METHODS: This study has a randomized and controlled design with control and experimental groups, and 4 measurement times: pre-intervention, immediately after the intervention, and two follow-ups (at 6 and 12 months). The inclusion criteria are: (a) Being 18 to 85 years old, both males and females; (b) Suffering from ischemic or haemorrhagic stroke; (c) The stroke event must have occurred from two to eighteen months before recruitment; (d) Patients must have moderate to severe upper limb motor deficit, and the alteration of sensorimotor and proprioception abilities of the injury upper limb; (e) Patients must understand and sign the written consent for enrolment. The rehabilitation last four weeks with three sessions per week at Bellaria Hospital of Bologna (Italy). The VR protocol uses two types of technology: immersive and non-immersive, and the control group follow the traditional rehabilitation program.
方法:本研究采用随机对照设计,对照组和实验组,和4次测量:干预前,干预后立即,两次随访(6个月和12个月)。纳入标准是:(a)18至85岁,男性和女性;(b)患有缺血性或出血性中风;(c)中风事件必须在招募前2至18个月发生;(d)患者必须有中度至重度上肢运动功能障碍,以及损伤上肢的感觉运动和本体感觉能力的改变;(e)患者必须理解并签署书面同意登记。康复治疗持续四周,每周在博洛尼亚Bellaria医院(意大利)进行三次治疗。VR协议使用两种类型的技术:沉浸式和非沉浸式,对照组遵循传统的康复方案。