关键词: appetite-related peptides exercise ghrelin leptin obesity overweight physical activity training

Mesh : Ghrelin / blood Humans Leptin / blood Obesity / blood therapy Endurance Training / methods Overweight / blood therapy metabolism Resistance Training Exercise / physiology

来  源:   DOI:10.3390/ijms25158067   PDF(Pubmed)

Abstract:
Exercise training is a valuable tool for improving body weight and composition in overweight or obese adults, which leads to a negative energy balance. It is relevant to consider whether exercise can help people lose weight or prevent weight gain because any energy expended in exercise increases the severity of hunger and promotes food consumption. Over the past decade, the identification of the circulating peptide ghrelin, which alerts the brain to the body\'s nutritional state, has significantly expanded our understanding of this homeostatic mechanism that controls appetite and body weight. To shed more light on this issue, we decided to investigate the effects of resistance and endurance training on plasma ghrelin and leptin levels. In addition, we sought to understand the mechanisms by which acute and chronic exercise can regulate hunger. This review analyzes studies published in the last fifteen years that focused on changes suffered by ghrelin, leptin, or both after physical exercise in overweight or obese individuals. Most studies have shown a decrease in leptin levels and an increase in ghrelin levels in these cases. Exercise regimens that support weight maintenance need further investigation.
摘要:
运动训练是改善超重或肥胖成年人体重和成分的宝贵工具,导致负能量平衡。有必要考虑运动是否可以帮助人们减肥或防止体重增加,因为运动中消耗的任何能量都会增加饥饿的严重程度并促进食物消耗。在过去的十年里,循环肽ghrelin的鉴定,提醒大脑注意身体的营养状态,大大扩展了我们对这种控制食欲和体重的稳态机制的理解。为了进一步阐明这个问题,我们决定研究抵抗力和耐力训练对血浆ghrelin和leptin水平的影响。此外,我们试图了解急性和慢性运动调节饥饿的机制。这篇综述分析了过去十五年发表的研究,这些研究的重点是ghrelin所遭受的变化,瘦素,或者在超重或肥胖个体的体育锻炼后两者兼而有之。大多数研究表明,在这些情况下,瘦素水平降低,生长素释放肽水平升高。支持体重维持的运动方案需要进一步研究。
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