Abstract：
BACKGROUND: Pelvic exenteration (PE) is an extensive surgical treatment reserved for advanced or recurrent pelvic neoplasms, with potential impacts on patients\' quality of life (QoL) poorly referenced in the literature.
OBJECTIVE: This study aimed to evaluate QoL outcomes among three types of PE.
METHODS: A cross-sectional study assessed 106 patients divided into anterior PE (APE), posterior PE (PPE), or total PE (TPE) groups. QoL was measured using e short form 36 version 2 (SF-36) and the European Organization for Research and Treatment of Cancer QoL Quality of Life Questionnaire Core 30 (QLQ-C30) QoL questionnaires. Descriptive and inferential analyses compared questionnaire scores.
RESULTS: The findings unveiled a balance among the three groups concerning demographic variables and comorbidities, with the exception of a male predominance in the APE and TPE cohorts. Notably, the APE group exhibited elevated scores in overall health (assessed via SF-36) and social functioning and diarrhea domains (assessed via QLQ-C30). Moreover, in terms of the fatigue and nausea/vomiting domains (assessed via QLQ-C30), the APE group demonstrated superior QoL compared to the PPE group. Conversely, the PPE group manifested a notably lower QoL in the constipation domain (assessed via QLQ-C30) compared to the other two groups. Additionally, disease recurrence was significantly associated with diminished QoL across multiple domains.
CONCLUSIONS: APE patients exhibited better QoL than PPE and TPE groups, with disease recurrence adversely affecting QoL.
OBJECTIVE: This study aimed to evaluate QoL outcomes among three types of PE.
METHODS: A cross-sectional study assessed 106 patients divided into anterior PE (APE), posterior PE (PPE), or total PE (TPE) groups. QoL was measured using e short form 36 version 2 (SF-36) and the European Organization for Research and Treatment of Cancer QoL Quality of Life Questionnaire Core 30 (QLQ-C30) QoL questionnaires. Descriptive and inferential analyses compared questionnaire scores.
RESULTS: The findings unveiled a balance among the three groups concerning demographic variables and comorbidities, with the exception of a male predominance in the APE and TPE cohorts. Notably, the APE group exhibited elevated scores in overall health (assessed via SF-36) and social functioning and diarrhea domains (assessed via QLQ-C30). Moreover, in terms of the fatigue and nausea/vomiting domains (assessed via QLQ-C30), the APE group demonstrated superior QoL compared to the PPE group. Conversely, the PPE group manifested a notably lower QoL in the constipation domain (assessed via QLQ-C30) compared to the other two groups. Additionally, disease recurrence was significantly associated with diminished QoL across multiple domains.
CONCLUSIONS: APE patients exhibited better QoL than PPE and TPE groups, with disease recurrence adversely affecting QoL.
摘要：
背景：盆腔切除术（PE）是一种针对晚期或复发性盆腔肿瘤的广泛手术治疗，对患者生活质量（QoL）的潜在影响在文献中引用很少。
目的：本研究旨在评估三种类型PE的QoL结果。
方法：一项横断面研究评估了106例分为前PE（APE）的患者，后PE（PPE），或总PE(TPE)组。QoL使用简表36版本2（SF-36）和欧洲癌症研究与治疗组织QoL生活质量问卷核心30（QLQ-C30）QoL问卷进行测量。描述性和推断性分析比较了问卷得分。
结果：研究结果揭示了三组人口统计学变量和合并症之间的平衡，除了在APE和TPE队列中以男性为主。值得注意的是,APE组的总体健康(通过SF-36评估),社会功能和腹泻领域(通过QLQ-C30评估)评分均升高.此外，在疲劳和恶心/呕吐方面（通过QLQ-C30评估），APE组的QoL优于PPE组.相反，与其他两组相比,PPE组在便秘领域的QoL显著降低(通过QLQ-C30评估).此外,疾病复发与多个领域的QoL降低显著相关.
结论：APE患者的QoL优于PPE和TPE组，疾病复发对QoL产生不利影响。
目的：本研究旨在评估三种类型PE的QoL结果。
方法：一项横断面研究评估了106例分为前PE（APE）的患者，后PE（PPE），或总PE(TPE)组。QoL使用简表36版本2（SF-36）和欧洲癌症研究与治疗组织QoL生活质量问卷核心30（QLQ-C30）QoL问卷进行测量。描述性和推断性分析比较了问卷得分。
结果：研究结果揭示了三组人口统计学变量和合并症之间的平衡，除了在APE和TPE队列中以男性为主。值得注意的是,APE组的总体健康(通过SF-36评估),社会功能和腹泻领域(通过QLQ-C30评估)评分均升高.此外，在疲劳和恶心/呕吐方面（通过QLQ-C30评估），APE组的QoL优于PPE组.相反，与其他两组相比,PPE组在便秘领域的QoL显著降低(通过QLQ-C30评估).此外,疾病复发与多个领域的QoL降低显著相关.
结论：APE患者的QoL优于PPE和TPE组，疾病复发对QoL产生不利影响。
