PDF(Pubmed)
Abstract：
BACKGROUND: Stroke is the second leading cause of death in Europe. In the case of stroke survival (almost 70%), only 25% of patients recover completely, while the remaining 75% will undergo a rehabilitation phase that varying from months to years. The primary outcomes of a stroke involve motor impairment in the upper limbs, resulting in a partial or complete inability to move the limb on the right or left side, depending on the affected hemisphere. Furthermore, the motor deficit distorts the proprioception of the body and the embodiment ability of the injured limb. This could be rehabilitated through the paradigm of body illusion that modulates the motor rehabilitation. The present protocol aims to investigate the effectiveness of a Virtual Reality system for sensorimotor and proprioception upper limb deficit compared to a traditional upper limb rehabilitation program.
METHODS: This study has a randomized and controlled design with control and experimental groups, and 4 measurement times: pre-intervention, immediately after the intervention, and two follow-ups (at 6 and 12 months). The inclusion criteria are: (a) Being 18 to 85 years old, both males and females; (b) Suffering from ischemic or haemorrhagic stroke; (c) The stroke event must have occurred from two to eighteen months before recruitment; (d) Patients must have moderate to severe upper limb motor deficit, and the alteration of sensorimotor and proprioception abilities of the injury upper limb; (e) Patients must understand and sign the written consent for enrolment. The rehabilitation last four weeks with three sessions per week at Bellaria Hospital of Bologna (Italy). The VR protocol uses two types of technology: immersive and non-immersive, and the control group follow the traditional rehabilitation program.
METHODS: This study has a randomized and controlled design with control and experimental groups, and 4 measurement times: pre-intervention, immediately after the intervention, and two follow-ups (at 6 and 12 months). The inclusion criteria are: (a) Being 18 to 85 years old, both males and females; (b) Suffering from ischemic or haemorrhagic stroke; (c) The stroke event must have occurred from two to eighteen months before recruitment; (d) Patients must have moderate to severe upper limb motor deficit, and the alteration of sensorimotor and proprioception abilities of the injury upper limb; (e) Patients must understand and sign the written consent for enrolment. The rehabilitation last four weeks with three sessions per week at Bellaria Hospital of Bologna (Italy). The VR protocol uses two types of technology: immersive and non-immersive, and the control group follow the traditional rehabilitation program.
摘要：
背景：中风是欧洲第二大死亡原因。在卒中生存率（近70％）的情况下，只有25%的病人完全康复,而剩下的75%将经历从几个月到几年不等的康复阶段。中风的主要结果包括上肢运动障碍，导致部分或完全无法在右侧或左侧移动肢体，取决于受影响的半球。此外，运动缺陷会扭曲身体的本体感觉和受伤肢体的体现能力。这可以通过调节运动康复的身体错觉范式来修复。与传统的上肢康复计划相比，本协议旨在研究虚拟现实系统对感觉运动和本体感觉缺陷的有效性。
方法：本研究采用随机对照设计，对照组和实验组，和4次测量：干预前，干预后立即，两次随访（6个月和12个月）。纳入标准是：（a）18至85岁，男性和女性；(b)患有缺血性或出血性中风；(c)中风事件必须在招募前2至18个月发生；(d)患者必须有中度至重度上肢运动功能障碍，以及损伤上肢的感觉运动和本体感觉能力的改变；（e）患者必须理解并签署书面同意登记。康复治疗持续四周，每周在博洛尼亚Bellaria医院（意大利）进行三次治疗。VR协议使用两种类型的技术：沉浸式和非沉浸式，对照组遵循传统的康复方案。
方法：本研究采用随机对照设计，对照组和实验组，和4次测量：干预前，干预后立即，两次随访（6个月和12个月）。纳入标准是：（a）18至85岁，男性和女性；(b)患有缺血性或出血性中风；(c)中风事件必须在招募前2至18个月发生；(d)患者必须有中度至重度上肢运动功能障碍，以及损伤上肢的感觉运动和本体感觉能力的改变；（e）患者必须理解并签署书面同意登记。康复治疗持续四周，每周在博洛尼亚Bellaria医院（意大利）进行三次治疗。VR协议使用两种类型的技术：沉浸式和非沉浸式，对照组遵循传统的康复方案。
