Adolescent Psychiatry

青少年精神病学
  • 文章类型: Journal Article
    儿科行为和心理健康(BMH)障碍越来越普遍,但是大多数儿科医生觉得没有足够的训练来管理它们。我们实施了基于案例的,BMH儿科住院医师计划中的纵向课程,以准备学员诊断和管理这些疾病。
    莱特州立大学/赖特-帕特森医学中心的儿科住院医师计划在2020-2021年实施了新的BMH课程。课程包括五个涉及抑郁症的模拟案例,焦虑,多动注意力缺陷障碍(ADHD),发育迟缓,行为关注,和自闭症。为了反映连续性诊所内的随访情况,病例包括初次接触和多次随访.在整个学年中,教师主持人带领居民参加每月的小组会议,每个会话包括两到三个模拟患者的遭遇。居民完成了关于他们对诊断和管理BMH状况的信心以及前测和后测的调查,以评估课程对知识收益的影响。
    所有47名儿科居民都参加了课程;38名(81%)完成了事后调查。课程完成后,居民报告说,管理多动症的信心显着增加,治疗抑郁症,为自杀制定安全计划,认识到自闭症,并就特殊教育服务为患者和家庭提供咨询。由25名居民(53%)完成的基于知识的前后测试也显示出显着改善(M=92.4,SD=10.9,prevs.M=99.3,SD=6.6,后,p=.009)。
    基于此案例,儿科BMH的纵向课程模拟患者连续性,提高了住院医师诊断和管理常见BMH疾病的信心和知识.
    UNASSIGNED: Pediatric behavioral and mental health (BMH) disorders are increasingly common, but most pediatricians feel inadequately trained to manage them. We implemented a case-based, longitudinal curriculum in BMH within a pediatric residency program to prepare trainees to diagnose and manage these conditions.
    UNASSIGNED: The pediatric residency program at Wright State University/Wright-Patterson Medical Center implemented a new BMH curriculum in 2020-2021. The curriculum consisted of five simulated cases involving depression, anxiety, attention deficit disorder with hyperactivity (ADHD), developmental delays, behavioral concerns, and autism. To reflect follow-up within a continuity clinic, cases included initial encounters and multiple follow-up visits. Faculty facilitators led residents in monthly small-group meetings over the academic year, with each session consisting of two to three simulated patient encounters. Residents completed pre-post surveys regarding their confidence in diagnosing and managing BMH conditions and pre- and posttests to evaluate the impact of the curriculum on knowledge gains.
    UNASSIGNED: All 47 pediatric residents participated in the curriculum; 38 (81%) completed pre-post surveys. Upon completion of the curriculum, residents reported significantly increased confidence in managing ADHD, treating depression, creating safety plans for suicidality, recognizing autism, and counseling patients and families on special education services. Knowledge-based pre- and posttests completed by 25 residents (53%) also demonstrated significant improvement (M = 92.4, SD = 10.9, pre vs. M = 99.3, SD = 6.6, post, p = .009).
    UNASSIGNED: This case-based, longitudinal curriculum in pediatric BMH simulating patient continuity improved residents\' confidence and knowledge in diagnosing and managing common BMH conditions.
