目的:本研究旨在探讨早期胃癌(GC)根治术后男性和女性术后饮食摄入(DI)减少的差异,并确定对两性有效的营养支持。
方法:这种前瞻性,观察性研究纳入了因GC接受胃切除术的患者。在手术前和术后1个月和3个月的营养咨询期间,使用包含82种食物的食物频率问卷(FFQW82)评估DI。
结果:所有参与者的术前DI中位数为1,856.3千卡/天,1个月和3个月时的DI分别为1,532.5千卡/天和1,637千卡/天,分别。男性和女性的术前DI中位数为1805千卡/天(1,300-2,330千卡/天)和1481千卡/天(1,126-1,957千卡/天),分别(p<0.0001)。男性和女性在1个月时的平均DI为1627(1,101-2,195)千卡/天和1,308(986-1,915)千卡/天,分别(p<0.0001)。术后3个月,男性的平均DI为1737(1,130-2,443)千卡/天,女性为1428(816-2,005)千卡/天(p<0.0001)。然而,1个月时的DI损失率没有显着差异(中位数:-9.7%与-9.3%,p=0.765)和3个月(中位数:-3.5%vs.-4.8%,p=0.137)男女之间。
结论:尽管男性和女性在胃切除术后的DI损失率几乎相似,术后DI和DI损失差异显著。因此,在评估胃切除术后额外营养支持如口服营养补充剂的疗效时,应考虑男性和女性胃切除术后DI丢失的差异.
OBJECTIVE: This study aimed to investigate the differences in the postoperative dietary intake (DI) loss between men and women after radical resection for early gastric cancer (GC), and to identify effective nutritional support for both sexes.
METHODS: This prospective, observational study enrolled patients who underwent gastrectomy for GC. DI was assessed using the food frequency questionnaire containing 82 food items (FFQW82) during nutritional counseling before surgery and one and three months postoperatively.
RESULTS: The median preoperative DI of all participants was 1,856.3 kcal/day, and DI at 1 and 3 months were 1,532.5 kcal/day and 1,637 kcal/day, respectively. The median preoperative DI was 1805 kcal/day (1,300-2,330 kcal/day) and 1481 kcal/day (1,126-1,957 kcal/day) in men and women, respectively (p<0.0001). The median DI at 1 month was 1627 (1,101-2,195) kcal/day and 1,308 (986-1,915) kcal/day in men and women, respectively (p<0.0001). At 3 months postoperatively, the median DI was 1737 (1,130-2,443) kcal/day in men and 1428 (816-2,005) kcal/day in women (p<0.0001). However, there was no significant difference in the DI loss rate at 1 month (median: -9.7% vs. -9.3%, p=0.765) and 3 months (median: -3.5% vs. -4.8%, p=0.137) between men and women.
CONCLUSIONS: Although the DI loss rate in men and women after gastrectomy for GC was almost similar, the postoperative DI and DI loss differed significantly. Therefore, differences in DI loss after gastrectomy between men and women should be considered while assessing the efficacy of additional nutritional support such as oral nutritional supplements after gastrectomy.