times higher odds of use for penetrating rather than blunt injuries compared to bare metal stents. (P = 0.0029). Shorter duration DAPT was seen with bare metal stents having 1.25 higher odds of DAPT duration less than one month compared to covered (P = 0.001).
    In traumatic extracranial ICA pseudoaneurysms, covered stents are used more commonly for penetrating injuries compared to blunt injuries. Penetrating injuries are more strongly associated with the presentation of a hematoma compared to blunt injuries. Stent type may influence the recommended DAPT duration. Surgeons should consider these findings when selecting stent type and DAPT duration with patients presenting with traumatic extracranial ICA pseudoaneurysm.
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  • 文章类型: Meta-Analysis
    目的:钝性脑血管损伤(BCVI)包括外伤后的颈动脉和/或椎动脉损伤,并传达中风风险增加。我们进行了系统评价和荟萃分析,以全面总结与BCVI后卒中风险相关的预后因素。
    方法:我们检索了1946年1月至2023年6月的EMBASE和MEDLINE数据库。我们确定了报告患者或损伤因素与BCVI后卒中风险之间关联的研究。我们使用随机效应方法对比值比(OR)进行荟萃分析,并使用QUIPS工具评估个体研究偏倚风险。我们分别汇总了调整后和未调整后的分析,以更高的确定性突出估计。
    结果:我们纳入了26项队列研究,涉及20,458例钝性外伤患者.BCVI后卒中的总发生率为7.7%。研究主要是来自北美的回顾性队列,包括颈动脉和椎动脉损伤。BCVI的诊断最常见于CT血管造影。我们以中至高的确定性证明,与卒中风险增加相关的因素包括颈动脉损伤(与椎动脉损伤相比,未调整的赔率比[UOR]1.94,95%CI1.62至2.32),III级伤害(与I级或II级相比)(uOR2.45,95%CI1.88至3.20),IV级伤害(UOR3.09,95%CI2.20至4.35),多动脉损伤(UOR3.11(95%CI2.05至4.72),入院时低血压的发生(校正比值比[aOR]1.32,95%CI0.87~2.03)和更高的全身损伤严重程度(aOR5.91,95%CI1.90~18.39).
    结论:局部解剖损伤模式,总体损伤负担和血流动力学导致BCVI相关卒中风险.这些发现为风险分层提供了基础证据,以支持临床决策和进一步研究。
    OBJECTIVE: Blunt cerebrovascular injury (BCVI) includes carotid and/or vertebral artery injury following trauma, and conveys an increased stroke risk. We conducted a systematic review and meta-analysis to provide a comprehensive summary of prognostic factors associated with risk of stroke following BCVI.
    METHODS: We searched the EMBASE and MEDLINE databases from January 1946 to June 2023. We identified studies reporting associations between patient or injury factors and risk of stroke following BCVI. We performed meta-analyses of odds ratios (ORs) using the random effects method and assessed individual study risk of bias using the QUIPS tool. We separately pooled adjusted and unadjusted analyses, highlighting the estimate with the higher certainty.
    RESULTS: We included 26 cohort studies, involving 20,458 patients with blunt trauma. The overall incidence of stroke following BCVI was 7.7 %. Studies were predominantly retrospective cohorts from North America and included both carotid and vertebral artery injuries. Diagnosis of BCVI was most commonly confirmed with CT angiography. We demonstrated with moderate to high certainty that factors associated with increased risk of stroke included carotid artery injury (as compared to vertebral artery injury, unadjusted odds ratio [uOR] 1.94, 95 % CI 1.62 to 2.32), Grade III Injury (as compared to grade I or II) (uOR 2.45, 95 % CI 1.88 to 3.20), Grade IV injury (uOR 3.09, 95 % CI 2.20 to 4.35), polyarterial injury (uOR 3.11 (95 % CI 2.05 to 4.72), occurrence of hypotension at the time of hospital admission (adjusted odds ratio [aOR] 1.32, 95 % CI 0.87 to 2.03) and higher total body injury severity (aOR 5.91, 95 % CI 1.90 to 18.39).
