Arterial Occlusive Diseases

动脉闭塞性疾病
  • 文章类型: Case Reports
    背景技术脑血管闭塞是与中风相关的关键健康问题。世界范围内的主要死亡原因。大血管闭塞,构成急性缺血性中风的重要部分,呈现严重的患者结果。涉及多个颅外血管的阻塞很少见,但由于可能没有明显的症状,因此在早期发现方面存在挑战。病例报告:一名65岁的男性,有明显的吸烟史,没有高血压或心血管疾病史,表现为每天4至5次复发性全身强直性癫痫发作。尽管神经系统检查正常,颈部超声检查提示颈动脉和椎动脉有潜在的阻塞.常规血管造影显示轻度冠状动脉斑块,但来自主动脉的所有颅分支完全闭塞。在瓷主动脉旁边.颈部CT血管造影证实主动脉主动脉上分支完全闭塞,右颈内动脉缺失,左侧颈内动脉近端闭塞的证据。由于患者病情稳定,因此无需手术干预即可进行医疗管理。他的药物治疗方案包括抗血小板治疗和他汀类药物出院。四个月的随访显示症状明显改善,CT显示脑血流循环变化最小。结论该案例强调了大脑在承受严重血管挑战方面的显着适应能力。罕见的多发颅外血管闭塞和瓷主动脉的存在进一步使病例复杂化。利用先进的成像技术和个性化治疗方法对于管理复杂的血管状况至关重要。在这种情况下,持续的研究和仔细的监测对于促进理解和管理至关重要。
    BACKGROUND Cerebrovascular occlusion is a critical health concern associated with strokes, a leading cause of mortality worldwide. Large vessel occlusion, constituting a significant portion of acute ischemic strokes, presents serious patient outcomes. Occlusions involving multiple extracranial vessels are rare but pose challenges in early detection due to potential absence of overt symptoms. CASE REPORT A 65-year-old man with a significant smoking history and no prior history of hypertension or cardiovascular disease presented with recurrent generalized tonic seizures occurring 4 to 5 times daily. Despite normal neurological examinations, neck sonography indicated potential obstruction in the carotid and vertebral arteries. Conventional angiography revealed mild coronary artery plaques but complete occlusion of all cranial branches originating from the aorta, alongside porcelain aorta. Neck CT angiography confirmed complete occlusion of the supra-aortic branches of the aorta and absence of the right internal carotid artery, with evidence of proximal occlusion of the left internal carotid artery. Medical management without surgical intervention was pursued due to the patient\'s stable condition. He was discharged with a medication regimen including antiplatelet therapy and statins. Four-month follow-up showed significant symptom improvement, with minimal changes in brain blood flow circulation noted on CT. CONCLUSIONS This case underscores the brain\'s remarkable adaptive capacity in withstanding severe vascular challenges. The rarity of multiple extracranial vessel occlusions and presence of porcelain aorta further complicated the case. Utilizing advanced imaging techniques and personalized treatment approaches are crucial in managing complex vascular conditions. Ongoing research and careful monitoring are essential to advance understanding and management in such cases.
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  • 文章类型: Case Reports
    背景:水痘带状疱疹病毒(VZV)的再激活导致带状疱疹(HZ),这是一种疼痛的单侧皮疹,具有典型的皮肤分布。HZ后可能会出现带状疱疹后遗神经痛(PHN),血管病变,脊髓病,视网膜坏死,和小脑炎.血管病变可引起缺血性卒中,动脉瘤,动脉夹层,短暂性脑缺血发作,很少,外周动脉疾病(PAD)。可能的机制是VZV通过感觉神经节传播到动脉,导致炎症和病理性血管重塑,导致血管病变.
