■达克气单胞菌是革兰氏阴性细菌。近年来,达克气单胞菌由于其毒力强、预后差,逐渐引起人们的重视。由达克气单胞菌引起的肺部感染的临床报道很少。
■一名急性T淋巴细胞白血病患者化疗后出现骨髓抑制,达克气单胞菌继发肺部感染,因发烧住院。患者接受了炎症标志物检测,胸部成像,血培养,支气管肺泡灌洗,胸膜引流,并对肺泡灌洗液和胸膜液进行宏基因组下一代测序,以获得达克气单胞菌感染的证据,用四代头孢菌素联合氟喹诺酮类抗生素治疗。患者病情明显改善。
■在肺部感染病原体中,达克气单胞菌相对罕见。一旦在临床工作中培养了气单胞菌菌株,应对检出的样本进行病原测序,以便早期准确诊断和有效的抗感染治疗。
UNASSIGNED: Aeromonas dhakensis is a gram-negative bacterium. In recent years, Aeromonas dhakensis has gradually attracted increasing attention due to its strong virulence and poor prognosis. Clinical
reports of pulmonary infection caused by Aeromonas dhakensis are rare.
UNASSIGNED: A patient with acute T lymphoblastic leukemia experienced myelosuppression after chemotherapy, developed a secondary pulmonary infection with Aeromonas dhakensis and was hospitalized due to fever. The patient underwent testing for inflammatory markers, chest imaging, blood culture, bronchoalveolar lavage, pleural drainage, and metagenomic next-generation sequencing of alveolar lavage fluid and pleural fluid to obtain evidence of Aeromonas dhakensis infection, and was treated with four generations of cephalosporin combined with fluoroquinolone antibiotics. The patient\'s condition significantly improved.
UNASSIGNED: Among pulmonary infectious pathogens, Aeromonas dhakensis is relatively rare. Once an Aeromonas strain is cultured in the clinical work, pathogenic sequencing should be performed on the detected samples for early accurate diagnosis and effective anti-infection treatment.