目的从临床改善和症状缓解两方面,比较和研究tar修补术和羊膜移植治疗持续性角膜上皮缺损的临床效果。
这是一个介入,前瞻性研究共60例持续性上皮缺损(PED)患者,随机分为两组,每组30例,分别接受了tarsorraphy(A组)或羊膜移植(B组),随访4周,包括在内。研究的主要参数是上皮缺损的大小,总愈合时间,疼痛评分,和并发症。
该研究包括60例PED患者的60只眼。A组愈合时间为9.83±6.51天(中位数=9.50天,IQR=1-7天)与18.33±13.46天(中位数=19.50天,B组的IQR=1-21天)。在4周结束时,共有十只眼睛(16.7%)没有愈合。
术后1周和2周随访结束时,上皮缺损面积显著减少,在两种治疗形式中。A组患者的平均愈合时间比B组患者的平均愈合时间短。
To compare and
study the clinical outcome of tarsorrhaphy and amniotic membrane transplant in the healing of persistent corneal epithelial defects in terms of clinical improvement and symptomatic relief.
This was an interventional, prospective
study in which a total of 60 patients with persistent epithelial defects (PED\'s), randomly divided into two groups of 30 patients each who underwent tarsorrhaphy (Group A) or amniotic membrane transplantation (Group B) with a 4-week-follow-up period, were included. The main parameters studied were the size of an epithelial defect, total healing time, pain score, and complications.
The
study included 60 eyes of 60 patients with PED. The healing time was 9.83 ± 6.51 days in Group A (median = 9.50 days, IQR = 1-7 days) vs. 18.33 ± 13.46 days (median = 19.50 days, IQR = 1-21 days) in Group B. A total of ten eyes (16.7%) did not heal at the end of 4 weeks.
There was a significant reduction in the area of epithelial defect at the end of the 1 week and 2 week follow up postoperatively, in both the treatment forms. The mean healing time in patients of Group A was less as compared to that of the patients in Group B.