目的:血凝块的形成,通过根尖周出血或使用外周静脉血,富血小板血浆(PRP)或富血小板纤维蛋白(PRF),已广泛用于再生牙髓手术(REP)。除了诱导根尖周出血,从PRP获得的支架,PRF,和静脉血不是来自口腔颌面部组织。在这个案例报告中,从牙槽骨自体血凝块被描述,这涉及穿刺上颌末端牙槽骨。本病例报告的目的是评估成熟的恒前磨牙在再生牙髓手术中肺泡源性血凝块的疗效。
方法:一颗成熟的前磨牙有一个中央尖牙断裂,牙齿的发育像差之一,如果没有适当的治疗,导致慢性根尖周病变。为了解决这个问题,REP被雇用,利用通过上颌末端牙槽骨抽吸术获得的血液。
结果:29号牙齿的随访检查显示没有临床症状,根尖周病变区域的逐渐消退和根管管壁的增厚。
结论:该病例证明通过上颌末端牙槽骨穿刺获得的血凝块可成功应用于REP,并有可能处理根尖周病变。然而,需要进一步的临床试验来验证REP中肺泡源性血凝块的可行性,并将肺泡源性血凝块与目前使用的生物支架的结果进行比较.
结论:与来自外周静脉血的PRP或PRF相比,通过上颌末端牙槽骨穿刺术获得的血凝块可以由牙医施用,消除了对专业护士的依赖。在根尖周血液不足以覆盖根管的情况下,使用牙槽骨的血凝块可以简化REP。
OBJECTIVE: The formation of blood clot, achieved through periapical bleeding or the use of peripheral venous blood, platelet-rich plasma (PRP) or platelet-rich fibrin (PRF), has been widely utilized in regenerative endodontic procedures (REPs). Except for inducing periapical bleeding, the scaffolds obtained from PRP, PRF, and venous blood are not derived from oral and maxillofacial tissues. In this
case report, autologous blood clots from alveolar bone were described, which involved puncturing the maxillary terminal alveolar bone. The purpose of this
case report was to assess the efficacy of the alveolar-derived blood clot in regenerative endodontic procedures in a mature permanent premolar.
METHODS: A mature premolar had a fractured central cusp, one of the developmental aberrations of tooth, without a proper treatment, resulting in chronic periapical lesion. To address this condition, REPs were employed, utilizing blood obtained through aspiration from the maxillary terminal alveolar bone aspiration.
RESULTS: Follow-up examinations of tooth #29 revealed the absence of clinical symptoms, a progressive resolution of a periapical lesion area and thickening of the root canal walls.
CONCLUSIONS: This
case demonstrated that blood clot obtained through paracentesis of the maxillary terminal alveolar bone could be successfully applied in REPs and has potential to manage periapical lesions. However, further and more clinical trials are required to verify the feasibility of the alveolar-derived blood clot in REPs and compare the outcome of alveolar-derived blood clot with currently used biological scaffolds.
CONCLUSIONS: In comparison to PRP or PRF from peripheral venous blood, blood clots obtained via paracentesis of the maxillary terminal alveolar bone could be administrated by dentists, eliminating the need for reliance on professional nurses. The use of blood clots from alveolar bone could simplify the REPs in cases where periapical blood was insufficient to brim the root canals.