Abstract：
A 77-year-old man presented with right inguinal lymphadenopathy and swollen parotid and submandibular glands bilaterally. Histopathology revealed germinal center B-cell type diffuse large B-cell lymphoma (DLBCL) in the inguinal lymph node. Lymphocyte and plasma cell infiltration in the submandibular gland with elevated serum IgG4 levels (13 g/L) prompted a diagnosis of IgG4-related disease (IgG4-RD). Systemic chemotherapy for DLBCL led to shrinkage of the lymph nodes and disappearance of the submandibular gland swelling, as confirmed by fluorodeoxyglucose-positron emission tomography/computed tomography. Although concomitant IgG4-RD and lymphoma have been reported, their simultaneous diagnosis is rare; therefore, a biopsy of all involved organs is crucial in cases with unusual organ involvement.
摘要：
一名77岁的男子表现为右侧腹股沟淋巴结肿大，双侧腮腺和颌下腺肿胀。组织病理学显示腹股沟淋巴结中的生发中心B细胞型弥漫性大B细胞淋巴瘤（DLBCL）。血清IgG4水平升高（13g/L）的下颌下腺中的淋巴细胞和浆细胞浸润促使诊断为IgG4相关疾病（IgG4-RD）。DLBCL的全身化疗导致淋巴结缩小和下颌下腺肿胀消失，氟脱氧葡萄糖-正电子发射断层扫描/计算机断层扫描证实。尽管已经报道了合并的IgG4-RD和淋巴瘤，他们同时诊断是罕见的；因此，在异常器官受累的情况下，对所有受累器官进行活检至关重要。
