CLINICAL MEDICINE

临床医学
  • 文章类型: Practice Guideline
    背景:鉴于临床超声在医学中的应用越来越多,标准化其应用至关重要,培训,和研究。
    目的:本文件的目的是提供共识建议,以解决有关临床超声单元的实践和操作的问题。来自临床超声先进单位的19名专家和领导参加了会议。采用改进的德尔菲共识法。
    结果:共有137份共识声明,根据证据和专家意见,被考虑。声明分布在10个地区,99项建议达成共识。
    结论:这一共识定义了临床超声在内科领域的最重要方面,目的是在各个方面规范和促进这种医疗保健进步。该文件由临床超声工作组编写,并得到西班牙内科学会的认可。
    BACKGROUND: Given the increasing adoption of clinical ultrasound in medicine, it is essential to standardize its application, training, and research.
    OBJECTIVE: The purpose of this document is to provide consensus recommendations to address questions about the practice and operation of clinical ultrasound units. Nineteen experts and leaders from advanced clinical ultrasound units participated. A modified Delphi consensus method was used.
    RESULTS: A total of 137 consensus statements, based on evidence and expert opinion, were considered. The statements were distributed across 10 areas, and 99 recommendations achieved consensus.
    CONCLUSIONS: This consensus defines the most important aspects of clinical ultrasound in the field of Internal Medicine, with the aim of standardizing and promoting this healthcare advancement in its various aspects. The document has been prepared by the Clinical Ultrasound Working Group and endorsed by the Spanish Society of Internal Medicine.
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  • 文章类型: Journal Article
    在2019年冠状病毒病大流行期间,远程医疗已经从治疗医院有限的患者的方式转变为治疗非紧急情况的必要方法。远程医疗有两种方式,即“混合医疗”和“网关医疗”,“它利用了在线医疗的特点,并可能在不久的将来变得重要。在混合医疗期间,患者及其初级保健医生在接受面对面医疗的同时,由专科医生通过远程医疗进行检查,导致当地医疗水平的整体提高和可治疗疾病数量的增加。Gateway医疗实践是一种远程医疗形式,用于拒绝或不接受面对面医疗护理的患者与医生进行咨询。远程医疗允许医生确定疾病的严重程度和分诊患者,同时减少不必要的家访,紧急住院和感染的传播。远程医疗不如亲自医疗,并允许与其他医疗保健提供商更轻松地合作。然而,远程医疗对于需要明确诊断和全面了解患者病史的情况并不是最佳选择。它受到患者使用远程医疗设备的能力的限制,以及意外治疗和欺诈的风险。远程医疗的使用可能会导致新的发展,在线综合老年评估工具和技术。GeriatrGerontolInt2022;22:913-916。
    Telemedicine has changed from a way to treat patients with limited access to hospitals to a necessary method of treatment for non-urgent conditions during the coronavirus disease 2019 pandemic. There are two styles of telemedicine, namely \"hybrid medical care\" and \"gateway medical care,\" which take advantage of the characteristics of online medical care and might become important in the near future. During hybrid medical care, a patient and their primary care physician have face-to-face medical care while simultaneously being examined by a specialist physician through telemedicine, leading to an overall improvement in the level of local medical care and expansion in the number of treatable diseases. Gateway medical practice is a form of telemedicine used for patients who would otherwise refuse or not receive in-person medical care to engage in consultation with a physician. Telemedicine allows physicians to determine disease severity and triage patients, while reducing unnecessary home visits, emergency hospitalizations and the spread of infection. Telemedicine is less intense than in-person medical care, and allows for easier collaboration with other healthcare providers. However, telemedicine is not optimal for conditions requiring a definitive diagnosis and a comprehensive understanding of the patient\'s medical history. It is limited by the patient\'s ability to use telemedicine devices, and the risk of accidental treatments and fraud. The use of telemedicine might result in the development of new, online comprehensive geriatric assessment tools and technologies. Geriatr Gerontol Int 2022; 22: 913-916.
