本研究旨在探讨乳腺密度与乳腺癌手术疗效的关系。PubMed,Scopus,WebofScience,科学直接,和Wiley图书馆进行了相关文献的系统搜索。在整个综合过程中都采用了RayyanQRCI。我们的结果包括10项研究,总共5017名被诊断患有乳腺癌的女性。随访时间为1年至15.1年。纳入的12项研究中有8项报告乳房低密度与无局部复发显著相关。异时对侧乳腺癌,在术前和术中阶段的挑战较少。另一方面,四项研究报告说,乳房X线摄影乳腺密度与疾病复发无关,生存,再切除,或不完全的临床和病理反应。低乳房X线摄影乳腺密度和术前和术中阶段的挑战减少之间存在显着关联,以及没有局部复发和较少的乳房切除术病例。然而,乳腺密度和疾病复发之间的联系,生存,再切除,不完全的临床和病理反应不太清楚,一些研究报告没有显著的关联。研究结果表明,乳房X线摄影乳腺密度可能在乳腺癌预后的某些方面发挥作用,但是需要进一步的研究来充分了解其影响。
This study aims to investigate the relationship between mammographic breast density and the surgical outcomes of breast cancer. PubMed, SCOPUS, Web of Science, Science Direct, and the Wiley Library were systematically searched for relevant literature. Rayyan QRCI was employed throughout this comprehensive process. Our results included ten studies with a total of 5017 women diagnosed with breast cancer. The follow-up duration ranged from 1 year to 15.1 years. Eight out of the twelve included studies reported that low mammographic breast density was significantly associated with no local recurrence, metachronous contralateral breast cancer, and fewer challenges in the preoperative and intraoperative phases. On the other hand, four studies reported that mammographic breast density is not linked to disease recurrence, survival, re-excision, or an incomplete clinical and pathological response. There is a significant association between low mammographic breast density and reduced challenges in the preoperative and intraoperative phases, as well as no local recurrence and fewer mastectomy cases. However, the link between mammographic breast density and disease recurrence, survival, re-excision, and incomplete clinical and pathological response is less clear, with some studies reporting no significant association. The findings suggest that mammographic breast density may play a role in certain aspects of breast cancer outcomes, but further research is needed to fully understand its impact.