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  • 文章类型: Journal Article
    此案例比较说明了与ABCB1基因相关的精神和临床管理中的药物遗传学测试,其编码影响血脑屏障(BBB)通透性的P-糖蛋白转运体。两名儿科患者(9岁和11岁)被选择为具有相反ABCB1基因型的相似临床表现,而关键CYP450,多巴胺能和5-羟色胺能基因(CYP2C9,CYP2C19,DRD2,SLC6A4,5HTR2A)相同。病例A具有ABCB1基因的功能(G/Grs1045642),提示BBB具有功能性P-糖蛋白转运蛋白。病例B是ABCB1基因的亚功能(A/Ars1045642),提示患者的血脑屏障可能对精神药物具有渗透性。病例A比病例B有更多的药物试验和剂量调整。病例A有两次住院和穿插急诊室就诊。而病例B没有。
    本病例比较报告的重点是ABCB1基因在儿童精神病学中的作用及其在药物疗效和副作用中的作用。ABCB1编码血脑屏障(BBB)的P-糖蛋白转运蛋白。因为抗抑郁药必须穿过血脑屏障才能作用于大脑,ABCB1功能的差异可能导致不同的抗抑郁药的脑浓度和随后的治疗反应的差异.选择病例与ABCB1基因的相反功能进行比较,同时匹配关键CYP450,多巴胺能和5-羟色胺能基因(CYP2C9,CYP2C19,DRD2,SLC6A4,5HTR2A),是使用的方法。病例A和病例B的结果反映了药物遗传学和临床对照,包括患者对抗抑郁药和抗精神病药的反应,对不良反应的易感性和症状严重程度的差异。这些对抗抑郁药和抗精神病药的影响很重要,因为渗透性BBB将允许这些药物进入大脑发挥其作用,从而改善临床结果,减少住院和急诊室就诊,并尽量减少药物试验和剂量变化。需要更多的临床关注和研究BBB参与精神疾病和P-糖蛋白转运蛋白作为大脑的化学看门人。可以考虑对ABCB1多态性进行药物遗传学测试,以在不久的将来为儿童和青少年精神病学中最脆弱的患者提供精神处方。
    This case comparison illustrates pharmacogenetic testing in psychotropic and clinical management in relation to the ABCB1 gene, which encodes the P-glycoprotein transporter affecting blood-brain barrier (BBB) permeability. Two pediatric patients (9 and 11 years old) were selected for similar clinical presentations with opposing ABCB1 genotype, while they were identically matched for key CYP450, dopaminergic and serotonergic genes (CYP2C9, CYP2C19, DRD2, SLC6A4, 5HTR2A). Case A was functional for the ABCB1 gene (G/G rs1045642), suggesting that the BBB had a functional P-glycoprotein transporter. Case B was subfunctional for the ABCB1 gene (A/A rs1045642), suggesting that the patient\'s BBB may be permeable to psychotropic drugs. Case A had more medication trials and dose adjustments than Case B. Case A had two inpatient admissions and interspersed emergency room visits, while case B had none.
    The focus of this case comparison report is the ABCB1 gene in child psychiatry and its role in drug efficacy and side effects. ABCB1 encodes the P-glycoprotein transporter of the blood–brain barrier (BBB). As antidepressants must cross the BBB to act on the brain, differences in the functionality of ABCB1 may lead to variable brain concentrations of antidepressants and subsequent variability in therapeutic response. Selecting the cases for comparison with opposing functionality at the ABCB1 gene, while matching for key CYP450, dopaminergic and serotonergic genes (CYP2C9, CYP2C19, DRD2, SLC6A4, 5HTR2A), was the approach utilized. The outcomes of case A and case B reflected pharmacogenetic and clinical contrasts, including patient responses to antidepressants and antipsychotics, susceptibility to adverse effects and differences in the severity of symptoms. These effects on antidepressants and antipsychotics are important because a permeable BBB will allow these drugs to cross into the brain to exert their effect, thus improving clinical outcomes, reducing hospitalizations and emergency room visits and minimizing drug trials and dosage changes. More clinical attention and research are needed for the BBB\'s involvement in psychiatric disease and for the P-glycoprotein transporter as a chemical gatekeeper to the brain. Pharmacogenetic testing for ABCB1 polymorphisms could be considered to inform psychotropic prescribing for the most vulnerable patients in child and adolescent psychiatry in the near future.
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  • 文章类型: Journal Article
    对当前文献的回顾证明了皮肤状况的心理含义。不同严重程度的皮肤状况会影响患者的生活质量并产生精神病后果。这种影响使医疗保健提供者需要考虑皮肤状况的心理影响及其对生活质量的影响。由不同的皮肤状况引起的心理挑战表明了对皮肤病学和精神病学干预的潜在需求。以下文献综述详述了各种条件下皮肤状况的精神病后果。它首先着眼于强调不同年龄段经历的精神病学后果的文献,从成人到青少年和儿童。然后,本文探讨了多种皮肤状况及其心理影响,然后强调了压力对皮肤的一些相互作用,这些相互作用可能会进一步加剧一个人的状况。最后,它检查了患者如何表征他们的皮肤状况,并进入一些临床案例研究的患者的心理影响,因为他们的皮肤疾病。该论文还强调了皮肤病患者的心理状况及其皮肤状况。
    This review of current literature demonstrates the psychological implications of skin conditions. Skin conditions of varying severity can impact the quality of patients\' lives and have psychiatric consequences. This impact provides a need for healthcare providers to consider the psychological implications of one\'s skin conditions and their effect on quality of life. The psychological challenges that arise from varying skin conditions show the potential need for both dermatological and psychiatric interventions. The following literature review details the psychiatric consequences of skin conditions under various conditions. It first looks at literature highlighting the psychiatric consequences experienced through various age ranges, from adults to adolescents and children. The paper then explores multiple skin conditions and their psychological effect before highlighting some of the interactions that stress has on the skin that could further exacerbate one\'s condition. Finally, it examines how patients characterize their experience with their skin condition and goes into some clinical case studies of patients with psychological implications as a result of their skin disorder. The paper also highlights the magnitude of dermatologic patients experiencing psychological conditions in conjunction with their skin conditions.
