当两种疾病都存在于单个患者中时,纤维肌痛可以影响哮喘的控制。
探讨伴随纤维肌痛患者的哮喘特征,以评估纤维肌痛是否是影响哮喘控制不良的哮喘严重程度的独立因素。我们还评估了患者对呼吸困难的感知,以证明气道阻塞感知的改变可能是哮喘控制不佳的原因。
这是一项横断面病例对照多中心研究,其中哮喘和纤维肌痛组中的56例患者与36例哮喘患者按性别匹配,大概年龄,和哮喘严重程度。所有患者均为女性。研究变量包括哮喘控制测试(ACT),迷你哮喘生活质量问卷(MiniAQLQ),奈梅亨过度换气综合征问卷,医院焦虑和抑郁量表,以及急性支气管收缩后呼吸困难的感觉。
虽然两个研究组的患者表现出相似的哮喘严重程度和抗哮喘药物的使用,哮喘和纤维肌痛组的患者在ACT和MiniAQLQ问卷上得分较低,与没有纤维肌痛的哮喘患者相比,焦虑和抑郁以及过度通气的得分更高。所有这些差异具有统计学意义。
哮喘患者的纤维肌痛影响呼吸系统疾病控制不良,并与呼吸困难的感觉改变有关。过度通气综合征,抑郁和焦虑的患病率很高,生活质量受损。
纤维肌痛可能被认为是同时患有哮喘和纤维肌痛的患者不受控制的哮喘的危险因素。
Fibromyalgia can affect the control of asthma when both diseases are present in a single patient.
To characterize asthma in patients with concomitant fibromyalgia to assess whether fibromyalgia is an independent factor of asthma severity that influences poor asthma control. We also evaluated how dyspnea is perceived by patients in order to demonstrate that alterations in the perception of airway obstruction may be responsible for poor asthma control.
This was a cross-sectional
case-control multicenter study, in which 56 patients in the asthma and fibromyalgia group were matched to 36 asthmatics by sex, approximate age, and asthma severity level. All patients were women. Study variables included the Asthma Control Test (ACT), the Mini Asthma Quality of Life Questionnaire (MiniAQLQ), the Nijmegen hyperventilation syndrome questionnaire, the Hospital Anxiety and Depression Scale, and perception of dyspnea after acute
bronchoconstriction.
Although patients in both study groups showed similar asthma severity and use of anti-asthmatic drugs, patients in the asthma and fibromyalgia group showed lower scores on the ACT and MiniAQLQ questionnaires, and higher scores of anxiety and depression as well as hyperventilation compared to asthma patients without fibromyalgia. All these differences were statistically significant.
Fibromyalgia in patients with asthma influences poor control of the respiratory disease and is associated with altered perception of dyspnea, hyperventilation syndrome, high prevalence of depression and anxiety, and impaired quality of life.
Fibromyalgia may be considered a risk factor for uncontrolled asthma in patients suffering from asthma and fibromyalgia concomitantly.