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  • 文章类型: Letter
    暂无摘要。
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  • 文章类型: Journal Article
    本文将日本外科学会(JSS)和日本解剖学协会于2012年发布的尸体手术训练指南(CST)从日语翻译成英语。这些指南基于日本法律,并允许将捐赠的尸体用于CST和临床研究。以下是实施准则中概述的活动的条件。目的是改善医学并为社会福利做出贡献。活动只能在日本法律规定下,在解剖学部门的集中控制下在医学或牙科大学进行。在使用尸体时,注册捐赠者必须提供书面知情同意书,以将其身体用于CST和其他临床医学活动。强烈禁止将尸体和以利润为基础的CST用于商业。此外,除商业性活动外,所有与尸体相关的活动都需要大学机构审查委员会(IRB)的批准才能实施。每所大学为实施科技委而组织的专家委员会应总结方案的实施情况,并报告培训方案的细节,运营成本,和JSS科技委促进委员会的利益冲突。
    This article translates the guidelines for cadaver surgical training (CST) published in 2012 by Japan Surgical Society (JSS) and Japanese Association of Anatomists from Japanese to English. These guidelines are based on Japanese laws and enable the usage of donated cadavers for CST and clinical research. The following are the conditions to implement the activities outlined in the guidelines. The aim is to improve medicine and to contribute to social welfare. Activities should only be carried out at medical or dental universities under the centralized control by the department of anatomy under the regulation of Japanese law. Upon the usage of cadavers, registered donors must provide a written informed-consent for their body to be used for CST and other activities of clinical medicine. Commercial use of cadavers and profit-based CST is strongly prohibited. Moreover, all the cadaver-related activities except for the commercial-based ones require the approval of the University\'s Institutional Review Board (IRB) before implementation. The expert committee organized at each university for the implementation of CST should summarize the implementation of the program and report the details of the training program, operating costs, and conflicts of interest to the CST Promotion Committee of JSS.
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  • 文章类型: Journal Article
    本文将日本外科学会(JSS)和日本解剖学协会于2012年发布的尸体手术训练指南(CST)从日语翻译成英语。这些指南基于日本法律,并允许将捐赠的尸体用于CST和临床研究。以下是实施准则中概述的活动的条件。目的是改善医学并为社会福利做出贡献。活动只能在日本法律规定下,在解剖学部门的集中控制下在医学或牙科大学进行。在使用尸体时,注册捐赠者必须提供书面知情同意书,以将其身体用于CST和其他临床医学活动。强烈禁止将尸体和以利润为基础的CST用于商业。此外,除商业性活动外,所有与尸体相关的活动都需要大学机构审查委员会(IRB)的批准才能实施。每所大学为实施科技委而组织的专家委员会应总结方案的实施情况,并报告培训方案的细节,运营成本,和JSS科技委促进委员会的利益冲突。
    This article translates the guidelines for cadaver surgical training (CST) published in 2012 by Japan Surgical Society (JSS) and Japanese Association of Anatomists from Japanese to English. These guidelines are based on Japanese laws and enable the usage of donated cadavers for CST and clinical research. The following are the conditions to implement the activities outlined in the guidelines. The aim is to improve medicine and to contribute to social welfare. Activities should only be carried out at medical or dental universities under the centralized control by the department of anatomy under the regulation of Japanese law. Upon the usage of cadavers, registered donors must provide a written informed-consent for their body to be used for CST and other activities of clinical medicine. Commercial use of cadavers and profit-based CST is strongly prohibited. Moreover, all the cadaver-related activities except for the commercial-based ones require the approval of the University\'s Institutional Review Board (IRB) before implementation. The expert committee organized at each university for the implementation of CST should summarize the implementation of the program and report the details of the training program, operating costs, and conflicts of interest to the CST Promotion Committee of JSS.
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  • 文章类型: Editorial
    临床医学中的人工智能(AI)包括物理机器人和设备以及虚拟AI和机器学习。人们对在手术中使用人工智能的伦理问题提出了担忧,包括手术决策的指导,患者保密,以及使用这些方法需要对照临床试验的支持,以便制定临床指南。虚拟AI最常见的应用包括疾病诊断,健康监测和数字病人咨询,临床培训,患者数据管理,药物开发,个性化医疗。2020年9月,CONSORT-A1扩展开发了14个额外的项目,这些项目应该为人工智能研究报告,包括对人工智能干预的明确描述。所需技能,研究设置,人工智能干预的输入和输出,分析错误,以及人类和人工智能的互动。这篇社论旨在介绍人工智能在临床医学中的当前应用和挑战,以及新的2020CONSORT-AI研究指南的重要性。
    Artificial intelligence (AI) in clinical medicine includes physical robotics and devices and virtual AI and machine learning. Concerns have been raised regarding ethical issues for the use of AI in surgery, including guidance for surgical decisions, patient confidentiality, and the need for support from controlled clinical trials to use these methods so that clinical guidelines can be developed. The most common applications for virtual AI include disease diagnosis, health monitoring and digital patient consultations, clinical training, patient data management, drug development, and personalized medicine. In September 2020, the CONSORT-A1 extension was developed with 14 additional items that should be reported for AI studies that include clear descriptions of the AI intervention, skills required, study setting, inputs and outputs of the AI intervention, analysis of errors, and the human and AI interactions. This Editorial aims to present current applications and challenges of AI in clinical medicine and the importance of the new 2020 CONSORT-AI study guidelines.