    CONCLUSIONS: Local anatomical injury pattern, overall burden of injury and flow dynamics contribute to BCVI-related stroke risk. These findings provide the foundational evidence base for risk stratification to support clinical decision making and further research.
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  • 文章类型: Journal Article
    在非穿透性后出现颈部疼痛的年轻成年人,颈部看似微不足道的创伤,有颈动脉夹层和随后中风的风险。运动相关的颈部损伤是主要原因。体格检查通常不明显,尽管可能不愿意让年轻患者接受辐射,放射学成像是诊断动脉壁破裂的核心。对颈部动脉夹层进行了全面的文献检索,证据被仔细检查了。我们讨论了损伤的典型机制,症状,解剖学考虑和临床辅助诊断颈动脉夹层。虽然发病率低,颈动脉夹层的死亡率为7%.因此,对一线医生来说,对诊断有高度怀疑和组织放射检查的门槛很低是很重要的,特别是计算机断层扫描。早期发现颈部动脉夹层将触发临床协议,要求多学科团队管理这种情况。总的来说,涉及内膜瓣的颈动脉夹层的治疗基于指南的建议是通过抗血小板治疗,而导致假性动脉瘤或血栓形成的颈动脉夹层的治疗则通过手术干预或血管内技术进行.对这些患者建议密切随访结合抗血栓治疗,目标是预防中风。
    Young adults who present to the ED with neck pain following non-penetrating, seemingly trivial trauma to the neck, are at risk of neck artery dissection and subsequent stroke. Sport-related neck injury is the chief cause. Physical examination may often be unremarkable, and although there may be reluctance to expose young patients to radiation, radiological imaging is central to making a diagnosis of arterial wall disruption. A comprehensive literature search was performed in relation to neck artery dissection, and the evidence was scrutinised. We discuss the typical mechanism of injury, symptoms, anatomical considerations and clinical aids in diagnosis of neck artery dissection. Although the incidence is low, neck artery dissection has a mortality of 7%. As such, it is important for front-line physicians to have a high suspicion of the diagnosis and a low threshold to organise radiological examinations, specifically computerised tomography. Early detection of neck artery dissection will trigger clinical protocols that call for multi-disciplinary team management of this condition. In general, guideline-based recommendation for the management of neck artery dissection involving an intimal flap is by anti-platelet therapy while treatment of neck artery dissection that results in a pseudo-aneurysm or thrombosis is managed by surgical intervention or endovascular techniques. Close follow up combined with antithrombotic treatment is recommended in these individuals, the goal being prevention of stroke.
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  • 文章类型: Review
    颈动脉内膜切除术(CEA)后的假性动脉瘤(PA)是一种罕见且危险的并发症。近年来,血管内方法已成为首选开放手术,因为它具有较小的侵入性,并减少了已经手术的颈部的并发症。尤其是脑神经损伤.我们报告了一例CEA后导致吞咽困难的大型PA病例,通过部署两个球囊扩张覆膜支架和颈外动脉线圈栓塞术成功治疗。还报道了自2000年以来通过血管内手段治疗的所有CEA后PAs病例的文献综述。这项研究是在Pubmed数据库上进行的,使用关键词“颈动脉内膜切除术后的颈动脉假性动脉瘤,颈动脉内膜切除术后的假性动脉瘤,颈动脉内膜切除术后假性动脉瘤,“和”颈动脉假性动脉瘤。\"
    Pseudoaneurysm (PA) following carotid endarterectomy (CEA) is a rare and dangerous complication. In recent years endovascular approach has been preferred to open surgery as it is less invasive and reduces complications in an already operated neck, especially cranial nerve injuries. We report a case of large post-CEA PA causing dysphagia, successfully treated by deployment of two balloon-expandable covered stents and coil embolization of the external carotid artery. A literature review dealing with all cases of post-CEA PAs since 2000 treated by endovascular means is also reported. The research was conducted on Pubmed database using keywords \"carotid pseudoaneurysm after carotid endarterectomy,\" \"false aneurysm after carotid endarterectomy,\" \"postcarotid endarterectomy pseudoaneurysm,\" and \"carotid pseudoaneurysm.\"
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  • 文章类型: Review
    意外颈动脉损伤是一种罕见但严重的中心静脉导管插入并发症。止血可能不容易通过手动压缩来实现;因此,手术或血管内治疗仍然是意外颈动脉损伤的主要手段.然而,并非所有患者都适合手术。血管闭合装置广泛用于股动脉中以实现止血和早期下床活动。偶尔有报道在其他血管床中使用血管闭合装置。在这里,我们介绍一例医源性左颈总动脉损伤的血管闭合装置治疗,这有助于未来对这种并发症的管理。
    Accidental carotid artery injury is an uncommon but serious central venous catheter insertion complication. Hemostasis might not be readily achieved by manual compression; therefore, surgery or endovascular treatment remains the mainstay for accidental carotid artery injury. However, not all patients are suitable candidates for surgery.Vascular closure devices are widely used in femoral arteries to achieve hemostasis and early ambulation. The use of vascular closure devices is occasionally reported in other vascular beds. Here we present a case of an iatrogenic left common carotid artery injury treated by vascular closure device, which is of help in the future management of this complication.
