关键词: Antioxidants Coenzyme Q10 Polyphenols Resveratrol Selenium UV radiation Vitamin A Vitamin C Vitamin E age-related skin alterations. anti-inflammatory anticarcinogenic cell repair collagen synthesis dietary intake energy production green tea extract holistic approach oxidative stress photoprotection pollution regeneration retinol skin health skincare products

来  源:   DOI:10.2174/012772574X311177240710100118

Abstract:
Antioxidants play a pivotal role in maintaining skin health and integrity, combating the deleterious effects of oxidative stress induced by environmental aggressors such as UV ra-diation, pollution, and lifestyle factors. This paper reviews the contributions of key antioxidants, including Vitamin C, Vitamin E, Vitamin A, green tea extract, Coenzyme Q10, Resveratrol, Selenium, and Polyphenols, in skin health care. Vitamin C, known for its collagen synthesis promotion and photoprotection properties, alongside Vitamin E, a lipid-soluble antioxidant, syn-ergistically works to neutralize free radicals and repair damaged skin cells. Vitamin A, in the form of retinol, plays a critical role in skin cell regeneration and the maintenance of skin integ-rity. Green tea extract, rich in Polyphenols, offers anti-inflammatory and anticarcinogenic prop-erties, making it a potent ingredient for skin protection. Coenzyme Q10, a naturally occurring antioxidant in the body, aids in energy production for cell repair and regeneration, while Resveratrol, found in grapes and berries, provides anti-ageing benefits by enhancing skin\'s re-sistance to oxidative stress. Selenium, an essential mineral, contributes to the protection of skin cells from oxidative damage. The incorporation of these antioxidants in skincare products and dietary sources is discussed, highlighting the importance of a holistic approach in skincare re-gimes. The paper emphasizes the synergy between topical applications and dietary intake of antioxidants, advocating for a comprehensive strategy for promoting skin health and preventing age-related skin alterations. Method: For the review article, a variety of search engines and databases were used to identify relevant articles. Furthermore, for biomedical literature focusing on antioxidants and their ef-fects on skin health, PubMed was used. Moreover, to access a wide range of scholarly articles, including those related to dermatology and skincare, Google Scholar was used. Scopus provides comprehensive coverage of peer-reviewed literature across various scientific disciplines. Web of Science identifies high-impact articles and research on antioxidants in skincare. In addition, for accessing full-text articles on antioxidants and their applications in dermatology, Science Direct was used. The inclusion criteria for the review paper were as follows: only studies pub-lished in peer-reviewed journals were included to ensure the credibility and reliability of the information. Articles published in English were considered, to avoid language-related biases and ensure comprehension. Studies published within the last 10 years were included to provide the most current insights into antioxidant research in skincare. Articles must specifically focus on the role of antioxidants (Vitamin C, Vitamin E, Vitamin A, green tea extract, Coenzyme Q10, Resveratrol, Selenium, Polyphenols) in skin health care. Both experimental studies (in vivo and in vitro) and clinical trials were included to provide a comprehensive overview of the antioxidant effects. Full-text articles were included to allow for thorough data extraction and analysis. The exclusion criteria for the review paper were as follows: Publications that were not peer-re-viewed, such as editorials, opinion pieces, and non-scholarly articles, were excluded. Articles published in languages other than English were excluded due to potential translation challenges and to maintain consistency. Studies that did not focus on the specified antioxidants or their impact on skin health were excluded. Duplicate publications were excluded to avoid redundancy in the review. Articles with insufficient or incomplete data were excluded to ensure the quality and reliability of the review findings.
摘要:
抗氧化剂在保持皮肤健康和完整性方面发挥着关键作用,对抗由环境侵略者诱导的氧化应激的有害影响,如紫外线辐射,污染,和生活方式因素。本文综述了关键抗氧化剂的贡献,包括维生素C,维生素E,维生素A,绿茶提取物,辅酶Q10,白藜芦醇,硒,和多酚,在皮肤保健。维生素C,以其胶原蛋白合成促进和光保护特性而闻名,除了维生素E,一种脂溶性抗氧化剂,syn-人体工程学中和自由基和修复受损的皮肤细胞。维生素A,以视黄醇的形式,在皮肤细胞再生和维持皮肤完整性中起着至关重要的作用。绿茶提取物,富含多酚,提供抗炎和抗癌功能,使其成为保护皮肤的有效成分。辅酶Q10,一种体内天然存在的抗氧化剂,有助于细胞修复和再生的能量产生,而白藜芦醇,在葡萄和浆果中发现,通过增强皮肤对氧化应激的抵抗力来提供抗衰老的益处。硒,一种必需的矿物质,有助于保护皮肤细胞免受氧化损伤。讨论了这些抗氧化剂在护肤产品和饮食来源中的掺入,强调整体方法在护肤品中的重要性。本文强调了局部应用和饮食摄入抗氧化剂之间的协同作用,倡导促进皮肤健康和预防与年龄有关的皮肤变化的综合策略。方法:对于评论文章,各种搜索引擎和数据库被用来识别相关文章。此外,关注抗氧化剂及其对皮肤健康的影响的生物医学文献,使用了PubMed。此外,访问广泛的学术文章,包括与皮肤病学和护肤有关的,使用GoogleScholar。Scopus全面覆盖了各个科学学科的同行评审文献。WebofScience确定了有关护肤中抗氧化剂的高影响力文章和研究。此外,访问有关抗氧化剂及其在皮肤病学中的应用的全文文章,使用了ScienceDirect。综述论文的纳入标准如下:仅纳入在同行评审期刊上发表的研究,以确保信息的可信度和可靠性。用英语发表的文章被认为,避免与语言相关的偏见并确保理解。包括过去10年发表的研究,以提供有关护肤品中抗氧化剂研究的最新见解。文章必须特别关注抗氧化剂(维生素C,维生素E,维生素A,绿茶提取物,辅酶Q10,白藜芦醇,硒,多酚)在皮肤保健中。包括实验研究(体内和体外)和临床试验,以全面概述抗氧化作用。包括全文文章,以便进行彻底的数据提取和分析。审查文件的排除标准如下:未经同行审查的出版物,比如社论,意见片,和非学术性文章,被排除在外。以英语以外的语言发表的文章由于潜在的翻译挑战和保持一致性而被排除在外。不关注指定抗氧化剂或其对皮肤健康影响的研究被排除在外。重复的出版物被排除在外,以避免审查中的冗余。数据不足或不完整的文章被排除在外,以确保审查结果的质量和可靠性。
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