PDF(Pubmed)
Abstract：
Human Papillomavirus (HPV) vaccine coverage was <50% in France in 2022 and even lower among socially disadvantaged populations. We aimed to evaluate socio-demographic determinants of HPV vaccine awareness, uptake, and intention among parents of adolescents, and related attitudes and knowledge items. Parents of adolescents attending middle schools across France, who participated in a randomized trial responded to an anonymous baseline survey, conducted between November 2021 and February 2022. We used logistic regression models adjusting for a child\'s age and sex to explore sociodemographic determinants (including at-home multilingualism, occupational categories, local deprivation index and urbanity) of HPV vaccine awareness, uptake, and intention. Among the 1889 participants from 61 schools, parents working as factory workers/farmers had significantly lower odds of vaccine awareness compared to executives/professionals, both if they reported (OR = 0.07; 0.03-0.15) or not (OR = 0.20; 0.11-0.36) speaking also another language than French at home. Parents in lower occupational categories with multilingual families were less likely to have the intention to vaccinate their child (OR = 0.19; 0.07-0.56). Recent physician visit or vaccine offer was strong positive determinants of awareness, uptake and intention. A substantial gradient across occupational categories was observed for attitudes and knowledge around HPV vaccine usefulness, safety, and accessibility. This study confirms the disparities on HPV vaccine uptake in France and provides insight into mechanisms of social disparities in HPV vaccine awareness, access and intention.
摘要：
2022年，法国的人乳头瘤病毒（HPV）疫苗覆盖率<50％，在社会弱势群体中甚至更低。我们旨在评估HPV疫苗意识的社会人口统计学决定因素，摄取，以及青少年父母的意愿，以及相关的态度和知识项目。在法国各地上中学的青少年家长，参加随机试验的人对匿名基线调查做出了回应，在2021年11月至2022年2月期间进行。我们使用逻辑回归模型来调整儿童的年龄和性别，以探索社会人口统计学决定因素（包括在家使用多种语言，职业类别,当地剥夺指数和城市化）对HPV疫苗的认识，摄取，和意图。在来自61所学校的1889名参与者中，与高管/专业人员相比，作为工厂工人/农民工作的父母对疫苗的认识几率大大降低，如果他们报告（OR=0.07;0.03-0.15）或不报告（OR=0.20;0.11-0.36）在家里也说法语以外的另一种语言。具有多语言家庭的较低职业类别的父母不太可能打算给孩子接种疫苗（OR=0.19；0.07-0.56）。最近的医生访问或疫苗提供是意识的强烈积极决定因素，吸收和意图。关于HPV疫苗有用性的态度和知识在职业类别中观察到了很大的梯度，安全,和可访问性。这项研究证实了法国HPV疫苗摄取的差异，并提供了对HPV疫苗意识的社会差异机制的见解。访问和意图。
