背景:由于其闭塞和可压缩特性,泡沫胶带通常在急诊科用作胸管上的敷料。关于对这种材料的显著皮肤反应的发生率的数据很少。我们进行了一项前瞻性试验,以评估将泡沫胶带应用于健康志愿者的上臂后皮炎的发生率。
方法:这是一个前瞻性的,介入试验。我们招募了一群同意的人,健康的医生,护士,以及对泡沫胶带不敏感的教学设施的辅助人员。研究人员将2×2英寸的3M微泡沫粘合剂施加到每个受试者上臂的内侧。对侧臂作为比较的参考。粘合剂保持48小时,研究作者使用先前验证的皮肤刺激评分系统(CISS)评估患者。用卡方分析分类变量,采用t检验的连续变量。
结果:研究组有40名受试者,52%为女性,平均年龄40±7岁,55%的非白人种族。10/40(25%;95CI[14%,41%])的受试者有红斑;9/40(22%)的红斑评分为1,1/40(2.5%)的评分为2。关于水肿,2/40(5%;95%CI[1%,18%]);1/40(2.5%)的水肿评分为1,1/40(2.5%)的评分为2。有9/40的受试者的刺激性评分>0;(22%;95CI[12%,38%]);7/40(18%)的刺激性评分为1,2/4(5.0%)的评分为2。就严重性评分而言,10/40(25%;95CI[14%,41%])得分为>0分;9/40(22%)得分为1分,1/40(2.5%)得分为2分。总的来说,10/40(25%;95CI[14%,41%])的受试者至少有一种积极的反应。受试者\'年龄,性别和种族没有发现与红斑的发生率有统计学意义的相关,水肿,或者烦躁。此外,这些特征与严重程度评分>0无统计学意义.所有上述双变量分析的p值均>0.05。
结论:25%的健康志愿者在手臂上使用泡沫胶带后发生皮肤反应。患者特征与皮肤反应的风险无关。
背景:#NCT06059417。
Foam tape is commonly used in the emergency department as a dressing over chest tubes owing to its occlusive and compressible properties. There is a paucity of data regarding the incidence of significant cutaneous reactions to this material. We conducted a prospective
trial to evaluate the incidence of dermatitis following application of foam tape to the upper arm of a cohort of healthy volunteers.
This was a prospective, interventional
trial. We enrolled a cohort of consenting, healthy physicians, nurses, and ancillary staff at a teaching facility who did not have known hypersensitivity to foam tape.
Study investigators applied a 2 × 2 inch piece of 3 M microfoam adhesive to the medial aspect of each subject\'s upper arm. The contralateral arm served as a reference for comparison. The adhesive remained in place for 48 h and the
study authors assessed patients utilizing the previously validated Cutaneous Irritancy Scoring System (CISS). Categorical variables analyzed by chi-square, continuous variables with t-tests.
There were 40 subjects in the
study group; 52% female, mean age 40±7 years, 55% non-White race. 10/40 (25%; 95%CI[14%, 41%]) of subjects had erythema; 9/40 (22%) had an erythema score of 1 and 1/40 (2.5%) had a score of 2. With respect to edema, 2/40 (5%; 95% CI[1%,18%]); 1/40(2.5%) had an edema score of 1, and 1/40(2.5%) had a score of 2. There were 9/40 subjects with an irritancy score > 0; (22%; 95%CI[12%,38%]); 7/40(18%) had an irritancy score of 1, and 2/4(5.0%) had a score of 2. In terms of the severity score, 10/40 (25%; 95%CI[14%, 41%]) had a score > 0; 9/40(22%) had a score of 1, and 1/40(2.5%) had a score of 2. Overall, 10/40 (25%; 95%CI[14%, 41%]) of subjects had at least one positive measure of a reaction of any kind. Subjects\' age, gender and race were not found to be statistically significantly associated with the incidence of erythema, edema, or irritancy. In addition, these characteristics were not statistically significantly associated with severity score > 0. The p values for all the above bivariate analyses were > 0.05.
Cutaneous reactions occurred in 25% of healthy volunteers after the application of foam tape to the arm. Patient characteristics were not associated with risk of a skin reaction.
#NCT06059417.