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  • 文章类型: Review
    背景:血管异常,包括夹层和动脉瘤,在常染色体显性肾病(ADPKD)患者中可以发现。虽然已经报道了10%-25%的ADPCKD的颅内动脉瘤,在其他地方发生的情况极为罕见。
    方法:这是一例首例ADPCKD患者,表现为左颈外动脉假性动脉瘤破裂。
    结论:颈动脉动脉瘤的破裂是罕见的,具有潜在的高发病率。血管内和手术方法是成功治疗的有效策略,取决于病因。location,和外科医生的经验。
    BACKGROUND: Vascular abnormalities, including dissections and aneurysms, can be found in patients with autosomal dominant kidney disease (ADPKD). While intracranial aneurysms have been reported in 10%-25% of ADPCKD, occurrences at other locations are exceedingly rare.
    METHODS: This is a first case report of a patient with ADPCKD who presented with a rupture of the left external carotid artery pseudoaneurysm.
    CONCLUSIONS: Rupture of a carotid artery aneurysm is rare with potentially high morbidity. An endovascular and surgical approach are effective strategies for successful management that depends on etiology, location, and surgeon experience.
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  • 文章类型: Journal Article
    目的:小儿口咽部创伤很常见。尽管大多数案件都能顺利解决,有报道称颈内动脉损伤会导致毁灭性的神经血管后遗症。对于看似轻微口咽外伤的儿童,CT血管造影(CTA)的实用性存在重大争议。这项研究的目的是根据CTA结果评估诊断和治疗的变化。
    方法:对PubMed的全面搜索,Embase,CINAHL,Scopus,Cochrane耳朵,鼻子和喉咙疾病小组试验登记册,ClinicalTrials.gov数据库按照PRISMA指南进行。
    结果:搜索产生了5,078个独特的摘要,其中包括8篇文章。共纳入662例患者,293有任何CT头颈部成像,和255与CTA。在CTA上发现了11个颈动脉损伤/异常,包括颈动脉周围的水肿(n=8),潜在的内膜撕裂(n=1),颈动脉痉挛(n=1),颈动脉压迫(n=1)。可能导致临床管理变化的CTA影像学表现的合并比例为0.00(95%CI0.00-0.43)。对10例患者进行了血管造影,6例因CTA异常。血管造影确定了1例血管痉挛患者和2例颈动脉内膜破裂无血栓患者。无患者行血管修复或脑血管损伤。
    结论:CTA成像在少数情况下产生放射学异常。这些结果不支持常规使用CTA筛查小儿口咽外伤时,平衡辐射的风险,因为它很少导致管理变更,并且没有显示改善结果。
    方法:N/A喉镜,133:457-466,2023年。
    Pediatric oropharyngeal trauma is common. Although most cases resolve uneventfully, there have been reports of internal carotid artery injury leading to devastating neurovascular sequelae. There is significant controversy regarding the utility of CT angiography (CTA) in children with seemingly minor oropharyngeal trauma. The goal of this study was to appraise changes in diagnosis and treatment based on CTA results.