    方法:这里,我们描述了HZ后5年的罕见股动脉闭塞引起的血管病变。一名65岁的妇女在3个月前发生的HZ后持续疼痛到我们的疼痛诊所就诊。她的右大腿上有几处皮疹疤痕,并持续跳动,射击,和剧烈的疼痛。患者被诊断为PHN,并服用了缓解腿部疼痛的药物。症状持续了近5年。她再次抱怨右大腿阵发性刺痛感和由于疼痛加剧而导致的跛行,这是在6个月前开始的。她报告步行10分钟后腿部疼痛。腰椎磁共振成像(MRI)显示右侧L2水平椎间孔狭窄,L2以下无异常。随后,对患者的血管疾病进行了评估。下肢超声和计算机断层扫描(CT)血管造影显示右股浅动脉和胫骨动脉以及左股中动脉和胫骨动脉狭窄和血栓闭塞。双侧通过经皮血管成形术进行手术血运重建。术后腿部疼痛缓解,跛行好转。
    结论:周围动脉闭塞是HZ后的一种罕见现象。在涉及HZ症状变化的病例中,潜在的血管病变需要进一步评估.
    BACKGROUND: Reactivation of the varicella zoster virus (VZV) results in herpes zoster (HZ), which is a painful unilateral rash with a typical dermatomal distribution. HZ may be followed by postherpetic neuralgia (PHN), vasculopathy, myelopathy, retinal necrosis, and cerebellitis. Vasculopathy can cause ischemic stroke, aneurysms, arterial dissection, transient ischemic attack, and rarely, peripheral arterial disease (PAD). The possible mechanism is that the VZV travels to the arteries through the sensory ganglia, leading to inflammation and pathological vascular remodeling, which result in vasculopathy.
    METHODS: Here, we describe a rare case of femoral artery occlusion induced vasculopathy 5 years after HZ. A 65-year-old woman visited our pain clinic with persistent pain following HZ that occurred 3 months earlier. She had several rash scars on the right thigh along with a continuous throbbing, shooting, and sharp pain. The patient was diagnosed with PHN and prescribed with medications that relieved the leg pain. The symptoms remained stationary for almost 5 years. She presented again with complaints of a paroxysmal tingling sensation in the right thigh and claudication due to increased pain, which had begun 6 months prior. She reported leg pain after walking for 10 minutes. Lumbar spine magnetic resonance imaging (MRI) revealed foraminal stenosis at the level of right L2, with no abnormality below L2. Subsequently, the patient was evaluated for vascular diseases. Lower extremity ultrasonography and computed tomography (CT) angiography revealed stenosis and thrombotic occlusions in the right superficial femoral and tibial arteries as well as the left middle femoral and tibial arteries. Surgical revascularization via percutaneous angioplasty was performed bilaterally. The leg pain was relieved after the procedure and the claudication improved.
    CONCLUSIONS: Peripheral artery occlusion is a rare phenomenon following HZ. In cases involving changes in HZ symptoms, further evaluation is required for potential vasculopathy.
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  • 文章类型: Journal Article
    背景:椎动脉残端综合征(VASS)是急性卒中的一个原因。由于VASS发病机制的特殊性,VASS的介入治疗是困难的。常见的机械血栓切除术方法包括股动脉和桡动脉方法。然而,传统的方法可能不适合VASS。如果不采取有效措施及时开放违规船只,这可能导致高残疾率。近年来,关于治疗VASS的手术方法尚未达成共识。
    方法:患者就诊于急诊科,有2小时意识障碍史。
    方法:经过神经和磁共振成像检查,患者诊断为急性大血管闭塞性后循环脑梗死。
    方法:患者在当地医院静脉输注阿加曲班(10mg)后症状未缓解。我们首先尝试通过正常方法打开闭塞的椎动脉,但失败了。然后我们刺穿了椎动脉,成功地打开了闭塞的椎动脉,并进行了机械血栓切除术。
    结果:患者成功进行椎动脉穿刺和机械取栓,没有证据表明穿刺部位有术后出血或血管损伤。患者在手术后第二天恢复了意识,但身体活动仍然受损。经过4个月的康复,病人完全康复了。
    结论:当常规方法不能满足机械血栓切除术的要求时,椎动脉反向穿刺是VASS患者可行的手术方法。然而,由于案件数量少,一系列安全问题,如潜在的穿刺失败,穿刺后出血,血管闭塞仍需进一步探讨。
    BACKGROUND: Vertebral artery stump syndrome (VASS) is a cause of acute stroke. Owing to the particularity of the pathogenesis of VASS, interventional treatment of VASS is difficult. Common mechanical thrombectomy approaches include femoral and radial artery approaches. However, conventional approaches may not be suitable for VASS. If effective measures are not taken to open offending vessels in time, this can lead to a high rate of disability. In recent years, no consensus has been reached regarding surgical methods for treating VASS.