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  • 文章类型: Case Reports
    尽管兄弟姐妹性虐待(SSA)可能是最常见的家族内性虐待类型,它还没有被广泛研究。缺乏研究使得临床医生很难建立一个关于这种复杂现象的全面框架,特别是与其他形式的家庭内性虐待相比,比如父女乱伦。SSA仍然未得到充分认可和披露,但它有可能与父母的性虐待一样有害。该主题很少进入更一般的精神病学或社会工作文献。必须提高医疗保健从业人员对这一复杂主题的认识,以提高他们的倾听能力,检测,并管理青少年人群中SSA的披露。本文介绍了三名13至15岁的青春期女孩的小插曲,这些女孩在青春期精神科和医学部住院期间披露了SSA。这些案例说明了SSA的复杂性,这与各种各样的精神和身体症状有关。SSA的青少年受害者经历了严重的痛苦,有各种各样的精神表现,包括但不限于抑郁和自杀未遂,上瘾的行为,创伤后应激症状,和饮食失调。身体症状也应该提醒从业者:青少年幸存者更容易受到性传播疾病等躯体并发症的影响,慢性疼痛,泌尿生殖器症状,和营养失调。我们提供了一些建议,以改善对患有SSA的青少年的发现和支持。倾听它们并提供保护性的多学科反应可以限制持久的损害并有助于修复过程。
    Although sibling sexual abuse (SSA) may be the most common type of intrafamilial sexual abuse, it has not been widely studied. The lack of studies makes it very difficult for clinicians to create a comprehensive framework about this complex phenomenon, particularly in comparison with other forms of intrafamilial sexual abuse, such as father-daughter incest. SSA is still underrecognized and underdisclosed but it has the potential to be every bit as harmful as sexual abuse by a parent. The topic rarely finds its way into the more general psychiatry or social work literature. It is imperative to increase healthcare practitioners\' awareness of this complex subject to improve their ability to listen to, detect, and manage the disclosures of SSA in adolescent populations. This paper presents vignettes of three 13-to-15-year-old adolescent girls who disclosed SSA during inpatient hospitalization in an adolescent psychiatric and medicine department. These cases illustrate the complexity of SSA, which has been associated with a wide spectrum of both mental and physical symptoms. Adolescent victims of SSA experience serious distress, with various and numerous psychiatric manifestations, including but not limited to depression and suicide attempts, addictive behaviors, post-traumatic stress symptoms, and eating disorders. Physical symptoms should also alert practitioners: adolescent survivors are more likely to be affected by somatic complications such as sexually transmitted diseases, chronic pain, urogenital symptoms, and nutritional disorders. We offer some recommendations to improve the detection and support of distressed adolescents disclosing SSA. Listening to them and offering a protective multidisciplinary response can limit the lasting damage and contribute to the repair process.
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  • 文章类型: Case Reports
    The COVID-19 has emerged as a public health emergency across the globe. Countries all over the world have been forced to enforce nationwide lockdowns to curb the transmission of this illness, affecting millions of people. The disorder and the lockdowns enforced have resulted in a complex set of psychosocial stressors in the lives of people, affecting their resilience and causing psychological stress and mental health issues. In this case series, we aim to highlight the role of such psychosocial stressors in causing mental health problems, especially in a vulnerable individual. The first case reports the onset of first-episode mania in a healthy individual with a family history of mental illness, after the sudden demise of the patient\'s mother due to COVID-19. The second case highlights the onset of psychosis in an adolescent girl following academic stress due to the inability to carry on her education through online classes. The third case demonstrates the exacerbation of dissociative episodes in a child following the financial crisis in the family during the lockdown period. In low-income to middle-income countries such as India, there is a complex interplay of the psychosocial stressors due to the COVID-19 pandemic with pre-existing issues such as poverty, socioeconomic disparity and inequity of resources leading to a \'double hit\' for people from disadvantaged sections of the society and individuals with pre-existing mental illness or vulnerability for mental illness.
