关键词: 3D printing 3D slicer Clinical application Deep intracerebral micro cavernous hemangiomas Transcranial neuroendoscope

Mesh : Humans Female Printing, Three-Dimensional Male Adult Adolescent Child Middle Aged Neuroendoscopy / methods Retrospective Studies Young Adult Hemangioma, Cavernous, Central Nervous System / surgery diagnostic imaging Magnetic Resonance Imaging / methods Imaging, Three-Dimensional / methods Brain Neoplasms / surgery diagnostic imaging pathology Hemangioma, Cavernous / surgery diagnostic imaging pathology Tomography, X-Ray Computed

来  源:   DOI:10.1038/s41598-024-68068-5   PDF(Pubmed)

Abstract:
To explore the advantages and disadvantages of 3D Slicer reconstruction and 3D printing localization combined with transcranial neuroendoscope in the surgical treatment of deep cerebral micro cavernous hemangiomas. Method The clinical data of patients with deep cerebral micro cavernous hemangiomas treated by our hospital from June 2022 to February 2023 using 3D Slicer reconstruction and 3D printing localization technology combined with transcranial endoscopic surgery were retrospectively analyzed. A total of 5 cases with complete data were collected, including 2 males and 3 females, aged 9-59 years. All 5 patients had deep supratentorial cavernous hemangiomas with a diameter of less than 1.5 cm, and had clinical symptoms such as headache or epilepsy, and had been diagnosed by CT or MRI. Repeated bleeding from small cavernous hemangiomas in the deep brain can lead to clinical symptoms such as recurrent headache and epilepsy, and is required surgical treatment. However, cavernous hemangiomas often have smaller lesions and are difficult to locate in the deep part. Without neuronavigation, surgery can become extremely difficult. Our team\'s newly developed 3D Slicer reconstruction and 3D printing localization technology which could provide new options for surgical treatment of small cavernous hemangiomas or other small lesions in the deep brain, but its accuracy and safety still need to be verified by further clinical research.
摘要:
探讨3D切片器重建和3D打印定位联合经颅神经内镜在脑深部微小海绵状血管瘤手术治疗中的优缺点。方法回顾性分析我院2022年6月至2023年2月采用3D切片器重建和3D打印定位技术联合经颅内镜手术治疗的脑深部微海绵状血管瘤患者的临床资料。共收集5例资料完整,包括2名男性和3名女性,9-59岁。5例患者均为深幕上海绵状血管瘤,直径小于1.5cm,有头痛或癫痫等临床症状,并通过CT或MRI诊断。脑深部小海绵状血管瘤反复出血可导致临床症状,如反复发作的头痛和癫痫,需要手术治疗。然而,海绵状血管瘤通常有较小的病变,很难在深部定位。没有神经导航,手术可能变得极其困难。我们的团队新开发的3D切片器重建和3D打印定位技术,可以为小型海绵状血管瘤或其他脑深部小病变的手术治疗提供新的选择。但其准确性和安全性仍需进一步的临床研究验证。
公众号