目的:评估妊娠对前房的影响,角膜参数,和眼内压测量;并比较三个月之间的结果,产后和未怀孕的健康年龄匹配的妇女。
方法:这项前瞻性研究包括41名孕妇和53名非孕妇。对孕妇进行了四次测量,在每三个月和产后第三个月,一次来自对照组。在研究中包括的个人中,前房深度(ACD),前房容积(ACV),K1(平面角膜曲率测量),K2(陡峭角膜曲率测量),Kmean(K1和K2的平均值),前房角(ACA),中央角膜厚度(CCT),最薄角膜厚度(TCT),散光值(AST),角膜体积(CV),生物测量,轴向长度(AL),球面当量(SFEQ),人工晶状体屈光力(ILP),记录VA(视敏度)数据。
结果:我们观察到K2,CCT,ACD,产后期AL和CV(分别为p=0.025,p<0.001,p=0.029,p=0.005,p=0.004),ACV有统计学意义的增加,CCT,和TCT在妊娠组中随着孕周的进展而进展(分别为p=0.007,p<0.001,p=0.025)。到妊娠晚期,IOP有统计学意义的下降,产后时间增加(p<0.001)。我们没有观察到K1、Kmean、AST,ACA,VA,ILP,和SFEQ值。
结论:调查怀孕期间可能发生的生理变化很重要,将它们与病理变化区分开来,避免不必要的治疗。我们认为,指导白内障和屈光手术等眼前节手术的时机以及处方眼镜/隐形眼镜也很重要。
OBJECTIVE: To evaluate the effect of pregnancy on the anterior chamber, corneal parameter, and intraocular pressure measurements; and compare the results between trimesters, postpartum and non-pregnant healthy age-matched women.
METHODS: This prospective
study included 41 pregnant women and 53 non-pregnant women. Four measurements were taken from the pregnant women, in each trimester and postpartum third month, and once from the control group. Of the individuals included in the
study, anterior chamber depth (ACD), anterior chamber volume (ACV), K1 (flat keratometry), K2 (steep keratometry), Kmean (mean value of K1 and K2), anterior chamber angle (ACA), central corneal thickness (CCT), thinnest corneal thickness (TCT), astigmatism value (AST), corneal volume (CV), biometry, axial length (AL), spherical equivalent (SFEQ), intraocular lens power (ILP), VA (visual acuity) datas were recorded.
RESULTS: We observed a statistically significant decrease in K2, CCT, ACD, AL and CV in the postpartum period (p = 0.025, p < 0.001, p = 0.029, p = 0.005, p = 0.004 respectively) and a statistically significant increase in ACV, CCT, and TCT as the gestational week progressed in the pregnant group (p = 0.007, p < 0.001, p = 0.025, respectively). A statistically significant decrease in IOP towards to the third trimester, and an increase in the postpartum period was observed (p < 0.001). We did not observe statistically significant changes in K1, Kmean, AST, ACA, VA, ILP, and SFEQ values.
CONCLUSIONS: It is important to investigate the physiological changes that may occur during pregnancy, distinguish them from pathological changes, and avoid unnecessary treatment. We consider that it\'s also important to guide the timing of anterior segment surgeries such as cataract and refractive surgery and to prescribe glasses/contact lenses.