PDF(Pubmed)
Abstract：
Aralia continentalis Kitag. (A. continentalis) holds significant medicinal value among the Aralia genus. It has traditionally been employed in ethnomedicine to address a wide range of conditions, including wind-cold-dampness arthralgia; rheumatic pain in the waist and lower extremities; lumbar muscular strain; injuries resulting from falls, fractures, contusions, and strains; headache; toothache; and abscesses. Modern pharmacological research has validated its therapeutic potential, encompassing anti-inflammatory, analgesic, antioxidant, antimicrobial, insecticidal, hepatoprotective, anti-diabetic, and cytotoxic properties, among other pharmacological effects. To compile comprehensive knowledge on A. continentalis, a rigorous literature search was undertaken utilizing databases like SciFinder, PubMed, and Web of Science. This review seeks to delve into the plant\'s traditional applications, geographical distribution, botanical characteristics, phytochemistry, and pharmacology. The objective is to lay a foundation and propose novel research directions for exploring the plant\'s potential applications. Currently, one hundred and fifty-nine compounds have been isolated and identified from A. continentalis, encompassing diterpenoids, steroids, triterpenoids, volatile components, phenolics, vitamins, trace elements, and other compounds. Notably, diterpenoids, steroids, triterpenoids, volatile components, and phenolics have exhibited pronounced pharmacological effects, such as anti-inflammatory, analgesic, antioxidant, hepatoprotective, antidiabetic, and antimicrobial activities. However, despite the extensive research conducted, further studies are imperative to unravel new components and mechanisms of action, necessitating more in-depth investigations. This comprehensive exploration could pave the way for advancing and harnessing the potential of A. continentalis.
摘要：
AraliacontinentalisKitag.(A.大陆）在Aralia属中具有重要的药用价值。传统上，它被用于民族医学，以解决广泛的条件，包括风寒湿关节痛；腰部和下肢风湿性疼痛；腰部肌肉劳损；跌倒造成的伤害，骨折,挫伤,和紧张；头痛；牙痛；和脓肿。现代药理学研究已经验证了其治疗潜力，包括抗炎，镇痛药,抗氧化剂，抗菌，杀虫,保肝,抗糖尿病，和细胞毒性，在其他药理作用中。为了编写关于美洲大陆的全面知识，利用SciFinder等数据库进行了严格的文献检索，PubMed,和WebofScience。这篇综述旨在深入研究该工厂的传统应用，地理分布,植物学特征,植物化学,和药理学。目的是为探索植物的潜在应用奠定基础并提出新的研究方向。目前,已从A.continentalis中分离并鉴定了一百五十九种化合物，包括二萜，类固醇,三萜类，挥发性成分,酚类物质,维生素,微量元素,和其他化合物。值得注意的是,二萜,类固醇,三萜类，挥发性成分,和酚类物质表现出明显的药理作用，如抗炎，镇痛药,抗氧化剂，保肝,抗糖尿病药,和抗菌活性。然而,尽管进行了广泛的研究，进一步的研究必须解开新的组成部分和作用机制，需要进行更深入的调查。这种全面的探索可以为推进和利用美洲大陆的潜力铺平道路。
