PDF(Pubmed)
Abstract：
BACKGROUND: Our aim was to determine whether the Apparent Diffusion Coefficient is able to predict the presence of a symptomatic pineal cyst by detecting cerebral edema.
METHODS: We retrospectively analyzed MRIs of 45 patients with pineal cysts before and after resection and 51 patients without pineal cysts, comparing ADC values of thalamus, central, periventricular and subcortical white matter. Furthermore we evaluated cyst size and morphology and analyzed its correlation to ADC values in corresponding patients.
RESULTS: Differences between patients with symptomatic pineal cyst and control group were not significant (p = 0.200 - 0.968). ADC ratios did not change significantly after resection of the cyst (p = 0.575 - 0.862). Cyst size showed no significant correlation to ADC ratios (p = 0.071 - 0.918). Raw data analyses revealed more significance, especially periventricularly and in central white matter, which resulted in significant interhemispheric differences in ADC ratios in both subgroups (p < 0.001 and p = 0.031). MRI of 1.5T showed consistently higher values than 3T but mostly insignificant.
CONCLUSIONS: Our analysis revealed no evidence that pineal cysts lead to intracerebral edema caused by venous compression. Since variability was higher than the differences seen, ADC sequences do not appear to be an appropriate diagnostic tool for symptomatic pineal cysts.
METHODS: We retrospectively analyzed MRIs of 45 patients with pineal cysts before and after resection and 51 patients without pineal cysts, comparing ADC values of thalamus, central, periventricular and subcortical white matter. Furthermore we evaluated cyst size and morphology and analyzed its correlation to ADC values in corresponding patients.
RESULTS: Differences between patients with symptomatic pineal cyst and control group were not significant (p = 0.200 - 0.968). ADC ratios did not change significantly after resection of the cyst (p = 0.575 - 0.862). Cyst size showed no significant correlation to ADC ratios (p = 0.071 - 0.918). Raw data analyses revealed more significance, especially periventricularly and in central white matter, which resulted in significant interhemispheric differences in ADC ratios in both subgroups (p < 0.001 and p = 0.031). MRI of 1.5T showed consistently higher values than 3T but mostly insignificant.
CONCLUSIONS: Our analysis revealed no evidence that pineal cysts lead to intracerebral edema caused by venous compression. Since variability was higher than the differences seen, ADC sequences do not appear to be an appropriate diagnostic tool for symptomatic pineal cysts.
摘要：
背景：我们的目的是通过检测脑水肿来确定表观扩散系数是否能够预测有症状的松果体囊肿的存在。
方法：我们回顾性分析45例松果体囊肿切除前后和51例无松果体囊肿患者的MRI，比较丘脑的ADC值，中央,脑室周围和皮质下白质。此外，我们评估了相应患者的囊肿大小和形态，并分析了其与ADC值的相关性。
结果：有症状的松果体囊肿患者与对照组之间的差异不显著（p=0.200-0.968）。切除囊肿后，ADC比率没有显着变化（p=0.575-0.862）。囊肿大小与ADC比率没有显着相关性（p=0.071-0.918）。原始数据分析显示出更多的意义，尤其是脑室周围和中央白质，这导致两个亚组的ADC比率存在显著的半球间差异(p<0.001和p=0.031)。1.5T的MRI显示始终高于3T的值，但大多不明显。
结论：我们的分析显示没有证据表明松果体囊肿导致静脉压迫引起的脑水肿。由于变异性高于所看到的差异，ADC序列似乎不是有症状的松果体囊肿的适当诊断工具。
方法：我们回顾性分析45例松果体囊肿切除前后和51例无松果体囊肿患者的MRI，比较丘脑的ADC值，中央,脑室周围和皮质下白质。此外，我们评估了相应患者的囊肿大小和形态，并分析了其与ADC值的相关性。
结果：有症状的松果体囊肿患者与对照组之间的差异不显著（p=0.200-0.968）。切除囊肿后，ADC比率没有显着变化（p=0.575-0.862）。囊肿大小与ADC比率没有显着相关性（p=0.071-0.918）。原始数据分析显示出更多的意义，尤其是脑室周围和中央白质，这导致两个亚组的ADC比率存在显著的半球间差异(p<0.001和p=0.031)。1.5T的MRI显示始终高于3T的值，但大多不明显。
结论：我们的分析显示没有证据表明松果体囊肿导致静脉压迫引起的脑水肿。由于变异性高于所看到的差异，ADC序列似乎不是有症状的松果体囊肿的适当诊断工具。