    A comprehensive search of PubMed, Embase, CINAHL, Scopus, the Cochrane Ear, Nose and Throat Disorders Group Trials Register, and the ClinicalTrials.gov database was performed following PRISMA guidelines.
    The search yielded 5,078 unique abstracts, of which 8 articles were included. A total of 662 patients were included, with 293 having any CT head/neck imaging, and 255 with CTA. Eleven injuries/abnormalities of the carotid were found on CTAs, comprising edema around the carotid (n = 8), potential intimal tear (n = 1), carotid spasm (n = 1), and carotid compression (n = 1). The pooled proportion of imaging findings on CTA that could lead to changes in clinical management was 0.00 (95% CI 0.00-0.43). Angiography was obtained in 10 patients, in 6 cases due to abnormal CTA. Angiography identified 1 patient with vessel spasm and two patients with carotid intima disruption without thrombus. No patient underwent vascular repair or suffered cerebrovascular injury.
    Imaging with CTA yielded radiological abnormalities in a few instances. These results do not support the routine use of CTA in screening pediatric oropharyngeal trauma when balanced against the risk of radiation, as it rarely resulted in management changes and was not shown to improve outcomes.
    N/A Laryngoscope, 133:457-466, 2023.
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  • 文章类型: Journal Article
    <b>简介:</b>颈动脉损伤构成一组罕见的损伤。这项研究提供了超过20年的44例医源性颈动脉损伤患者的治疗结果。患者由血管科的医生团队治疗,1997-2017年在弗罗茨瓦夫进行的普通和移植手术(系主任,教授KlemensSkóra,MD,和教授。PiotrSzyber,MD,博士-经许可使用的材料)。</br></br><b>目的:</b>分析的目的是:估计不同形式的医源性颈总动脉和颈内动脉损伤的频率,为了评估治疗结果,根据损伤类型评估最有效的手术方法,并制定有效的术前计划,术中和术后方案。</br></br><b>讨论和结果:</b>各种颈动脉损伤的频率(钝性,急性,交通)在几年之间是恒定的,但是医源性伤害的数量肯定会随着时间的推移而增加。颈动脉损伤患者的预后,特别是当合并多器官创伤时,是最严重的。急性和医源性损伤均获得了显着更好的治疗效果。这主要是由于更容易和更快的诊断和更好的条件帮助病人。</br></br><b>结论:精心设计的手术方案,即主要是UTH的管理,并由第一运营团队进行临时排水,降低神经系统并发症的风险。
    <b>Introduction:</b> Injuries of the carotid artery constitute a rare group of injuries. This study presents results of the treatment of 44 patients with iatrogenic carotid artery injuries for over 20 years. The patients were treated by the team of doctors of the Department of Vascular, General and Transplant Surgery in Wroclaw in the years 1997-2017 (Head of the Department Prof. Klemens Skóra, MD, and Prof. Piotr Szyber, MD, PhD - material used with permission). </br></br> <b>Aim:</b> Aims of the analysis are: to estimate the frequency of different forms of iatrogenic injuries to the common and internal carotid artery, to evaluate the results of treatment, to assess the most effective surgical method depending on the type of injury, and develop an effective preoperative, intraoperative and postoperative regimen.</br></br> <b>Discussion and results:</b> The frequency of various carotid artery injuries (blunt, acute, traffic) was constant between years, but the number of iatrogenic injuries definitely increased over time. The prognosis for patients with carotid artery injury, especially when combined with multi-organ trauma, is the gravest. Significantly better treatment results were achieved with both acute and iatrogenic injuries. This is mainly due to easier and quicker diagnosis and better conditions for assisting patients.</br></br> <b>Conclusions:</b> In iatrogenic injuries, a well-designed surgical scheme, i.e. primarily the administration of UTH and placing a temporary flow drain by the first operating team, reduces the risk of neurological complications.
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  • 文章类型: Meta-Analysis
    目的:分析计算机断层扫描血管造影(CTA)在识别颈内动脉(ICA)损伤和降低口咽部创伤(OT)后神经系统检查正常的儿童脑血管意外(CVA)发生率中的应用。
    方法:PubMed,Scopus,CINAHL,还有Cochrane.
