Recently, research based on new biomaterials for stabilizing metallic nanoparticles has increased due to their greater environmental friendliness and lower health risk. Their stability is often a critical factor influencing their performance and shelf life. Nowadays, the use of biosurfactants is gaining interest due to their sustainable advantages. Biosurfactants are used for various commercial and industrial applications such as food processing, therapeutic applications, agriculture, etc. Biosurfactants create stable coatings surrounding nanoparticles to stop agglomeration and provide long-term stability. The present review study describes a collection of important scientific works on stabilization and capping of metallic nanoparticles as biosurfactants. This review also provides a comprehensive overview of the intrinsic properties and environmental aspects of metal nanoparticles coated with biosurfactants. In addition, future methods and potential solutions for biosurfactant-mediated stabilization in nanoparticle synthesis are also highlighted. The objective of this study is to ensure that the stabilized nanoparticles exhibit biocompatible properties, making them suitable for applications in medicine and biotechnology.

Biosurfactants are natural compounds with remarkable surface-active properties that may offer an eco-friendly alternative to conventional surfactants. Among them, mannosylerythritol lipids (MELs) stand out as an intriguing example of a glycolipid biosurfactant. MELs have been used in a variety of sectors for various applications, and are currently commercially produced. Industrially, they are used in the pharmaceutical, cosmetic, food, and agricultural industries, based on their ability to reduce surface tension and enhance emulsification. However, despite their utility, their production is comparatively limited industrially. From a bioprocessing standpoint, two areas of interest to improve the production process are upstream production and downstream (separation and purification) product recovery. The former has seen a significant amount of research, with researchers investigating several production factors: the microbial species or strain employed, the producing media composition, and the production strategy implemented. Improvement and optimization of these are key to scale-up the production of MELs. On the other hand, the latter has seen comparatively limited work presented in the literature. For the most part traditional separation techniques have been employed. This systematic review presents the production and purification methodologies used by researchers by comprehensively analyzing the current state-of-the-art with regards the production, separation, and purification of MELs. By doing so, the review presents different possible approaches, and highlights some potential areas for future work by identifying opportunities for the commercialization of MELs.

Green dispersants are so-called \"green\" because they are renewable (from bio-based sources), non-volatile (from ionic liquids), or are from naturally available solvents (vegetable oils). In this review, the effectiveness of different types of green dispersants, namely, protein isolates and hydrolysates from fish and marine wastes, biosurfactants from bacterial and fungal strains, vegetable-based oils such as soybean lecithin and castor oils, as well as green solvents like ionic liquids are reviewed. The challenges and opportunities offered by these green dispersants are also elucidated. The effectiveness of these dispersants varies widely and depends on oil type, dispersant hydrophilicity/hydrophobicity, and seawater conditions. However, their advantages lie in their relatively low toxicity and desirable physico-chemical properties, which make them potentially ecofriendly and effective dispersants for future oil spill response.

Microbial synthesized surfactants are used in contaminated soil bioremediation processes and have multiple applications in various industries. These compounds minimize the negative influences in soil via absorption by detoxifying the toxic metals or compounds. Further, applications of biosurfactants are detected in treating chronic diseases or synthetic drugs alternatives in current periods. Various surfactant molecules can provide many benefits due to their diversities in structural and functional groups. These compounds showed a wide array of applications in multiple sectors such as biomedical or pharmaceutical fields. Agricultural, food processing, laundry, or other sectors. Many microbial systems or plant cells are utilized in biosurfactant production as confirmed by biochemical analysis of genome sequencing tools. Biosurfactant compounds can alter drug transport across the cell membrane. Different nature of biosurfactant compounds exhibited their antifungal, antibacterial, antiviral activities, or antiadhesive coating agents used in reduction of many hospital infections. These distinct properties of biosurfactants pushed their broad spectrum applications in biomedical, agriculture sectors and bioremediation tasks. Additionally, many strains of fungi or bacteria are utilized for biosurfactant synthesis involved in the detoxification of soil/other components of the environment. In these reviews, authors explained various biosurfactants molecules and their mode of actions. Also, applications of microbial originated biosurfactants along with their process technologies are described. Future perspectives of biosurfactants and their scope are also critically explained so that this review paper can be used as a showcase for production and application of biosurfactants.

This review discusses the classification, characteristics, and applications of biosurfactants. The biosynthesis pathways for different classes of biosurfactants are reviewed. An in-depth analysis of reported research is carried out emphasizing the synthetic pathways, culture media compositions, and influencing factors on production yield of biosurfactants. The environmental, pharmaceutical, industrial, and other applications of biosurfactants are discussed in detail. A special attention is given to the biosurfactants application in combating the pandemic COVID-19. It is found that biosurfactant production from waste materials can play a significant role in enhancing circular bioeconomy and environmental sustainability. This review also details the life cycle assessment methodologies for the production and applications of biosurfactants. Finally, the current status and limitations of biosurfactant research are discussed and the potential areas are highlighted for future research and development. This review will be helpful in selecting the best available technology for biosynthesis and application of particular biosurfactant under specific conditions.