    METHODS: The patient presented to the emergency department with a 2-hour history of disturbance of consciousness.
    METHODS: After neurological and magnetic resonance imaging examinations, the patient was diagnosed with acute large vessel occlusive posterior circulation cerebral infarction.
    METHODS: The patient\'s symptoms were not relieved after intravenous infusion of argatroban (10 mg) at a local hospital. We first attempted to open the occluded vertebral artery through normal approaches but failed. We then punctured the vertebral artery, successfully opened the occluded vertebral artery, and performed mechanical thrombectomy.
    RESULTS: The patient underwent successful vertebral artery puncture and mechanical thrombectomy, with no evidence of postoperative bleeding or vascular injury at the puncture site. The patient regained consciousness the day after surgery but remained impaired in physical activity. After 4 months of rehabilitation, the patient recovered completely.
    CONCLUSIONS: When the conventional approach cannot meet the requirements of mechanical thrombectomy, reverse puncture of the vertebral artery is a feasible surgical method for patients with VASS. However, due to the small number of cases, a series of safety problems such as potential puncture failure, hemorrhage after puncture, and vascular occlusion still need to be further explored.
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  • 文章类型: Case Reports
    背景:虽然中风和急性肢体缺血似乎很容易通过回忆和体格检查来区分,症状可能重叠,有时会误导检查者。这种情况可能发生在同时影响上肢和下肢的单侧神经症状的发生中。由于及时的诊断和正确的治疗干预对于防止这两种疾病的不可逆转的损害至关重要,了解一种疾病模仿另一种疾病的可能性是至关重要的。我们提出了一个模拟急性中风的急性单侧上肢和下肢缺血的独特病例。
    方法:一名已知动脉粥样硬化危险因素的69岁白种人患者因单侧感觉异常疑似卒中而进入急诊科。在对患者进行全面检查后,需要反复重新评估和脑部计算机断层扫描阴性,最终诊断为急性左侧上下肢缺血。患者行手术上下肢血运重建术,效果满意,数日后出院。
    结论:对模仿中风的人保持警觉至关重要,因为忽视会导致严重的并发症和延迟适当的治疗。我们的案例表明,即使在极少数情况下,持续的诊断努力也能成功治疗患者,急性单侧上下肢缺血也是如此。
    BACKGROUND: Although stroke and acute limb ischemia seem easily distinguishable by anamnesis and physical examination, symptoms may overlap and sometimes mislead the examiner. Such a situation can arise in the occurrence of unilateral neurological symptoms affecting the upper and lower limbs at the same time. As timely diagnosis and a correct therapeutic intervention are crucial to prevent irreversible damage in both diseases, knowledge of the possibility of one disease mimicking the other is essential. We present a unique case of acute unilateral upper and lower limb ischemia mimicking an acute stroke.
    METHODS: A 69-year-old Caucasian patient with known atherosclerotic risk factors was admitted to the emergency department with a suspected stroke with unilateral paresthesia. After a comprehensive examination of the patient with the need for repeated reevaluation and a negative brain computed tomography scan, acute left-sided upper and lower limb ischemia was eventually diagnosed. The patient underwent surgical revascularization of the upper and lower limbs with a satisfactory result and was discharged from the hospital after a few days.
    CONCLUSIONS: It is of utmost importance to always stay alert for stroke mimics, as overlooking can lead to severe complications and delay adequate therapy. Our case shows that persistent diagnostic effort leads to successful treatment of the patient even on rare occasions, as is the acute unilateral upper and lower limb ischemia.