    方法:按照PRISMA指南进行系统评价和荟萃分析。在筛选的1,185项研究中,95项儿科OT研究符合纳入标准。进行比例的Meta分析。
    结果:共分析了1224例OT患儿。不包括病例报告,OT后CVA的加权比例为0.31%(95%CI0.06-0.93).如果一个孩子没有神经缺陷,0.30%(95%CI0.05-0.95)出现新的神经功能缺损。在0.89%(95%CI0.16-2.74)的筛查CTA中发现ICA损伤。与未筛查CTA的儿童(0.42%[95%CI0.06-1.37])相比,筛查CTA的儿童CVA发生率无差异(0.52%[95%CI0.06-1.37])。发生CVA的患者损伤>2厘米的比例更高,后柱或扁桃体受伤,与没有CVA的患者相比,用书写器具或冰棒棒造成的伤害。
    结论:在维持OT后经历导致CVA的ICA损伤的儿童比例较低。CTA很少显示神经系统检查正常的儿童的ICA变化。与未接受CTA的儿童相比,接受CTA的儿童的CVA发生率并不明显较低。临床医生应根据个别儿童的陈述权衡CTA的风险和收益,并与护理人员讨论共同决策。喉镜,133:25-37,2023.
    To analyze the utility of computed tomography angiography (CTA) in identifying internal carotid artery (ICA) injury and reducing cerebrovascular accident (CVA) incidence in children presenting with normal neurologic exams after oropharyngeal trauma (OT).
    PubMed, Scopus, CINAHL, and Cochrane.
    A systematic review and meta-analysis were performed following PRISMA guidelines. Of 1,185 studies screened, 95 studies of pediatric OT met inclusion criteria. Meta-analysis of proportions was performed.
    A total of 1224 children with OT were analyzed. Excluding case reports, the weighted proportion of a CVA after OT was 0.31% (95% CI 0.06-0.93). If a child presented without neurologic deficits, 0.30% (95% CI 0.05-0.95) returned with new neurologic deficits. An ICA injury was identified in 0.89% (95% CI 0.16-2.74) of screening CTAs. No difference in CVA incidence was seen in children with screening CTA (0.52% [95% CI 0.02-2.15]) compared to children without screening CTA (0.42% [95% CI 0.06-1.37]). Patients who developed CVA had a higher proportion of injuries >2 cm, injuries at the posterior pillar or tonsil, and injuries with a writing utensil or popsicle stick compared to patients without CVA.
    The proportion of children experiencing an ICA injury leading to CVA after sustaining OT is low. CTAs infrequently show ICA changes in children with normal neurological exams. Children who receive CTAs do not have a significantly lower incidence of CVAs than children who do not receive CTAs. Clinicians should weigh the risks and benefits of a CTA based on an individual child\'s presentation and discuss this with caregivers for shared decision-making. Laryngoscope, 133:25-37, 2023.
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  • 文章类型: Journal Article
    The present study aims to develop an integrative review about pseudoaneurysms after traumatic facial trauma, through the analysis of its etiology, type of fracture, signs and symptoms, time elapsed between the trauma and the exposure of signs and symptoms, and treatment performed in these cases. Furthermore into the report, there are 3 clinical cases that occurred in the Buccomaxillofacial Surgery and Traumatology service of Hospital da Restauração Recife/PE. The study was carried out in 2 phases, first, a digital research about post-traumatic craniofacial pseudoaneurysm was performed in the following databases \"MEDLINE/PubMed,\" \"Scielo\" and \"Scopus,\" in September 2019, with 5 articles being included. In the second, 3 cases of patients with high-impact facial trauma who developed pseudoaneurysm of the internal carotid artery were reported. The average age of the patients was 35.6 years, all patients were male (100%), the majority (60%) being victims of an automobile accident, 3 patients (60%) suffered craniofacial trauma and 2 (40%) had trauma only to the face, most of them had symptoms later on due to the trauma, in 80% of cases the therapy instituted was embolization. Cases of high-impact craniofacial traumas, which present epistaxis and/or ophthalmological alterations correlated to fractures, should be carefully evaluated, determining a better prognosis for the patient.
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