未经批准:两种地方性水痘传染病,羊痘(SP)和山痘(GP)在亚洲很常见,非洲,和中东。绵羊和山羊,总的来说,被认为是小农户和边缘农户的流动资产,在肉类方面具有显著的经济价值,羊毛,和皮肤/皮革生产。印度的绵羊和山羊种群总数为14888万和7426万,分别。Capripox仅在马哈拉施特拉邦(印度)就造成了230万美元(印度卢比[INR]1.05亿美元)的经济损失,一群人花了6年的时间才从疫情中恢复过来。国家一级的预计年度损失为2747万美元(1250万卢比)。因此,羊痘疾病使小型和边缘农民承受着巨大的财务压力。本研究使用系统评价和荟萃分析估计了亚洲和非洲大陆SP和GP疾病的血清阳性率。研究结果将有助于研究人员和决策者了解疾病的时空分布及其负担。此外,研究结果也有助于设计和实施针对这些疾病的特定地点预防和根除措施。
UNASSIGNED:使用Cochran合作的系统评价和荟萃分析指南的首选报告项目进行系统评价,随后使用荟萃分析。文献是从各种数据库中收集的。初始搜索字符串使用关键字和布尔运算符(或不)星号*和引号的不同组合,在2000年至2020年期间产生了超过9000篇文章。在9398篇论文中,选择了80项研究,使用纳入和排除标准进行完整的测试综述和质量偏倚评估。最后,21篇文章用于荟萃分析。统计研究采用了使用R.
UNASSIGNED的固定效应和随机效应模型:SP和GP的血清阳性率是使用累积样本量为4352的研究计算的,其中绵羊和山羊的样本合计贡献了48%,其次是绵羊(32%)和山羊(21%)。元回归的结果显示,检测技术在5%水平(Qm=14.12)对总体效应大小具有显著影响。亚组分析的聚合酶链反应(PCR)测试与样品进一步分为两类基于中位数,它显示62%的样品使用PCR作为检测测试,然后是II组。
未经批准:从研究中,结论是SP和GP疾病高度流行;因此,有效疫苗,通过推广活动对农民进行适当的教育,和跨界疾病移动限制对于控制和根除疾病是必要的。
UNASSIGNED: Two endemic capripox infectious diseases, sheeppox (SP) and goatpox (GP) are common in Asia, Africa, and the Middle East. Sheep and goats, in general, are considered current assets of small and marginal farmers and have significant economic value in terms of meat, wool, and skin/hide production. Sheep and goat populations in India total 148.88 million and 74.26 million, respectively. Capripox caused US$ 2.3 million (Indian Rupee [INR] 105 million) in economic damages in Maharashtra (India) alone, and it took over 6 years for a flock to recover from the outbreak. The projected yearly loss at the national level is US$ 27.47 million (INR 1250 million). As a result, Capripox diseases put small and marginal farmers under much financial strain. The present study estimates the seroprevalence of SP and GP diseases in the Asian and African continents using systematic
review and meta-analysis. The results of the study will help researchers and policymakers to understand the spatial and temporal distribution of the disease and its burden. In addition, the results are also helpful to design and implement location-specific prevention and eradication measures against these diseases.
UNASSIGNED: Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines of Cochran collaborations were used for systematic
review and subsequently meta-analysis were used. The literature was collected from various databases. Initial search string resulted in more than nine thousand articles for the period 2000 to 2020 using the different combinations of keywords and Boolean operators (or not) asterisk* and quotation marks. Out of 9398 papers, 80 studies were chosen for complete test reviews and quality bias evaluation using the inclusion and exclusion criteria. Finally, 21 articles were used for the meta-analysis. The statistical study employed fixed effects and random effects models using R.
UNASSIGNED: Seroprevalence of SP and GP was calculated using studies with a cumulative sample size of 4352, out of which sheep and goats\' samples together contribute 48%, followed by sheep (32%) and goat (21%). The result of the meta-regression revealed that detection techniques had a significant impact on the overall effect size at 5% level (Qm=14.12). Subgroup analysis of polymerase chain reaction (PCR) test with samples was further grouped into two categories based on the median, and it revealed that 62% of samples used PCR as a detecting test followed by group-II.
UNASSIGNED: From the study, it is concluded that SP and GP diseases are highly prevalent; hence, effective vaccines, proper education to farmers through extension activity, and transboundary disease movement restriction are necessary for the control and eradication of the disease.