关键词: Nodular fasciitis case report diagnostic challenge fibroblast non-neoplastic hyperplasia vocal cords

Mesh : Humans Male Fasciitis / diagnosis surgery pathology Aged Vocal Cords / pathology surgery Hoarseness / etiology diagnosis Diagnosis, Differential

来  源:   DOI:10.1177/03000605241259764   PDF(Pubmed)

Abstract:
Nodular fasciitis (NF) is a benign and self-limiting fibroblastic proliferation that originates from the superficial fascia and extends into the subcutaneous tissue or muscle. It typically manifests in individuals aged 20 to 35 years, with rare occurrences observed in patients over the age of 60 years. We herein report a case involving a 75-year-old man with NF in the right vocal cord. The patient sought medical attention at the Department of Otolaryngology of our hospital because of a 1-month history of hoarseness and breathlessness. The diagnosis was unable to be confirmed through preoperative pathological examination. After admission to our hospital, various examinations were completed and surgical treatment was performed, and the postoperative histopathological findings revealed the presence of NF in the right vocal cord. NF of the vocal cord is a rare clinical entity. Given its rapid progression and propensity for marked infiltration, it often poses diagnostic challenges because it can mimic various malignant soft tissue tumors. Therefore, thorough exclusion of other neoplastic lesions is imperative prior to confirming the diagnosis of NF through pathological examination. Local surgical resection remains the primary treatment modality.
摘要:
结节性筋膜炎(NF)是一种良性和自限性成纤维细胞增殖,起源于浅筋膜并延伸到皮下组织或肌肉。它通常表现在20至35岁的个体中,在60岁以上的患者中观察到罕见的情况。我们在此报告一例涉及一名75岁男性右声带NF。由于有1个月的声音嘶哑和呼吸困难的病史,该患者在我们医院的耳鼻喉科寻求医疗护理。通过术前病理检查无法确诊。入院后,完成了各种检查并进行了手术治疗,术后组织病理学发现右声带中存在NF。声带的NF是一种罕见的临床实体。鉴于其快速发展和明显渗透的倾向,它通常会带来诊断挑战,因为它可以模拟各种恶性软组织肿瘤。因此,在通过病理检查确认NF的诊断之前,必须彻底排除其他肿瘤性病变。局部手术切除仍然是主要的治疗方式。
公众号