Abstract：
Polyphenols, including phenolics, alkaloids, and terpenes, are secondary metabolites that are commonly found in fruits, vegetables, and beverages, such as tea, coffee, wine, chocolate, and beer. These compounds have gained considerable attention and market demand because of their potential health benefits. However, their application is limited due to their low absorption rates and reduced tissue distribution efficiency. Engineering polyphenol-protein complexes or conjugates can enhance the antioxidant properties, bioavailability, and stability of polyphenols and improve digestive enzyme hydrolysis, target-specific delivery, and overall biological functions. Complex polyphenols, such as melanin, tannins, and ellagitannins, can promote gut microbiota balance, bolster antioxidant defense, and improve overall human health. Despite these benefits, the safety of polyphenol complexes must be thoroughly evaluated before their use as functional food additives or supplements. This review provides a detailed overview of the types of macromolecular polyphenols, their chemical composition, and their role in food enrichment. The mechanisms by which complex polyphenols act as antioxidative, anti-inflammatory, and anticancer agents have also been discussed.
摘要：
多酚,包括酚类物质,生物碱，和萜烯,是水果中常见的次生代谢产物，蔬菜,和饮料，比如茶，咖啡,葡萄酒,巧克力,和啤酒。这些化合物由于其潜在的健康益处而获得了相当大的关注和市场需求。然而,由于它们的低吸收率和降低的组织分布效率,它们的应用受到限制。工程多酚-蛋白质复合物或缀合物可以增强抗氧化性能，生物利用度，和稳定的多酚和提高消化酶的水解，特定于目标的交付，和整体生物学功能。复杂的多酚，比如黑色素，单宁,和ellagitannins,可以促进肠道菌群平衡，增强抗氧化防御，改善整体人类健康。尽管有这些好处,在用作功能性食品添加剂或补充剂之前，必须彻底评估多酚复合物的安全性。这篇综述详细概述了大分子多酚的类型，它们的化学成分,以及它们在食物丰富中的作用。复杂多酚作为抗氧化作用的机制，抗炎,和抗癌剂也被讨论过。