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  • 文章类型: Case Reports
    Catatonia是一种精神运动综合征,具有特定的言语簇,行为和运动特征。尽管可能危及生命,尤其是其恶性形式伴有自主神经失调和医学并发症,这是一种可以治疗的疾病,当及时识别。长期以来,紧张症被认为是精神分裂症的标志,从而限制了诊断和治疗的可能性。由于对该主题的认识和研究的提高,现在已经知道,卡通症可以发生在许多疾病的背景下,包括精神病患者,情感和神经发育障碍。近年来,人们对神经发育障碍中卡通症的识别和定义重新产生了兴趣,如自闭症谱系障碍(ASD),鉴别诊断带来了巨大的挑战,考虑到症状和体征之间存在相当大的重叠。我们介绍了一个15岁的高功能ASD男孩,突然出现严重的紧张性症状,并伴有精神病症状,其复杂的临床过程对所述疾病的分化和关系提出了许多问题。
    Catatonia is a psychomotor syndrome with specific clusters of speech, behavioral and motor features. Although potentially life-threatening, especially in its malignant form accompanied with autonomic dysregulation and medical complications, it is a treatable condition, when promptly identified. For a long time catatonia was considered a marker of schizophrenia, thus limiting the possibility of diagnosis and treatment. Due to growing awareness and studies on the subject, it is now known that catatonia can occur in the context of a number of diseases, including psychotic, affective and neurodevelopmental disorders. In recent years, there\'s been a renewed interest in the recognition and definition of catatonia in neurodevelopmental disorders, such as Autism Spectrum Disorder (ASD), where the differential diagnosis poses great challenges, given the considerable overlapping of signs and symptoms between the conditions. We present the case of a 15 year old boy with High Functioning ASD with a sudden onset of severe catatonic symptoms and the co-existence of psychotic symptoms, whose complex clinical course raises many questions on the differentiation and relation of said disorders.
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  • 文章类型: Case Reports
    In this paper, we outline our approach to dealing with complex social isolation by presenting a network treatment approach named Adaptive Mentalization-Based Integrative Treatment (AMBIT).
    We describe the AMBIT approach, what elements it consists of, and we explain how we employed this method in the case of a 17-year-old boy referred to our child and adolescent psychiatric clinic, who isolated himself from the world.
    We emphasize in which ways the specific network approach pertinent to the AMBIT approach was helpful in this complex case. Furthermore, we describe and reveal our insecurities and doubts related to our interventions and the general treatment process and point to why the AMBIT network approach and the interventions were crucial in this case.
    We argue that the boy could not have been helped out of his social isolation within the conventional child and adolescent psychiatric system without engaging and establishing an integrated professional network from many sectors.
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  • 文章类型: Case Reports
    适应不良的白日梦(MD)是一种身临其境的幻想活动,会导致痛苦和社会职业功能障碍。MD有许多暗示行为成瘾的特征,但是探索这种临床结构现象学的研究是有限的。MD也被认为是一种应对困境的不适应策略,但经常导致幻想世界中无法控制的吸收,社会退缩和日常生活中被忽视的方面。在本文中,我们报告了一个16岁男孩的案例,他在经历了同龄人的网络欺凌后患上了网络游戏障碍和MD。病人从事生动,持续数小时的幻想图像,导致社会功能障碍和学业恶化。基线评估显示,适应不良的白日梦量表16得分为65(截止值50),互联网游戏测试20得分为86(截止值71)。患者主要接受心理干预。该疗法侧重于行为矫正和认知重构。当过度使用技术或其他形式的行为成瘾时,应向临床环境中的患者询问MD。需要进一步的研究来确定MD的生物心理社会因素及其相关因素。还需要研究用于治疗MD的治疗和管理方法。
    Maladaptive daydreaming (MD) is an immersive fantasy activity that leads to distress and socio-occupational dysfunction. MD has many features suggestive of behavioural addiction, but research exploring the phenomenology of this clinical construct is limited. MD has also been purported to be a maladaptive strategy to cope with distress, but often leads to uncontrollable absorption in fantasy world, social withdrawal and neglected aspects of everyday life. In this paper, we report the case of a 16-year-old boy who developed internet gaming disorder and MD after experiencing cyberbullying from his peers. The patient engaged in vivid, fanciful imagery that lasted for hours, leading to social dysfunction and academic deterioration. Baseline assessment revealed a Maladaptive Daydreaming Scale-16 score of 65 (cut-off 50) and an Internet Gaming Test-20 score of 86 (cut-off 71). The patient was managed primarily with psychological intervention. The therapy focused on behaviour modification and cognitive restructuring. Patients in clinical setting should be questioned about MD when presenting with excessive use of technology or other forms of behavioural addictions. Further studies are necessary to determine the biopsychosocial factors of MD and its correlates. There is also a need to study treatment and management approaches for treating MD.