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    文章类型: Case Reports
    一名72岁的男性患者表现为阻塞性黄疸,并被诊断为壶腹癌。对比增强计算机断层扫描(CT)显示肝总动脉狭窄和胰十二指肠拱廊(PDA)扩张由于腹腔轴狭窄(CAS)的起源,提示肝动脉血流通过PDA从肠系膜上动脉提供。由于在腹腔动脉(CA)的起点观察到动脉壁钙化,CAS的病因被诊断为动脉粥样硬化。术中胃十二指肠动脉(GDA)钳夹试验显示肝动脉血流量无明显减少。然而,由于对CA术后通畅的担忧,我们使用左大隐静脉行胰十二指肠下动脉-GDA旁路术,并进行胃部分保留胰十二指肠切除术.术后病程顺利。当动脉粥样硬化性CAS患者进行胰十二指肠切除术时,这种动脉重建方法可以考虑作为一种选择。
    A 72-year-old male patient presented with obstructive jaundice and was diagnosed with ampullary carcinoma. Contrast- enhanced computed tomography(CT)showed stenosis of the common hepatic artery and dilatation of the pancreaticoduodenal arcade(PDA)due to celiac axis stenosis(CAS)at the origin, suggesting that hepatic artery blood flow was supplied from the superior mesenteric artery via the PDA. Since calcification of the arterial wall was observed at the origin of the celiac artery(CA), the cause of the CAS was diagnosed as atherosclerotic. An intraoperative gastroduodenal artery(GDA) clamp test showed no obvious decrease in hepatic arterial blood flow. However, because of concerns about the postoperative patency of the CA, an inferior pancreaticoduodenal artery-GDA bypass using the left great saphenous vein and subtotal stomach-preserving pancreaticoduodenectomy were performed. The postoperative course was uneventful. When pancreaticoduodenectomy is performed in patients with atherosclerotic CAS, this arterial reconstruction method can be considered as an option.
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  • 文章类型: Case Reports
    一名60多岁的女性既往有缺血性中风史,出现了急性发作的言语含糊不清,左侧面部下垂和左侧无力,在接受二尖瓣和三尖瓣修复手术后多天,在CT血管造影中发现有闭塞性血栓。使用支架取出器和抽吸导管成功地清除了在组织学上被鉴定为“异物”的闭塞性材料。最终,患者表现出临床改善。异物栓塞是一种罕见但严重的并发症,可在二尖瓣和三尖瓣修复手术期间或之后发生。它可以引起缺血性中风,及时识别和立即干预是必要的,以防止严重的并发症。该病例报告强调了成功使用支架取出器介导的抽吸血栓切除术来清除患者的异物栓塞。它强调了及时干预以预防严重并发症的重要性,并显示了该技术的潜在益处。
    A woman in her 60s with a history of prior ischaemic stroke developed acute onset slurring of speech, left-sided facial droop and left-sided weakness and was found on CT angiography to have a subocclusive thrombus multiple days after undergoing mitral and tricuspid valve repair surgery. A stent retriever and aspiration catheter were used to successfully remove the subocclusive material which was identified as \'foreign material\' on histology. Ultimately, the patient demonstrated clinical improvement.Foreign material embolism is a rare but serious complication that can occur during or after mitral and tricuspid valve repair surgery. It can cause ischaemic stroke and prompt recognition and immediate intervention are necessary to prevent serious complications.The case report highlights the successful use of stent retriever-mediated suction thrombectomy to remove a foreign material embolism in a patient. It emphasises the importance of timely intervention to prevent serious complications and shows the potential benefits of this technique.