Microbial biosurfactants are low-molecular-weight surface-active compounds of high industrial interest owing to their chemical properties and stability under several environmental conditions. The chemistry of a biosurfactant and its production cost are defined by the selection of the producer microorganism, type of substrate, and purification strategy. Recently, biosurfactants have been applied to solve or contribute to solving some environmental problems, with this being their main field of application. The most referenced studies are based on the bioremediation of contaminated soils with recalcitrant pollutants, such as hydrocarbons or heavy metals. In the case of heavy metals, biosurfactants function as chelating agents owing to their binding capacity. However, the mechanism by which biosurfactants typically act in an environmental field is focused on their ability to reduce the surface tension, thus facilitating the emulsification and solubilization of certain pollutants (in-situ biostimulation and/or bioaugmentation). Moreover, despite the low toxicity of biosurfactants, they can also act as biocidal agents at certain doses, mainly at higher concentrations than their critical micellar concentration. More recently, biosurfactant production using alternative substrates, such as several types of organic waste and solid-state fermentation, has increased its applicability and research interest in a circular economy context. In this review, the most recent research publications on the use of biosurfactants in environmental applications as an alternative to conventional chemical surfactants are summarized and analyzed. Novel strategies using biosurfactants as agricultural and biocidal agents are also presented in this paper.

Biosurfactants are considered as an environmentally friendly and sustainable alternative to conventional fossil-derived and chemically produced surfactants. Their production pathways, physicochemical properties, and applications are widely researched and discussed in literature. In this context, investigating the different impacts from the entire life cycle of biosurfactants is important to understand and mitigate potential environmental hotspots. Life Cycle Assessment (LCA) is an internationally accepted and standardized methodology to analyze the environmental impacts of products from a holistic view. Therefore, this study provides a detailed overview of existing LCA studies of biosurfactants by means of a systematic literature research. The focus specifically lies on articles that investigated microbial biosurfactants. However, the systematic approach used ensured a broader overview related to bio-based surfactants as well. Furthermore, two related topics, ecotoxicity and biodegradability of biosurfactants, were identified and discussed based on the search findings. After screening over 2,500 documents using Scopus and Google Scholar, six relevant LCA articles of biosurfactants could be identified. The identified articles are divided into LCA studies of alkyl polyglycosides, chemically produced bio-based surfactants, and LCA studies of microbial biosurfactants, their content analyzed and discussed in context. In conclusion, the number of available LCA studies is very limited and their results are often not comparable. To the best of the authors\' knowledge, this review is the first of its kind to provide a detailed overview of LCA studies of biosurfactants. Consequently, the need for implementing more LCA studies becomes clear.

Polycyclic aromatic hydrocarbons (PAHs) are hazardous environmental pollutants with widespread and well-recognized health concerns. Amidst more than a hundred known PAHs, 16 are categorized as priority pollutants. Use of widely diverse biological machinery comprising bacteria, fungi, and algae harnessed from contaminated sites has emerged as an ecologically safe and sustainable approach for PAH degradation. The potential of these biological systems has been thoroughly examined to maximize the degradation of specific PAHs by understanding their detailed biochemical pathways, enzymatic system, and gene organization. Recent advancements in microbial genetic engineering and metabolomics using modern analytical tools have facilitated the bioremediation of such xenobiotics. This review explores the role of microbes, their biochemical pathways, genetic regulation of metabolic pathways, and the effect of biosurfactants against the backdrop of PAH substrate structures.

Transportation of crude oil and refined petroleum is the main function of pipeline system in petroleum industry. Unfortunately, wax precipitation has become a serious problem for the petroleum industry where it causes pipeline blockage and eventually results in operational catastrophe. Up-to-date, the technique used to mitigate wax deposition by injecting chemical wax inhibiting agent remains a debate amongst researchers. This review addresses the evolution of chemical wax inhibitor generations started from polymer-based in the early 1980s, followed by biosurfactant-based in the late 1990s and finally plant-based or agricultural-based in recent years. Pivoting to environmental impact, petroleum industry is amidst finding a green wax inhibiting agent to solve wax deposition problem that occurs during the transportation of crude oil whilst facilitating the remediation process of contaminated groundwater.

Psoriasis is a skin disease that is not lethal and does not spread through bodily contact. However, this seemingly harmless condition can lead to a loss of confidence and social stigmatization due to a persons\' flawed appearance. The conventional methods of psoriasis treatment include taking in systemic drugs to inhibit immunoresponses within the body or applying topical drugs onto the surface of the skin to inhibit cell proliferation. Topical methods are favored as they pose lesser side effects compared to the systemic methods. However, the side effects from systemic drugs and low bioavailability of topical drugs are the limitations to the treatment. The use of nanotechnology in this field has enhanced drug loading capacity and reduced dosage size. In this review, biosurfactants were introduced as a \'greener\' alternative to their synthetic counterparts. Glycolipid biosurfactants are specifically suited for anti-psoriatic application due to their characteristic skin-enhancing qualities. The selection of a suitable oil phase can also contribute to the anti-psoriatic effect as some oils have skin-healing properties. The review covers the pathogenic pathway of psoriasis, conventional treatments, and prospective ingredients to be used as components in the nanoemulsion formulation. Furthermore, an insight into the state-of-the-art methods used in formulating nanoemulsions and their progression to low-energy methods are also elaborated in detail.