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  • 文章类型: Journal Article
    Viral lower respiratory tract infection (VLRTI) is the most common cause of hospital admission among small children in high-income countries. Guidelines to identify children in need of admission are lacking in the literature. In December 2012, our hospital introduced strict guidelines for admission. This study aims to retrospectively evaluate the safety and efficacy of the guidelines. We performed a single-center retrospective administrative database search and medical record review. ICD-10 codes identified children < 24 months assessed at the emergency department for VLRTI for a 10-year period. To identify adverse events related to admission guidelines implementation, we reviewed patient records for all those discharged on primary contact followed by readmission within 14 days. During the study period, 3227 children younger than 24 months old were assessed in the ED for VLRTI. The proportion of severe adverse events among children who were discharged on their initial emergency department contact was low both before (0.3%) and after the intervention (0.5%) (p=1.0). Admission rates before vs. after the intervention were for previously healthy children > 90 days 65.3% vs. 53.3% (p<0.001); for healthy children ≤ 90 days 85% vs. 68% (p<0.001); and for high-risk comorbidities 74% vs. 71% (p=0.5).Conclusion: After implementation of admission guidelines for VLRTI, there were few adverse events and a significant reduction in admissions to the hospital from the emergency department. Our admission guidelines may be a safe and helpful tool in the assessment of children with VLRTI. What is Known: • Viral lower respiratory tract infection, including bronchiolitis, is the most common cause of hospitalization for young children in the developed world. Treatment is mainly supportive, and hospitalization should be limited to the cases in need of therapeutic intervention. • Many countries have guidelines for the management of the disease, but the decision on whom to admit for inpatient treatment is often subjective and may vary even between physicians in the same hospital. What is New: • Implementation of admission criteria for viral lower respiratory tract infection may reduce the rate of hospital admissions without increasing adverse events.
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  • 文章类型: Journal Article
    In 2020, the World Health Organization (WHO) released global guidelines on physical activity (PA) and sedentary behavior, for the first time providing population-based recommendations for people living with selected chronic conditions. This article briefly presents the guidelines, related processes and evidence, and, importantly, considers how they may be used to support research, practice, and policy.
    A brief overview of the scope, agreed methods, selected chronic conditions (adults living with cancer, hypertension, type 2 diabetes, and human immunodeficiency virus), and appraisal of systematic review evidence on PA/sedentary behavior is provided. Methods were consistent with World Health Organization protocols for developing guidelines.
    Moderate to high certainty evidence (varying by chronic condition and outcome examined) supported that PA can reduce the risk of disease progression or premature mortality and improve physical function and quality of life in adults living with chronic conditions. Direct evidence on sedentary behavior was lacking; however, evidence extrapolated from adult populations was considered applicable, safe, and likely beneficial (low certainty due to indirectness).
    Clinical and public health professionals and policy makers should promote the World Health Organization 2020 global guidelines and develop and implement services and programs to increase PA and limit sedentary behavior in adults living with chronic conditions.
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  • 文章类型: Journal Article
    For the purpose of examining the characteristics of dyslipidemia and fatty liver in patients with Werner syndrome in Japan in recent years, we searched all case reports of Japanese Werner syndrome reported on Medical Online and PubMed since 1996, and collected and examined the data and clinical features described in these reports. In addition, as there are few descriptions of treatment methods in these reports from Medical Online and PubMed, we analyzed 12 cases for which detailed data on treatment methods are available at Chiba University. Geriatr Gerontol Int 2021; 21: 133-138.
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  • 文章类型: Journal Article
    OBJECTIVE: To evaluate the characteristics of diabetes associated with Werner syndrome.
    METHODS: A literature search was done with search term \"Werner syndrome\" and \"Diabetes\".
    CONCLUSIONS: Prevalence of diabetes is extremely high in Werner syndrome. Diabetes associated with Werner syndrome is classified as \"accompanied with other diseases and conditions and the one occurring mainly in association with other genetic syndromes.\" This type of diabetes is marked by accumulated visceral fat and high insulin resistance, despite low body mass index. Thiazolidine derivatives and metformin are effective for glycemic control. New antidiabetic drugs, such as dipeptidyl peptidase-4 inhibitors and glucagon-like peptide-1 receptor agonists, could be potentially beneficial for patients with Werner syndrome. Furthermore, the establishment of diet therapy as well as exercise therapy is warranted. Geriatr Gerontol Int 2021; 21: 142-145.
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