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  • 文章类型: Case Reports
    食管胃结合部癌的发病率一直在增加,导致人们对手术治疗的兴趣与日俱增。Leriche综合征,以局限于肾下主动脉的闭塞为特征,尚未报告与缺血性肠炎有关,以前没有关于该疾病的食管胃结合部癌的手术方法的报道。我们描述了一名五十多岁的男性患者,患有下腹痛和黑便,被诊断患有食管胃交界处癌,Leriche综合征,和缺血性肠炎.对比增强计算机断层扫描(CT)显示癌症出血,肾动脉分支以外的腹主动脉闭塞,直肠造影缺乏.三维(3D)-CT血管造影显示从腰动脉分叉到两个共同动脉的远端部分以及许多侧支途径的闭塞,说明直肠血液供应不稳定.基于3D-CT血管造影,在全身控制后,采用腹腔镜和胸腔镜对食管胃交界处癌进行了微创手术(MIS).患者出院,无术后并发症。伴有Leriche综合征的食管胃交界处癌可能因肿瘤出血和脆弱的侧支途径而并发缺血性肠炎。在3D-CT血管造影的引导下,使用腹腔镜和胸腔镜检查的MIS可以安全地进行这种疾病。
    The incidence of esophagogastric junction cancer has been increasing, leading to growing interest in surgical treatment. Leriche syndrome, characterized by occlusion limited to the infrarenal aorta, has not been reported to be associated with ischemic enteritis, and there are no previous reports on the surgical approaches for esophagogastric junction cancer in this disease.We describe the case of a male patient in his fifties with lower abdominal pain and melena who was diagnosed with esophagogastric junction cancer, Leriche syndrome, and ischemic enteritis. Contrast-enhanced computed tomography (CT) showed a hemorrhage from the cancer, occlusion of the abdominal aorta beyond the renal artery branches, and rectal contrast deficiency. Three-dimensional (3D)-CT angiography revealed occlusion from the lumbar artery bifurcation to the distal portions of both common iliac arteries plus numerous collateral pathways, indicating a precarious rectal blood supply. Based on 3D-CT angiography, minimally invasive surgery (MIS) using laparoscopy and thoracoscopy for esophagogastric junction cancer was performed after whole-body control. The patient was discharged without any postoperative complications.Esophagogastric junction cancer with Leriche syndrome can be complicated by ischemic enteritis due to tumor bleeding and fragile collateral pathways. MIS using laparoscopy and thoracoscopy guided by 3D-CT angiography can be safely performed for this disease.
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  • 文章类型: Case Reports
    目的:报告1例左眼视网膜分支动脉阻塞(BRAO)合并左侧先天性颈总动脉阻塞(CCAO)和颈内动脉阻塞(ICAO)。
    方法:病例报告。
    结果:一名36岁的男子仅出现左眼突然视力丧失,没有任何脑部疾病的体征或症状。荧光素眼底血管造影(FFA)显示左侧BRAO,头颈部计算机断层扫描血管造影(CTA)显示整个左侧CCAO和ICAO。患者左椎动脉经肌支与左枕动脉吻合,向左颈外动脉逆行供血。右颈内动脉通过前交通向左脑前动脉和大脑中动脉供血,左后交通动脉补偿左大脑中动脉的血液供应。
    结论:据我们所知,这项研究是第一个报告BRAO合并先天性CCAO和ICAO的病例,以视力下降为首发症状,并提出了头颈部检查在初次就诊时对视网膜动脉阻塞的重要性。
    OBJECTIVE: To report a case of branch retinal artery occlusion (BRAO) of the left eye combined with left congenital common carotid artery occlusion (CCAO) and internal carotid artery occlusion (ICAO).
    METHODS: Case report.
    RESULTS: A 36-year-old man presented with sudden vision loss of only the left eye without any signs or symptoms of brain diseases. Fluorescein fundus angiography (FFA) showed left BRAO, and computed tomography angiography (CTA) of the head and neck showed entire left CCAO and ICAO. The patient\'s left vertebral artery was anastomosed with the left occipital artery via the muscular branch, supplying blood retrogradely to the left external carotid artery. The right internal carotid artery compensated for blood supply to the left anterior cerebral artery and middle cerebral artery via anterior communication, and the left posterior communication artery compensated for blood supply to the left middle cerebral artery.
    CONCLUSIONS: To our knowledge, this study was the first to report a case of BRAO combined with congenital CCAO and ICAO with vision loss as the first symptom and proposed the importance of head and neck examination in retinal artery occlusion at the first visit to a doctor.