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  • 文章类型: Journal Article
    Based on the specific experience of a tertiary university hospital in Paris, France, we propose a theoretical framework encompassing developmental, multidimensional, eco-systemic, and multifactorial perspectives for child and adolescent psychiatry. Consequently, a modern CAPD should be multidisciplinary and implemented in a large medical setting with close disciplines, should promote tailored and integrative treatment, should include some organizational aspects (e.g., tutoring), and should also be opened to cultural and school interventions. Finally, for complex cases, it should keep ambitious goals in terms of both clinical and functional recovery.
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  • 文章类型: Journal Article
    Objectives: In undergraduate medical education and in the subject of child and adolescent psychiatry, examining young patients face-to-face is a key element of teaching. With the abrupt shutdown of face-to-face teaching caused by the SARS-CoV-2 pandemic, a case-based online training program integrating audio and video of real patients was developed. Methods: The blended learning platform CaseTrain guides medical students in their final year through real child-psychiatric patient cases, such as anorexia, autism, or attention deficit disorder, through presentation of video and audio of real patients and parents. The teaching format complements lectures on child psychiatric topics, comprising asynchronous elements (self-study using the digital material) as well as synchronous elements (web-conferences with a specialist). Learning objectives for students were set to develop knowledge of the spectra of psychiatric disorders that affect children and to recognize approaches how to assess and manage common psychiatric problems of childhood and adolescence. Results: The feedback from medical students through oral and written evaluation was positive. They appreciated getting to know \'real-world patients\' in times of such a pandemic, to learn explorative techniques from role models, and to be in close contact with the supervising specialist. In consequence of critical feedback on the length of some video sequences, these training units will undergo revision. Conclusions: Case-based online training may continue to be a useful option in a post-pandemic future as integral part of medical education, complementing face-to-face lectures and training in (child) psychiatry.
    Zielsetzungen: Im Studium der Humanmedizin und besonders im Fach Kinder- und Jugendpsychiatrie ist die Untersuchung junger Patienten von Angesicht zu Angesicht ein Schlüsselelement der Lehre. Mit der abrupten Einstellung der Präsenzlehre aufgrund der SARS-CoV-2-Pandemie wurde ein fallbasiertes Online-Trainingsprogramm entwickelt, in das Audio- und Videoaufnahmen von realen Patienten integriert wurden.Methoden: Auf der Plattform CaseTrain, eingebettet in ein Blended-Learning-Konzept, bearbeiten Medizinstudierende kinderpsychiatrische Patientenfälle, beispielsweise zu den Themen Anorexie, Autismus oder Aktivitäts- und Aufmerksamkeitsstörung. Videos und Audioaufnahmen realer Patientinnen und Patienten und deren Eltern sind in die Fälle integriert. Das Online-Lehrangebot für Studierende im letzten Studienjahr vor dem Praktischen Jahr wird ergänzt durch Vorlesungen zu kinderpsychiatrischen Themen und enthält sowohl asynchrone (Selbststudium unter Verwendung des digitalen Materials) als auch synchrone Elemente (Web-Konferenzen mit einer fachärztlichen Person oder erfahrenen Psychologinnen und Psychologen). Die Lerninhalte umfassen das gesamte Spektrum psychischer Störungen im Kindes- und Jugendalter. Ferner werden Kompetenzen zu häufigen psychischen Problemen im Kindes- und Jugendalter im Hinblick auf die klinische Einordnung und zielgerichteter diagnostischer und therapeutischer Verfahren vermittelt.Ergebnisse: Das Feedback durch die Medizinstudierenden mittels mündlicher und schriftlicher Evaluationen war positiv. Sie schätzten es, in Pandemie-Zeiten den \"Patienten aus der realen Welt\" virtuell zu begegnen, Gesprächsmethoden am Vorbild zu erlernen und sich mit den Lehrpersonen auszutauschen. Infolge der kritischen Rückmeldung zur Länge einiger Videosequenzen werden diese Ausbildungseinheiten überarbeitet.Schlussfolgerungen: Das hier vorgestellte fallbasierte Online-Trainingsprogramm kann auch in Zukunft nach der Pandemie ein wertvolles Lehrangebot darstellen und Präsenzveranstaltungen in der (Kinder- und Jugend-)Psychiatrie – wie Vorlesungen und Praktika – im Sinne eines integrierten Ausbildungsansatzes ergänzen.
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