Abstract：
In an experimental model of Alzheimer\'s disease in mice, oral administration of trehalose disaccharide reduces neuroinflammation assessed by the expression level of microglia activation marker Iba1 and affects the neutrophil degranulation activity. A potential anti-inflammatory effect of 4% trehalose solution associated with a decrease in the activity of leukocyte elastase in plasma was revealed.
摘要：
在小鼠阿尔茨海默病的实验模型中,口服海藻糖二糖可减少通过小胶质细胞活化标志物Iba1表达水平评估的神经炎症，并影响中性粒细胞脱颗粒活性。揭示了与血浆中白细胞弹性蛋白酶活性降低相关的4％海藻糖溶液的潜在抗炎作用。
