PDF(Pubmed)
Abstract：
Incubation of craving is a phenomenon describing the intensification of craving for a reward over extended periods of abstinence from reinforcement. Animal models use instrumental markers of craving to reward cues to examine incubation, while human paradigms rely on subjective self-reports. Here, we characterize an animal-inspired, novel human paradigm that showed strong positive relationships between self-reports and instrumental markers of craving for favored palatable foods. Further, we found consistent nonlinear relationships with time since last consumption and self-reports, and preliminary patterns between time and instrumental responses. These findings provide a novel approach to establishing an animal-inspired human model of incubation.
摘要：
渴望的孵化是一种现象，描述了在长期的禁欲强化中对奖励的渴望加剧。动物模型使用渴望的工具标记来奖励线索来检查孵化，而人类范式依赖于主观的自我报告。这里,我们描述了一个受动物启发的人，新的人类范式显示了自我报告和渴望偏爱可口食物的工具标记之间的强烈正相关关系。Further,我们发现了自上次消费和自我报告以来与时间的一致非线性关系，以及时间和仪器反应之间的初步模式。这些发现为建立受动物启发的人类孵化模型提供了一种新颖的方法。
