PDF(Sci-hub)
Abstract：
Clinical diagnosis of STDs is unreliable and therefore constitutes a poor basis for choice of treatment. A syndromic approach has been suggested to increase effectiveness of treatment in resource poor settings. Algorithms for the treatment of STD syndromes were evaluated. A total of 436 patients were followed; cure rates were defined and estimated for genital ulcer disease (GUD), urethral and vaginal discharge. Cure rates for the discharge syndromes were high, 97-98%, for both sexes. The cure rate for GUD was 83% for female and 69% for male patients. A higher prevalence of syphilis in the female study population probably contributed to this. It is likely that a large proportion of the treatment failures were due to decreased susceptibility of Haemophilus ducreyi to trimethoprim-sulpha. The determination of cure rates met with a number of methodological problems. This makes it difficult to evaluate the algorithms as part of routine activities, as suggested earlier by WHO.
摘要：
性病的临床诊断是不可靠的，因此构成了选择治疗的不良基础。已经提出了一种综合方法来提高资源匮乏地区的治疗效果。评估了治疗STD综合征的算法。共随访了436例患者；确定并估计了生殖器溃疡（GUD）的治愈率，尿道和阴道分泌物。出院综合征的治愈率很高，97-98%,对两性。女性患者的GUD治愈率为83％，男性患者为69％。女性研究人群中梅毒的患病率较高可能是造成这种情况的原因。治疗失败的很大一部分可能是由于杜氏嗜血杆菌对甲氧苄啶-磺胺的敏感性降低。治愈率的确定遇到了许多方法学问题。这使得很难将算法作为日常活动的一部分进行评估，正如世卫组织早些时候提出的那样。
