背景:胃淋巴瘤是儿童中极为罕见的疾病;通常表现为非特异性症状,这使得大多数病例的诊断相对较晚。在这里,我们介绍了一例儿童胃原发性淋巴母细胞B细胞淋巴瘤。
方法:一名14岁女性出现腹部不适3个月。在检查中,她有一个活动的上腹部肿块。CT腹部显示肿块占据胃的较小曲率,内窥镜检查证实了这一点。进行了胃大部切除术。标本的组织病理学和流式细胞术,骨髓检查证实了原发性B细胞淋巴母细胞胃淋巴瘤的诊断。
结论:原发性胃淋巴瘤,特别是,是一种非常罕见的胃肿瘤。此外,报道的大多数病例是成熟的B细胞淋巴瘤亚型.儿童的临床表现与其他类型的原发性胃恶性肿瘤相同。此外,对于儿科年龄组的此类病症的管理,目前尚无指南.在我们的案例中,进行了手术切除;由于最初的内窥镜活检怀疑腺癌,进一步的检查证实了胃原发性淋巴母细胞B细胞淋巴瘤的诊断。
结论:儿童胃恶性肿瘤的早期发现是预后的关键因素。此外,最佳的手术切除显示出非常好的结果。
BACKGROUND: Gastric lymphoma is an extremely rare disease in children; it is usually presented with non-specific symptoms, which makes the diagnosis relatively late in most cases. Here we present a
case of a primary lymphoblastic B-cell lymphoma of the stomach in a child.
METHODS: A 14 -year- old female presented with abdominal discomfort for three months. On examination, she had a mobile epigastric mass. The CT abdomen showed a mass occupying the lesser curvature of the stomach, which was confirmed by the endoscopy. A subtotal gastrectomy was carried out. Histopathology and flow cytometry for the specimen, along with bone marrow examination confirmed the diagnosis of primary B-cell lymphoblastic gastric lymphoma.
CONCLUSIONS: Primary gastric lymphoma, in particular, is a very rare gastric neoplasm. Furthermore, most of the reported cases are mature B-cell lymphoma subtypes. The clinical presentation in children is the same as for other types of primary gastric malignancies. Moreover, no guidelines are available for the management of such conditions in the paediatric age group. In our
case, a surgical resection was carried out; as the initial endoscopic biopsy was suspicious for adenocarcinoma, further workup confirmed the diagnosis of primary lymphoblastic B-cell lymphoma of the stomach.
CONCLUSIONS: Early detection of gastric malignancies in children is a key element in the prognosis. In addition, optimal surgical resection showed a very good outcome.