关键词: gastrointestinal function midazolam:pediatric surgery preoperative anxiety

Mesh : Humans Hernia, Inguinal / surgery Laparoscopy Male Female Child, Preschool Anxiety Child Ligation Midazolam / pharmacology administration & dosage Recovery of Function Gastrointestinal Tract / surgery

来  源:   DOI:10.2147/DDDT.S461097   PDF(Pubmed)

Abstract:
UNASSIGNED: Anxiety and depression can affect the physiology of the gastrointestinal tract through the brain-gut axis, causing gastrointestinal dysfunction, which is mainly manifested as indigestion, diarrhoea, constipation, or abdominal pain. Preoperative anxiety arises in children due to separation from parents, fear of unfamiliar surroundings and anaesthesia and surgical procedures.To discuss the effect of alleviating preoperative anxiety on postoperative recovery of gastrointestinal function in children with indirect inguinal hernia after laparoscopic high ligation of the hernia sac.
UNASSIGNED: 90 children with laparoscopic high ligation of the herniated sac in oblique inguinal hernia were randomly divided into control group (Group C) and experimental group (Group M). The Group M was given midazolam oral solution 0.5mg/kg (maximum dose 20mg), and The Group C was given 5% glucose solution with the same dose.Primary outcome was the time to first postoperative defecation and I-FEED scores.The secondary outcomes included mYPAS-SF scores; child sedation scores; child-parent separation scores; parental STAI scores;PHBQ scores;FLACC scores, operative time, and fluid input and surgeon job satisfaction.
UNASSIGNED: Compared with Group C, there was a shorter time to first postoperative defecation (P < 0.05), and lower I-FEED scores on postoperative day 1 (P < 0.05). The mYPAS-SF scores, which were significantly different in Group M at T1, T2, and T3 (P < 0.05), parental STAI scores at S1, child sedation scores and child-parent separation scores in T1, and surgeon job satisfaction between the two groups were significantly different (P < 0.05). There were no statistically significant differences in I-FEED scores on days 2 and 3, PHBQ scores, FLACC scores, operative time, and fluid input between the two groups of children (P > 0.05).
UNASSIGNED: Preoperative application of midazolam oral solution to relieve preoperative anxiety helps to promote the recovery of postoperative gastrointestinal function in children with indirect inguinal hernia and increases the surgeon job satisfaction.
摘要:
焦虑和抑郁可以通过脑-肠轴影响胃肠道的生理,导致胃肠功能紊乱,主要表现为消化不良,腹泻,便秘,或腹痛。由于与父母分离,儿童会出现术前焦虑,害怕陌生的环境和麻醉和外科手术。探讨缓解术前焦虑对小儿腹股沟斜疝腹腔镜疝囊高位结扎术后胃肠功能恢复的影响。
90例腹腔镜下腹股沟斜疝疝囊高位结扎术患儿随机分为对照组(C组)和实验组(M组)。M组给予咪达唑仑口服溶液0.5mg/kg(最大剂量20mg),C组给予相同剂量的5%葡萄糖溶液。主要结果是术后首次排便时间和I-FEED评分。次要结果包括mYPAS-SF评分;儿童镇静评分;儿童-父母分离评分;父母STAI评分;PHBQ评分;FLACC评分,手术时间,流体输入和外科医生工作满意度。
与C组相比,术后首次排便时间较短(P<0.05),术后第1天I-FEED评分较低(P<0.05)。mYPAS-SF分数,M组在T1、T2和T3时差异有统计学意义(P<0.05),S1时的父母STAI评分、T1时的儿童镇静评分和儿童-父母分离评分以及外科医生工作满意度两组间差异有统计学意义(P<0.05)。第2天和第3天的I-FEED评分、PHBQ评分、FLACC分数,手术时间,两组患儿的液体输入量比较(P>0.05)。
术前应用咪达唑仑口服液缓解术前焦虑,有助于促进腹股沟斜疝患儿术后胃肠功能恢复,提高外科医生工作满意度。
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