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  • 文章类型: Case Reports
    背景:突发性双侧耳聋通常与肿瘤等严重的系统性疾病有关,血管事件,自身免疫性疾病,感染,和医源性损伤,但很少到脑血管疾病。这是一例罕见的椎基底动脉闭塞患者的双侧突发性耳聋。
    方法:一名46岁的男子因突发性双侧耳聋被送往当地医院,6天后,患者言语不清,行走不稳定。
    方法:磁共振弥散成像显示脑桥和双侧小脑急性脑梗死;磁共振血管造影显示椎基底动脉闭塞。
    方法:阿司匹林和氯吡格雷用于抗血小板治疗,通过血管内治疗获得血运重建.
    结果:构音障碍的症状,共济失调和虚弱逐渐改善,入院后14天血运重建出院。经过3个月的电话随访,患者得到了自我护理。
    结论:耳聋有时可能是即将发生的椎基底动脉缺血性卒中的早期预警信号。早期认识到急性缺血性卒中的耳聋应进行特殊处理,和误诊可能导致显著的发病率,甚至死亡率。
    BACKGROUND: Sudden bilateral deafness is often associated with serious systematic conditions such as neoplasms, vascular events, autoimmune diseases, infections, and iatrogenic injury, but very rarely to cerebrovascular disease. This is a rare case of sudden bilateral deafness in a patient with the vertebrobasilar artery occlusion.
    METHODS: A 46-year-old man was admitted to a local hospital for sudden bilateral deafness, the patient suffered inarticulate speech and walking unsteadily 6 days later.
    METHODS: Difusion-weighted magnetic resonance imagin demonstrated acute cerebral infarction in the pons and bilateral cerebellum; Magnetic resonance angiography showed vertebrobasilar artery occlusion.
    METHODS: Aspirin and clopidogrel were given for antiplatelet therapy, revascularization was obtained by endovascular treatment.
    RESULTS: The symptoms of dysarthria, ataxia and weakness gradually improved and were discharged 14 days after admission revascularization. After 3 months telephone followed-up the patient was self-cared.
    CONCLUSIONS: Deafness sometimes can be an early warning sign of impending vertebrobasilar ischemic stroke. Early recognition of deafness with acute ischemic stroke should allow special management, and misdiagnosis may result in significant morbidity, or even mortality.
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  • 文章类型: Case Reports
    背景:主动脉动脉疾病是一种慢性进行性疾病,其特征是主动脉和髂动脉狭窄闭塞变化。治疗疾病晚期患者的金标准是主动脉双股重建术。主动脉周围钙化的患者具有术中并发症的高风险,由于难以在这样的区域交叉夹紧。
    方法:我们介绍了一例因左腿休息疼痛和第二脚趾溃疡入院的73岁患者。多层计算机断层扫描显示主动脉段明显狭窄,周围钙化的腹主动脉。使用通过左肱动脉放置的球囊导管,以主动脉腔内闭塞为特征,进行了主动脉重建。手术和术后过程都很顺利,患者在术后第六天出院。
    结论:所提出的混合血管内和开放手术技术是选择高危患者的有效替代方法。擦洗护士应熟悉血管内技术和工具,并了解防止电离辐射有害影响的措施。
    Aortoiliac arterial disease is a chronic progressive disease which is characterized by steno-occlusive changes in the aorta and iliac arteries. The gold standard for the treatment of patients with the advanced stage of the disease is aorto-bifemoral reconstruction. Patients with circumferential juxtarenal calcifications of the aorta bear a high risk of intraoperative complications, due to difficult cross-clamping in such zones.
    We present a case of a 73-year-old patient who has been admitted due to left leg rest pain and second toe ulceration. Multislice computed tomography showed significant stenosis of the aortoiliac segment with a circumferentially calcified abdominal aorta. Aortobifemoral reconstruction was performed featuring endoluminal occlusion of the aorta using a balloon catheter which was placed through the left brachial artery. The procedure and the postoperative course were uneventful, and the patient was discharged on the sixth postoperative day.
    The hybrid endovascular and open surgery technique presented emerged as a valid alternative for selected high-risk patients. Scrub nurses should be familiarized with endovascular techniques and tools and be aware of the measures to be protected from the harmful effects of ionizing radiation.
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