PDF(Pubmed)
Abstract：
OBJECTIVE: Mild cognitive impairment (MCI) is a unique indicator of underlying distress that may be strongly associated with suicide risk. Despite this, to date, no study has examined the association between MCI and suicidal ideation. Therefore, the present study aimed to examine the association between MCI and suicidal ideation among adults aged ≥65 years from 6 low- and middle-income countries (LMICs; China, Ghana, India, Mexico, Russia, and South Africa).
METHODS: Cross-sectional, nationally representative data from the World Health Organization\'s Study on Global Ageing and Adult Health were analyzed. MCI was defined using the National Institute on Aging-Alzheimer\'s Association criteria. Self-reported information on past 12-month suicidal ideation was collected. Multivariable logistic regression and meta-analysis were conducted to assess associations.
RESULTS: Data on 13,623 individuals aged ≥65 years were analyzed. The prevalence of suicidal ideation ranged from 0.5% in China to 6.0% in India, whereas the range of the prevalence of MCI was 9.7% (Ghana) to 26.4% (China). After adjustment for potential confounders, MCI was significantly associated with 1.66 (95% confidence interval [95% CI] = 1.12-2.46) times higher odds for suicidal ideation.
CONCLUSIONS: Mild cognitive impairment was significantly associated with higher odds for suicidal ideation among older adults in LMICs. Future longitudinal studies from LMICs are necessary to assess whether MCI is a risk factor for suicidal ideation.
METHODS: Cross-sectional, nationally representative data from the World Health Organization\'s Study on Global Ageing and Adult Health were analyzed. MCI was defined using the National Institute on Aging-Alzheimer\'s Association criteria. Self-reported information on past 12-month suicidal ideation was collected. Multivariable logistic regression and meta-analysis were conducted to assess associations.
RESULTS: Data on 13,623 individuals aged ≥65 years were analyzed. The prevalence of suicidal ideation ranged from 0.5% in China to 6.0% in India, whereas the range of the prevalence of MCI was 9.7% (Ghana) to 26.4% (China). After adjustment for potential confounders, MCI was significantly associated with 1.66 (95% confidence interval [95% CI] = 1.12-2.46) times higher odds for suicidal ideation.
CONCLUSIONS: Mild cognitive impairment was significantly associated with higher odds for suicidal ideation among older adults in LMICs. Future longitudinal studies from LMICs are necessary to assess whether MCI is a risk factor for suicidal ideation.
摘要：
目的：轻度认知障碍（MCI）是潜在痛苦的独特指标，可能与自杀风险密切相关。尽管如此,到目前为止,尚无研究检查MCI与自杀意念之间的关联.因此,本研究旨在研究来自六个低收入和中等收入国家(LMICs)的65岁以上成年人的MCI与自杀意念之间的关系(中国，加纳,印度,墨西哥,俄罗斯,南非)。
方法：横截面，我们分析了世界卫生组织关于全球老龄化和成人健康研究的全国代表性数据.MCI使用美国国家衰老-阿尔茨海默病协会标准进行定义。收集了过去12个月自杀意念的自我报告信息。进行多变量逻辑回归和荟萃分析以评估相关性。
结果：分析了13,623名年龄≥65岁个体的数据。自杀意念的患病率从中国的0.5%到印度的6.0%不等,MCI的患病率范围为9.7％（加纳）至26.4％（中国）。在调整了潜在的混杂因素后，MCI与1.66(95CI=1.12-2.46)倍的自杀意念几率显著相关。
结论：MCI与LMICs中老年人自杀意念的几率显著相关。LMIC未来的纵向研究对于评估MCI是否是自杀意念的危险因素是必要的。
方法：横截面，我们分析了世界卫生组织关于全球老龄化和成人健康研究的全国代表性数据.MCI使用美国国家衰老-阿尔茨海默病协会标准进行定义。收集了过去12个月自杀意念的自我报告信息。进行多变量逻辑回归和荟萃分析以评估相关性。
结果：分析了13,623名年龄≥65岁个体的数据。自杀意念的患病率从中国的0.5%到印度的6.0%不等,MCI的患病率范围为9.7％（加纳）至26.4％（中国）。在调整了潜在的混杂因素后，MCI与1.66(95CI=1.12-2.46)倍的自杀意念几率显著相关。
结论：MCI与LMICs中老年人自杀意念的几率显著相关。LMIC未来的纵向研究对于评估MCI是否是自杀意念的危险因素是必要的。
